1.The advantages of ophthalmology and blindness prevention in health reforms.
Ophthalmology in China 1993;0(01):-
The primary eye care service is still absent in most of primary medical organizations in present China.Since imaging examinations provide main contribution to the diagnosis of eye diseases,ophthalmology and blindness prevention have technical predominance and requiring market in the field of telemedicine or e-healthy.We have explored different paradigms of blindness prevention according to variable levels of the region economy and medical conditions.In the urban community,the paradigm for preventable blindness has been adopted,and however,in the rural areas,the paradigm for curable blindness has been taken.It should be advocated to combine the primary eye care with the primary healthy care.It is in favor of sharing information,enhancing efficiency,improving quality, as well as entire orientation management to carry out digitalized ophthalmology regional cooperative medical service.Moreover,governmental leading function and policy sustaining are needed to complete the reform.
2.Study on Influence of EPO on Rabbits' TNF-?,IL-6,IL-10 and MDA with Blood Loss Shock and Endotoxemia
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To explore the rabbits' lipid peroxidation and cytokine level change caused by endotoxemia,use EPO for intervention.[Method]Bleed rabbits femoral for shock,after coming to,make injection of endotoxin,two beatings make dysfunctional multi-organs model;randomly divide 24 healthy rabbits into control group(1),2-beating group(2),EPO group(3),8 in each;take blood for testing indexes of TNF?,IL6,IL10 and MDA.[Result]Group 2 was higher than other groups on MDA level,group 3 less than group 2;group 2 was much higher than other 2 groups on TNF?,IL6 and IL10,group 3 less than group 2.[Conclusion]The cytokines and lipid peroxidation participating in the course of multi-organ injury caused by blood loss shock and endotoxemia can be reduced by EPO.
3.Protocol of glaucoma guideline summary
Ophthalmology in China 1994;0(02):-
Prevention and management of glaucoma is a priority task in the second phase of WHO " Vision 2020" project. In order to popularize the knowledge of glaucoma guideline, the author compiles the protocol of glaucoma guideline summary after referring to those deriving from American Academy of Ophthalmology, European Glaucoma Society, and South East Asia Glaucoma Interest Group. The guideline summary is easy to master and verify, and highlight the crucial points. The ISNT rule of neuroretinal rim is used to differentiate diagnosis between the physiological cup and glaucomatous rim lost. Foster's classification for primary angle-closure glaucoma (PACG) is used to select the treatment for PACG. It is emphasized that taking target pressure in the initial diagnosis, monitoring the optic discs and visual field loss in follow-up, and glaucoma screening by non-mydriatic digital fundus camera in the high risk population with screening diabetic retinopathy.
5.A Clinical Research of Self-made Jian-pi-hua-zhuo-xiao-yu Tang in the Treatment of Non-alcoholic Fatty Liver Disease
Journal of Zhejiang Chinese Medical University 2015;(5):358-360
Objection]To study the clinical effect of self-prescribed jianpihuazhuoxiaoyu decoction in treating the patients with non-alcoholic liver of fat. [Methods]45 patients were treated with self-prescribed Jianpihuazhuoxiaoyu decoction in treatment group and other 45 patients with Polyene Phosphatidylcholine Capsules and Ursodeoxycholic Acid. Observe the patients'body mass index(BMI),radiological changes,liver function(AST/ALT) and lipids(TG/TC/HDL/LDL). [Results] The total effective rates were 91.3%,82.6% respectively, compared with the control group,the treatment group significantly improved liver function,lipid content decreased,obesity weight was effectively controlled and reduced,sonogram also showed improvement in the texture of the liver,compared with control group there were significant differences(P<0.05),difference was statistically significant.
