1.Clinical Significance of Serum IL-18 and IL-18BP in Patients with Primary Liver Cancer
Xianghui LIAO ; Chengnong GUAN ; Liangzhen CAI
Journal of Medical Research 2006;0(12):-
Objective To study the relationships between serum IL-18 and IL-18BP and the development,metastasis,curative effect and prognosis of primary liver cancer.Methods There were total 49 cases patients,of which 28 cases primary hepaticcarcinoma(PHC)and 21 cases liver cirrhosis(LC),and 18 cases heathy people.Their serum levels of IL-18 and IL-18BP were determined by using an ELISA assay and comparation.Results The serum IL-18 in PHC was significantly lower than that in LC and controls;the serum IL-18BP in PHC was significantly higher than that in LC and controls;the IL-18 and IL-18BP in LC were significantly higher than those in controls(P
2.The Clinical Study of Treating Skin T-lymphoma with Domestic Interferon(Sainuojin) and CHOPP-regimen
Chengnong GUAN ; Shujun LI ; Liangzhen CAI ; Qilian LIANG
Journal of Medical Research 2006;0(04):-
Objective To discuss the curative effects and side-effects of combining low-dose domestic interferon(sainuojin)with CHOPP-regimen in treating skin T-lymphoma.Method During the period June 1996 to June 2008,46 cases patient with skin T-lymphoma were treated by low-dose domestic interferon(sainuojin)and CHOPP-regimen,and all patient were received four cycle chemotherapy at least.And the usage was as follows:Sainuojin 3?106U/d,im,d1~21;CTX 600mg/m2,iv,d1;ADM 50mg/m2,iv,d1;VCR 1.4mg/m2,iv,d1;Predinisone 90 mg/d,PO,d1~5;PYM 8mg/d,im,d1,3,5,and every 3 weeks repeat.At the same time,the place of skin lesion was daubed with hydrochloric acid nitrogen mustard once everyday.Results CR 23 cases,PR 16 cases,NC 7 cases.The effective rate was 84.78%.The maximum time of survivorship was 11.6 years;the average survivorship time was 8.9?0.56 years;and the mostly side-effects were arrest of bone marrow and fever.Conclusion The curative effects of combining low-dose domestic interferon(sainuojin)with CHOPP-regimen in treating skin T-lymphoma were confirmed,and the side-effects were small.It is good for clinical popularization and application.
3.Three-Dimensional Ultrasonography in Obstetrics: the Clinical Value
Huixiong XU ; Qingping ZHANG ; XianTao XIAO ; Yuqing ZHOU ; Liangzhen WEN ; Jianping XU ; Min CAI
Journal of Huazhong University of Science and Technology (Medical Sciences) 2001;21(1):38-41,47
To investigate the clinical value of three-dimensional ultrasonography (3DUS) in obstetrics, various 3DUS rendering methods including surface mode, transparent mode and multiplanar mode were employed to scan 30 fetuses in second and third trimester by using the transabdominal volume transducer. The results showed that surface mode could vividly demonstrate the surface morphologic features of the fetuses, as well as the stereo-shape and the spatial relationship among the surface structures. The face, limbs, umbilical cord and outer genitalia of the fetus could be well displayed by surface mode. Transparent mode could reveal the bony structures under the surface, such as ribs, vertebrae, crania, etc. The result was not affected by the sophisticated curvature of these bony structures and the success rate was up to 100 %. When rendered by multiplanar mode, the region of interest (ROI) could be viewed from different directions. It should be concluded that 3DUS could serve as a supplement to two-dimensional ultrasonography (2DUS). 3DUS might play an important role in prenatal diagnosis and enhance the diagnostic confidence level of the physicians.
4.Three-Dimensional Ultrasonography in Obstetrics: the Clinical Value
Huixiong XU ; Qingping ZHANG ; XianTao XIAO ; Yuqing ZHOU ; Liangzhen WEN ; Jianping XU ; Min CAI
Journal of Huazhong University of Science and Technology (Medical Sciences) 2001;21(1):38-41,47
To investigate the clinical value of three-dimensional ultrasonography (3DUS) in obstetrics, various 3DUS rendering methods including surface mode, transparent mode and multiplanar mode were employed to scan 30 fetuses in second and third trimester by using the transabdominal volume transducer. The results showed that surface mode could vividly demonstrate the surface morphologic features of the fetuses, as well as the stereo-shape and the spatial relationship among the surface structures. The face, limbs, umbilical cord and outer genitalia of the fetus could be well displayed by surface mode. Transparent mode could reveal the bony structures under the surface, such as ribs, vertebrae, crania, etc. The result was not affected by the sophisticated curvature of these bony structures and the success rate was up to 100 %. When rendered by multiplanar mode, the region of interest (ROI) could be viewed from different directions. It should be concluded that 3DUS could serve as a supplement to two-dimensional ultrasonography (2DUS). 3DUS might play an important role in prenatal diagnosis and enhance the diagnostic confidence level of the physicians.