Since the outbreak of corona virus disease 2019(COVID 19), the epidemic has spread rapidly, which brings great challenge to the surgical diagnosis, treatment and management of lung neoplasm Sichuan International Medical Exchange &Promotion Association organized thoracic surgery experts to sum up experiences from experts in major hospital, and formulated the Guidance suggestion on surgical diagnosis, treatment and management of lung neoplasm during the outbreak of COVID-19 to provide references for thoracic surgeons.

Objective    To investigate the effect of surgical treatment on chest wall tuberculosis. Methods    A total of 407 patients with chest wall tuberculosis who met the inclusion and exclusion criteria from April 2008 to December 2017 in Chengdu Public Health Clinical Medical Center were enrolled. They were divided into two groups according to the time of admission: a control group (203 patients admitted from April 2008 to December 2012) treated with traditional focus debridement, including 135 males and 68 females, with an average age of 40.65±4.68 years, and an observation group (204 patients admitted from 2013 to 2017) undergoing complete focus debridement, including 139 males and 65 females, with an average age of 40.73±4.72 years. The general clinical data, perioperative related indexes, incision healing, incidence of complications and recurrence between the two groups were compared. Results    There was no significant difference in general clinical data, operation time, postoperative pain time, extubation time, hospital stay or recurrence rate between the two groups (P>0.05), but compared with the control group the grade A healing rate in the observation group was significantly higher and incidence of complications was significantly lower (P<0.05). Conclusion    Thorough debridement can achieve a better effect in the treatment of chest wall tuberculosis, and help to reduce complications and promote wound healing. It is suitable for clinical application.

Morgagni hernia is a rare form (accounting for 2%) of congenital diaphragmatic hernia. The traditional treatment for Morgagni hernia includes thoracotomy and laparotomy. However, surgical trauma limits its adoption. We reported the results of 2 patients with congenital Morgagni hernias in adults and described the operation methods of the patients. The 2 patients recovered uneventfully. No evidence of recurrence was found after 5 years follow-up. Laparoscopic repair for Morgagni hernia with mesh is applicable for obese, aged and bilateral Morgagni hernias patients.

Objective    To analyze the influencing factors for re-positive nucleic acid test in discharged corona-virus disease 2019 (COVID-19) patients in Chengdu, Sichuan Province, and to provide data support for the epidemics prevention and control. Methods    The clinical data of 660 discharged COVID-19 patients from January 23, 2020 to February 28, 2021 in our center were retrospectively analyzed. The patients were divided into two groups according to the reexamination of virus nucleic acid, including a negative group [549 patients, including 428 males and 121 females with a median age of 33.0 (28.0, 48.0) years] and a positive group [111 patients, including 76 males and 35 females with a median age of 39.0 (28.0, 51.0) years]. The clinical data of the two groups were compared. Results     The re-positive rate of the discharged patients was 16.82%. Univariate analysis showed that the re-positive rate of females was higher than that of males (χ2=4.608, P=0.032). The re-positive rate of confirmed patients was higher than that of asymptomatic infected patients (χ2=8.140, P=0.004). The re-positive rate of domestic patients was higher than that of imported patients (χ2=9.178, P=0.002). The counts of CD3+ (P=0.038), CD4+ (P=0.048) and CD8+ (P=0.040) T lymphocytes in the negative group were higher than those in the positive group. The binary logistic regression analysis showed that the clinical classification and CD8+ T lymphocyte count were independent risk factors affecting the recurrence of virility. Conclusion    The gender, origin, T lymphocyte subsets count and clinical type are the influencing factors for re-positive result, and clinical type and CD8+ T lymphocyte count are the independent influencing factors for re-positive result. Therefore, improving the immunity of infected patients, as well as early detection and timely treatment are effective means to reduce the re-positive occurrence.