1.Problems and Countermeasure of IntroducingMedical Social Workers to Hospitals
Chinese Medical Ethics 2016;29(4):665-667
In China, health care system is not perfect,the trust is lack between doctors and patients. Introdu-cing medical social workers to hospitals is to manage social resources as a whole, optimize medical treatment service process,enhance the quality of medical service, and relieve the pressure of doctors and nurses. Under this back-ground, this paper gave an overview of the medical social work and its contents. Then, it analyzed the necessity of introducing medical social workers to hospitals and pointed out the existing plight of medical social work. Finally, it put forward the suggestions and countermeasures to promote medical social work.
2.Effect of two different surgeries on corneal endothelial cells in grade Ⅱ - Ⅲ lens nucleus
International Eye Science 2017;17(10):1878-1882
AIM: To compare the effect of small incision extracapsular cataract extraction and phacoemulsification on corneal endothelial cells and explore the differences between these two most commonly used surgeries for grade Ⅱ-Ⅲ lens nucleus. · METHODS: Retrospective study. We retrospectively evaluated the data of age-related cataract patients who had completed surgery in our hospital between June 2013 and December 2015. There were 84 eyes of 84 patients. The corneal endothelial cell density of all the patients were greater than 2000/mm2 and lens nucleus were gradeⅡ- Ⅲ. The patients were divided into manual small incision cataract surgery ( MSICS ) group and phacoemulsification ( Phaco ) group. MSICS group included 42 cases (42 eyes) and Phaco group included 42 cases ( 42 eyes ) . Postoperative evaluations were performed at 1d, 1wk, 1mo and 6mo and included uncorrected visual acuity ( UCVA ) , corneal endothelial cell density and the proportion of hexagonal cells. · RESULTS: There were no statistically significant differences of the two groups in preoperative basic data, UCVA, corneal endothelial cell density and the proportion of hexagonal cells, nuclear classification. The postoperative UCVA were significantly improved in both groups (x2=148. 01, P<0. 001; x2=165. 97, P<0. 001). The postoperative UCVA were on the rise as time goes on. The postoperative corneal endothelial cell density was obviously reduced in both groups compared with the preoperative (F=37. 74, P<0. 001; F=24. 56, P<0. 001). The proportion of hexagonal cells in Phaco group was declined at 1d (P=0. 002) after the operation and returned to baseline by 1wk (P=0. 894) after surgery. There was no significant difference between the two groups in UCVA, corneal endothelial cell density and the proportion of hexagonal cells at each observation point (P>0. 05). ·CONCLUSION: Manual small incision cataract surgery and phacoemulsification can indiscriminately improve UCVA and decrease the density of corneal endothelial cells. However, the change of hexagonal cells proportion was not obvious. These two surgeries for cataract patients with corneal endothelial cell density greater than 2000/mm2 , grade Ⅱ-Ⅲ lens nucleus have similar efficacy and safety.
3.Therapeutic observation on lung-clearing and spleen-strengthening tuina in children with exogenous cough
Journal of Acupuncture and Tuina Science 2020;18(3):225-230
Objective: To observe the clinical efficacy of lung-clearing and spleen-strengthening tuina on exogenous cough in children. Methods: A total of 77 children with exogenous cough that met the inclusion criteria were randomly divided into a treatment group and a control group according to the random number table, with 39 cases in the treatment group and 38 cases in the control group. The routine lung-clearing manipulation was used in the two groups, while the spleen- strengthening manipulation was added in the treatment group. Both groups were treated once a day, 5 times as a course of treatment. After one course of treatment, the symptom score and clinical efficacy were observed. Results: There were one dropout in the treatment group and 2 dropouts in the control group. Therefore, a total of 74 cases were finally included in the analysis, with 38 cases in the treatment group and 36 cases in the control group. After treatment, there was a statistically significant difference in cough score between the two groups (P<0.05). There was a statistically significant difference in the score of poor appetite between the two groups (P<0.05). After treatment, the total effective rate was 89.5% in the treatment group versus 75.0% in the control group, showing a statistically significant difference (P<0.05). Conclusion: The therapeutic efficacy of lung-clearing spleen-strengthening manipulation is better than that of lung-clearing tuina manipulation alone for children with exogenous cough; regulating spleen and stomach can improve the curative efficacy of exogenous cough in children.
