OBJECTIVE To study drug resistance and distribution of infectious bacteria in lower respiratory tract among inpatients and outpatients and use the experience for reference of clinical application.METHODS Bacterial culture of the qualified sputum sample of patients who were admitted from Jan to Dec 2005 was done.The bacteria identification and drug sensitivity tests were done by ATB system.RESULTS Totally 687 strains of bacteria were isolated,the dominant were Gram-negative bacilli(81.5%).Among them,the Pseudomonas aeruginosa was 21.3%,the Acinetobacter baumannii was 19.8%,the Klebsiella pneumoniae was 14.3%,the Stenotrophomonas maltophilia was 16.6%,the Escherichia coli was 7.5%,and the others were 17.5%.The second pathogens were fungi(15.9%).The Gram-positive bacteria were the lowest ones.The results of drug sensitivity tests indicated,the imipenem was the most sensitive for Gram-negative bacilli except the P.aeruginosa and the M.stenotrophomonas(99.1% to 100.0%).For the P.aeruginosa,the amikacin was the highest one,and for the S.maltophilia,the highest was sulfamethoxazole-trimethoprim.CONCLUSIONS The dominant pathogenic bacteria in lower respiratory tract in our area are Gram-negative bacteria.For the same antimicrobial agent,different bacteria have a different sensitivity.We should select the antibiotic according to the results of drug sensitivity test.

Objective To explore how to perform effective health management for the metabolic syndrome(MS) in the health examination center. Methods A total of 153 subjects diagnosed with MS and the same number of healthy controls were analyzed. All patients received health management for 12 months and an impact evaluation was conducted. Results Waist circumference, IBM, SBP, DBP, blood lipids of MS group were remarkably higher than those in normal control group, and there was statistical significance (P

Objective To evaluate the relationship between body mass index (BMI) and blood pressure,blood glucose,lipid profiles and blood uric acid in healthy populations in Hefei of Anhui province.Methods A total of 3 640 healthy adults were enrolled to analyze the relationship between BMI and blood pressure and serum levels of lipid profiles,uric acid and glucose.Results The mean BMI of the subjects was (25.5±2.8) kg/m2 (men vs women:(26.3±2.5) vs (23.9±2.8) kg/m2).BMI showed a significant difference in different age groups (P＜0.05).Different BMI subgroup had statistically significant difference in blood pressure,glucose,lipid profiles and uric acid.In different gender and age groups,BMI,blood pressure,glucose,blood lipid and uric acid were found to be significantly different.Conclusion The prevalence of obesity and overweight is high in our health check-up populations.It should be important to prevent and control hypertension,high blood glucose,high blood uric acid and other chronic diseases.

The principles of balance, randomization, control and repetition, which are closely related, constitute the four principles of scientific research. The balance principle is the kernel of the four principles which runs through the other three. However, in scientific research, the balance principle is always overlooked. If the balance principle is not well performed, the research conclusion is easy to be denied, which may lead to the failure of the whole research. Therefore, it is essential to have a good command of the balance principle in scientific research. This article stresses the definition and function of the balance principle, the strategies and detailed measures to improve balance in scientific research, and the analysis of the common mistakes involving the use of the balance principle in scientific research.

Objective To study the cause, prophyl ax is and management of the complications of laser treatment for varicose veins of the lower extremity. Method From Sep 2003 to Dec 2004, 52 patients (65 limbs) underwent endovenous ablat ion procedures. The laser was introduced into the vein to achieve venous occlusi on. Results Postoperative complications included ecchymosis in 12 cases, skin burn in 14 cases, saphenous nerve injury in 7 cases, thrombophlebitis in 3 cases, and subcutaneous fat liqu idation and infection in 2 cases. Most of the complications subsided after sympt omatic treatment in 2 to 3 weeks. Conclusion Most complications of laser treatment for varicose veins are transient and self-healing.

Objective To obtain optimum scheme on reaction system for randomly amplified polymorphic DNA(RAPD) of Pseudomonas aeruginosa. Methods The optimum reaction systems of RAPD were obtained by single factor design and response surface design(RSD). Results The multiple optimum reaction systems caused by effect of interaction on multifactor were observed in single factor design, and the concentrations of key components of the optimum reaction system with good stability obtained by response surface design were 2.0 mmol/L of Mg 2+ , 0.5 ?mol/L of primer and 0.5 ng/?l of template. Conclusion To optimize the reaction system of RAPD, RSD is simpler, more scientific, and more reasonable than single factor design.