Objective To explore the operation effect of isometric reconstruction of the medial patellofemoral ligament with the semitendinosus tendon and direct suture rehabilitation of the medial patellofemoral ligament in the treatment of patellar dislocation,and provide some reference for the surgical treatment of this disease.Methods Forty patients with patellar dislocation included 20 patients with suture repair (suture group) and 20 patients with reconstruction (reconstruction group).The erythrocyte sedimentation rate,C-reactive protein were determined at 3,14 d after operation in two groups.The congruence angles (CA),lateal patellofemoral angle (LPA),lateral patellar displacement(LS) before and after operation,knee joint function,efficacy after operation were observed and compared.Results There was no significant difference in CA,LPA,LS between two groups (P ＞ 0.05).CA,LPA,LS after operation were improved compared with before operation in two groups [suture group:(9.13 ± 1.88)° vs.(16.50 ±2.83)°,(8.48 ± 1.19)° vs.(-1.28 ± 2.12)°,(0.52 ± 0.43)° vs.(0.78 ± 0.32)° ;reconstruction group:(6.69 ± 1.83)° vs.(16.95 ±3.17)°,(6.24 ± 1.33)° vs.(-0.91 ±2.00)°,(0.32 ±0.23)° vs.(0.70 ±0.16)°],and there was significant difference (P＜ 0.01).The improvement of CA,LPA,LS in reconstruction group were better than that in suture group,and there was significant difference (P＜ 0.01).The knee joint function score by Lysholm was (38.27 ± 17.06) scores in suture group,(79.44 ±9.86) scores in reconstruction group,and there was significant difference (P ＜ 0.05).There was no significant difference in the erythrocyte sedimentation rate,C-reactive protein at 3,14 d after operation between two groups (P ＞0.05).Conclusions The operation effect of isometric reconstruction of the medial patellofemoral ligament with the semitendinosus tendon method is better than the direct suture rehabilitation of the medial patellofemoral ligament method,the former can effectively restore the relationship between patella and femoral trochlea,and cure the dislocation of patella from the root.

OBJECTIVETo develop a new method to rapidly determine and identify Guizhi Fuling capsule by portable acousto-optic tunable filter-near infrared spectroscopy.

METHODThe qualitative model was set up using principal component analysis. The correlation models between the NIR spectra and the reference values of five major constituents were obtained with partial least squares method.

RESULTThe identifying model accurately identified Guizhi Fuling capsule, and quantitative analytical models could precisely predicted the content of ellagic acid, baicalin, benzoylpaenoniflorin, cinnamaldehyde, and paeonol. The correlation coefficients of the calibration models were 0.924 2, 0.938 4, 0.924 2, 0.933 6, 0.934 7, the validation set coefficients of the calibration were 0.924 2, 0.938 4, 0.924 2, 0.933 6, 0.934 7, and the RMSEP were 1.138%, 3.014%, 0.751%, 0.625%, 3.455%, 1.363%, respectively. The results of external validation showed no significant difference between the predictive and the determining values by t-test.

CONCLUSIONThe method is accurate, rapid and non-destructive, and can be used for determining and identifying Guizhi Fuling capsule.

Acetophenones ; analysis ; Acrolein ; analogs & derivatives ; analysis ; Calibration ; Capsules ; chemistry ; Drug Evaluation ; methods ; Drugs, Chinese Herbal ; analysis ; Ellagic Acid ; analysis ; Flavonoids ; analysis ; Least-Squares Analysis ; Models, Chemical ; Principal Component Analysis ; methods ; Spectroscopy, Near-Infrared ; methods