1.The research on the assessment methods of residents/specialist training
Liangyuan TANG ; Hongyan CHEN ; Guosheng REN ; Mingzhao XIAO
Chinese Journal of Medical Education Research 2003;0(02):-
Our hospital has set up a relatively complete assessment methods after nearly 10 years of residents/medical specialist training, including the day-to-day assessment, periodic assessment,comprehensive assessment,and completed the corresponding management evaluation.
2.The exploration of social residents (medical specialists) programmed education
Tianyou LUO ; Hongyan CHEN ; Hongmin ZHOU ; Liangyuan TANG ; Guosheng REN
Chinese Journal of Medical Education Research 2003;0(02):-
Residents(medical specialists)programmed education is an important aspect to fulfill the post-graduated medical education. It can remedy the clinical practice of young doctors,which ac-cords with the trend of international medical education .This article is to give advice for the resi-dents (medical specialists)programmed education according to the work and existing problems in our hospital.
3.Researches on the medical english ability in the residency training project
Hongyan CHEN ; Tianyou LUO ; Mingzhao XIAO ; Liangyuan TANG ; Guosheng REN
Chinese Journal of Medical Education Research 2003;0(04):-
We have established the model of English ability training on the residency training project,and have provided the systematic training plan to 29 residents who were employed in 2005.This paper summarizes the effect and points out the further reform perspectives.
4.The Practices of the New Teaching Modes in the Cardiopulmonary Resuscitation Training for the Standardized Training Residents
Jinglun LIU ; Fachun ZHOU ; Mingchao XIAO ; Hongyan CHEN ; Qiong LIU ; Liangyuan TANG
Chinese Journal of Medical Education Research 2006;0(09):-
Objective:To analyze and evaluate the teaching effect of the Problem-Based Learning and intelligent simulation training in emergency medicine.Methods:Based on Problem-Based Learning,129 residents of our hospital accepted the cardiopulmonary resuscitation training and test by intelligent simulation training.And their feedback questionnaires were analyzed.Results:After training,their abilities to deal with the cardiac arrest have made a great progress(P
5.Research progress on the role of microglia polarization in neuropathic pain
Jingjing CHEN ; Zhangsong NONG ; Liangyuan TAN ; Peipei YANG ; Yingye LIANG ; Hongliang TANG ; Kailong WANG
Tianjin Medical Journal 2024;52(9):1000-1003
Neuropathic pain(NPP)is a recurrent and intractable pain syndrome,and microglial polarization is closely related to it.Recent studies have shown that after cell polarization,M1 pro-inflammatory and M2 anti-inflammatory types could be formed,and M1 and M2 microglial cells are involved in NPP through the modulation of inflammatory responses.The two types of microglial cells have different roles in NPP,just like a double-edged sword.M1 pro-inflammatory type plays an injurious role in NPP through the release of pro-inflammatory factors and noxious substances,whereas M2 anti-inflammatory type plays a protective role by secreting anti-inflammatory factors.In this article,the role of microglia polarization on NPP are reviewed.
6.Fingerprint Establishment ,Content Determination and α-glucosidase Inhibitory Activity Study of Polysaccharide from Desmodium styracifolium
Xuanxuan CHENG ; Liangyuan CHEN ; Shijia ZHENG ; Xiaomin TANG ; Quan YANG
China Pharmacy 2020;31(2):183-189
OBJECTIVE:To estab lish the fingerprint ,analyze the monosaccharide composition and content ,investigate the inhibitory effects of the polysaccharide from Desmodium styracifolium on α-glucosidase in vitro . METHODS :Polysaccharide from D. styracifolium was prepared by water extraction and ethanol precipitation. After hydrolyzed by TFA and derived by PMP ,HPLC method was adopted to establish the fingerprint (using glucose peak as reference ),and analyze the constituent and content of monosaccharide. The content determination was performed on Phenomenex Luna C 18 column with mobile phase consisted of acetonitrile-0.05 mol/L potassium phosphate (pH adjusted to 6.8 with sodium hydroxide )in gradient elution at the flow rate of 0.8 mL/min. The detection wavelength was set at 250 nm,and column temperature was set at 30 ℃. The sample size was 10 μL. Using acarbose as control ,PNPG assay was used to investigate the α-glucosidase inhibitory activity of polysaccharide from D. styracifolium. RESULTS :There were 9 common peaks in HPLC fingerprints of 18 batches of samples ,and the similarity of 15 batches of samples was higher than 0.90. Totally 7 peaks were identified as mannose ,rhamnose,galacturonic acid ,glucose, galactose,xylose and arabinose. The contents of rhamnose ,galacturonic acid ,glucose,galactose and arabinose were 0.471-2.092, 1.379-8.919,2.560-35.679,1.194-6.905,0.566-4.158 mg/g,respectively. Based on rhamnose ,the molar ratios of the other four monosaccharides were 1.58-4.07,2.26-19.95,2.20-4.21 and 1.31-2.86,respectively. The inhibitory activity of polysaccharide from D. styracifolium on α-glucosidase increased with the increase of dose ,and the half inhibitory concentrations of it was 0.70 mg/mL, lower than 7.76 mg/mL of acarbose (positive control ). CONCLUSIONS :Glucose is the main component of D. styracifolium polysaccharide in different batches ,and the contents of monosaccharides are different. The polysaccharide from D. styracifolium have significant inhibitory activity on α-glucosidase,which is better than that of acarbose.