6.Change and significance of serum anti-brain antibodies in cardiopulmonary resuscitation patients
Chinese Journal of Postgraduates of Medicine 2014;37(28):40-42
Objective To observe the change of serum anti-brain antibodies after cardiopulmonary resuscitation,and investigate the clinical significance.Methods A total of 27 cases of cardiopulmonary resuscitation after cardiac arrest patients with success and survival more than 12 weeks were divided into two groups according to Glasgow Coma Scale (GCS) score:mild and moderate group with GCS score ≥ 8 scores (12 cases) and severe group with GCS score≤7 scores (15 cases).The serum anti-brain antibody levels at 3,7 days and 2,3,4,12 weeks after recovered in the spontaneous circulation (ROSC) was compared between two groups,and compared with control group (15 cases of healthy persons).Results The serum anti-brain antibody levels at 3,7 days and 2,3,4,12 weeks after ROSC were significantly higher than those in control group [(1.34 ± 0.23),(1.30 ± 0.27) kU/L vs.(0.28 ± 0.05) kU/L,(1.38 ± 0.33),(1.44 ± 0.30) kU/L vs.(0.28 ±0.05) kU/L,(1.44 ±0.31),(1.51 ±0.33) kU/L vs.(0.28 ±0.05) kU/L,(1.53 ±0.27),(1.67 ±0.36) kU/L vs.(0.28 ±0.05) kU/L,(1.72 ±0.25),(1.93 ±0.44) kU/L vs.(0.28 ±0.05) kU/L,(1.98 ±0.45),(2.15 ±0.52) kU/L vs.(0.28 ±0.05) kU/L],and there were significant differences (P< 0.01).The serum anti-brain antibody levels in severe group were significantly higher than those in mild and moderate group,and there were significnat differences (P < 0.05).Conclusions The serum anti-brain antibody levels after cardiopulmonary resuscitation rise significantly.Anti-brain antibody may be used as a biochemistry marker to judge degree and prognosis of brain injury with patients after cardiopulmonary resuscitation.
7.Function of P2 receptors in skeletal system and inflammatory disease of bone
Changshui XU ; Shangdong LIANG
Chinese Pharmacological Bulletin 1986;0(04):-
Extracellular purine and pyrimidine nucleotides produce the biologic effects involved in activating P2 receptors.P2 receptors are divided P2X and P2Y receptor subtypes.There is molecular and functional evidence for widespread expression of P2X and P2Y receptor subtypes in osteoblasts,osteoclasts and cartilage cells of the skeletal system.Working through P2 receptors,ATP and other nucleotides released into the bone microenvironment regulate formation and activity of bone and cartilage,including development,growth,turnover and repair of biological functions.The release of nucleotides is increased under inflammatory conditions,and localized ATP release could stimulate formation and activation of osteoclasts.Abnormalities of bone remodelling can produce a variety of skeletal disorders.P2 receptors play an important role in the inflammatory disease of bone.
8.Challenge and strategy for prevention of myopia in China
Ophthalmology in China 2006;0(06):-
The current prevalence of myopia has been as high as 27.65%~53.80%among adolescents in Chinese schools.The major reasons are too much near-work activity and lack of outdoor activity for a long time.In order to reduce the prevalence of myopia in Chinese adolescents,we suggest that Chinese students should have 3.5 hours outdoor activity everyday,including 30 minutes travel between home and school,1 hour outdoor activity between classes,1 hour outdoor sport class at school,and 1 hour outdoor activity after school.
9.A new method of cataract imaging evaluation
Ophthalmology in China 1994;0(02):-
Photography of slit-lamp biomicroscopy combined with retro-illumination photography is the gold standard in cataract evaluation. However the application is limited due to its complexity and low efficiency. We introduce digital non-mydriatic fundus photography as a new method for cataract screening in patients with visual impairment,which might play an important role in screening low vision and blindness caused by cataract. Two distinguished benefits are found in this method including compatibility for tele-diagnosis,and integration with screening of glaucoma and diabetic retinopathy. Cautions should be made on the photographs in which media opacity derived from other than cataract or low quality photos due to small pupils.
10.Analysis of Labeled Items in Package Inserts of 51 Kinds of Ointment for External Use
China Pharmacy 2017;28(16):2286-2288
OBJECTIVE:To provide reference for reasonably designing package inserts of ointment for manufacturers. METH-ODS:According to items included in Management Regulation for Package Insert and Label and Specification for Chemicals and Bi-ological Products for Treatment,labeled items in package inserts of 51 kinds of ointment for external use during Jan.-Jun. 2016 in our hospital were analyzed. RESULTS:Among the 51 kinds of ointment,39 were domestic varieties and 12 were imported variet-ies. In the package inserts of 39 domestic varieties,items with lower labeling rates were overdose,pharmacokinetics,use guid-ance,pharmacology and toxicology,with labeling rates of 2.6%,5.1%,15.4%,28.2%;while the labeling rates of imported vari-eties were 16.7%,83.3%,75.0%,100%. Compared with package inserts of imported ointment,composition,dosage and usage, adverse reactions,contraindications,precautions,drug interactions,medication for special populations were not enough detailed in domestic ointments. CONCLUSIONS:It is suggested that manufacturers consult medicine experts, list all auxiliary materials through Management Regulation for Drug Description and Label,refine and improve the labeling contents of dosage and usage,ad-verse reactions,precautions,medication for special populations,pharmacology and toxicology,overdose,etc. In addition,admin-istrative departments should strengthen the regulatory approval efforts.