4.Molecular epidemiological characteristics of metallo-β-lactamase-producing Pseudomonas aeruginosa from Changsha
Jingmin WU ; Mingxiang ZOU ; Jun LI
Chinese Journal of Infection Control 2016;15(7):447-451
Objective To investigate the genotypes and epidemic of metallo-β-lactamase-(MBL )-producing Pseudomonas aeruginosa (P .aeruginosa)in Changsha.Methods P .aeruginosa isolated from seven comprehensive hospitals in Changsha were collected and performed identification and antimicrobial susceptibility testing,pheno-types of MBL were detected with EDTA-disk synergy test and E-test,genotypes were determined by polymerase chain reaction (PCR),homology analysis were conducted by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR).Results Preliminary screening by EDTA-disk synergy test and E-test showed that only 10 of 81 iso-lates were strong positive;PCR result showed that 18 isolates were positive for MBL,11 of which were IMP-9-type MBL,1 was IMP-1-type,and 6 were VIM-2-type.SIM,SPM,GIM,and NDM-1-types were not found.ERIC-PCR showed that 12 strains of IMP-producing P .aeruginosa has multiple types,6 VIM-2-producing strains were of the same type.Conclusion IMP-9 and VIM-2 are main genotypes in P .aeruginosa in Changsha.
5.Clinical and coronary characteristics of women drug abuse patient with acute myocardial infarction
Chongqing Medicine 2014;(30):3999-4001
Objective To study the clinical and coronary characteristics of drug abuse women patients with acute myocardial in-farction .Methods Data of 70 women patients ,who were diagnosed with acute myocardial infarction(AMI)and underwent emergent coronary angiography in department of jurisdiction ,Guangdong Provincial Corps Hospital ,Chinese People′s Armed Police Force from January 2006 to July 2012 ,were analyzed .Results 66 of 70 were ST-segment elevated myocardial infarction ,4 were non-ST-segment elevated myocardial infarction ;67 of 70 were obstructive lesion ,underwent percutaneous coronary intervention .With the drug abuse time prolonging ,the combining risk factors increased ,the occurrence rate of AMI increased(P<0 .05) .Data of coronary angiography showed that the culprit vessels of most AMI patients with different drug abuse time were single vessel lesion ,which was significantly higher than the rate of three vessel and main stem .the most common culprit vessel was the left anterior descending artery ,followed by the right coronary artery and left circumflex artery lesion .three vessel and main stem lesion were short in pa-tients of drug abuse time <5 years ,with the prolonging of drug abuse time ,three vessel and main stem lesion increased .There was 1 death example in prison and 5 re-admission fore agnia during the follow-up .Conclusion Most AMI in drug abuse women patients with acute myocardial infarction is STEMI .Single vessel and obstructive lesion is the most common .The most common culprit ves-sel was the left anterior descending artery .Most female patients were complicated with congenital coronary malformation or autoim-mune disease .With the prolonging of drug abuse time and increasing of combining risk factors ,the rate of AMI increases .
6.Differentially expressed genes of hypertrophic scar and normal skin
Zhenxiang WANG ; Jun WU ; Shirong LI
Chinese Journal of Medical Aesthetics and Cosmetology 2001;0(03):-
Objective To screen the differentially expressed genes between hypertrophic scar of burn and normal skin using gene microarray, to find out the genes of significantly different-expression and to analyse the roles of them in development of hypertrophic scar. Methods The total DNA and RNA from 4 hypertrophic scar samples and 4 normal skin were isolated and purified to mRNA by oligotex. They were reversely transcribed to cDNA with the incorporation of fluorescent dTUP to prepare the hybridization probes. Then, the mixed probes were hybridized to the cDNA chip and scanned for the signals and found differences between scar and normal skin. Results Among 4000 target genes, there were 378~451 genes once and 114~152 third times significantly different between hypertrophic scar and normal skin and 97 different-expressed genes in all 4 cases. Conclusions There are differences of gene expression between hypertrophic scar and normal skin screened by microarray. As the scanned cases increase, the common differentially-expressed genes become less and less, which may involve in the development of hypertrophic scar.
7.Macroporous PHBV matrices for cartilage tissue engineering
Jun WU ; Junying SUN ; Haiyan LI
Orthopedic Journal of China 2006;0(13):-
[Objective]To investigate the possibility of using poly(hydroxybutyrate-co-hydroxyvalerate)(PHBV)as scaffolds for cartilage tissue engineering and to compare the engineered cartilage generated in vitro with those in nude mice modles.[Method]PHBV porous scaffolds were fabricated using a compression moulding,thermal processing and salt particulate leaching methods.Chondrocytes isolated from articular cartilage were seeded into porous PHBV scaffolds.After incubation for 2 weeks in vitro,chondrocytes-PHBV constructs were implanted subcutaneously in the dorsum of athymic nude mice.Control groups were established by subcutaneous implantation of PHBV alone.The implants harvested after in vivo incubation of 4 and 8 weeks and cell-scaffolds cultured in vitro for 6 and 10 weeks were respectively examined histologically.Chondrocytes cultured for 3,7 and 14 days on the scaffolds were examined by SEM.[Result]SEM showed that chondrocytes could aggregate and synthesize extracellular matrix on PHBV scaffolds.Both specimens harvested from nude mice and those cultured in vitro demonstrated new cartilage formation,while characteristics of the engineered cartilage generated in vivo were more typical.Those from control groups showed no cartilage formation.[Conclusion]PHBV can be used as scaffolds for cartilage tissue engineering and nude mice modle seems to facilitate chondrogenesis compared with that in vitro system.
8.Expression of MT-1 and MT-2 Genes in Liver of Chronic Exposure to Inorganic Arsenate Mice
Journal of Environment and Health 2007;0(10):-
Objective To investigate the effect of MT-1 and MT-2 in liver damage in chronic inorganic arsenate exposure mice and to explore the mechanism of arsenic-induced liver damage. Methods The male Kunming mice were randomly divided into control and exposed groups. The control group was given ordinary feed and tap water. The exposed group was given ordinary feed and 300 mg/L of sodium arsenite solution by drinking water. After 10 months of treatment, the activity of serum alanine aminotransferase (ALT), aspartate aminotransferase(AST) and globulin (Glb) content were determined. The total RNA was extracted by the TRIzol-phenol-chlorofor-method from the liver tissue. The quantity of the RNA was determined by spectrophotometry and its purity was judged at a ratio of A260/A280. Then real-time PCR(RT-PCR) was used to measure the mRNA expression of MT-1 and MT-2. Results Compared with the control group, serum ALT, AST activity and Glb content were higher and the MT-1 and MT-2 mRNA content was lower in the exposed group (P
9.The radiation and intervention management system based on VFOXPRO
Chinese Journal of Hospital Administration 1996;0(02):-
Objective The paper gives an account of the composition, functions and major techniques used in designing the total management system of radiation and management. Materials mid Methods With the use of the Windows as the development platform, VFOXPR06. 0 was employed to design the application software for tha management of radiation and intervention record data and intervention materials. Results The software can be used for registration, the disposition of diagnostic reports, the retrieval of patient information, the browsing of DICOM format images, statistical analysis and the management of intervention materials. Conclusion Easy to operate and fast in data handling, the system is of great practical value and is worthy of being widely spread.
10.Case of Meige syndrome.
Chinese Acupuncture & Moxibustion 2014;34(12):1178-1178