The antiarrhythmic actions of ZnSO4 (Zinc) were studied in ex-perimental arrhythmias models. ZnSO4 10mg/kg(iv) significantly coun-teracted the arrhythmias, induced by aconitine or BaCl2 rats.It was shown to shorten the duration of arrhythmias induced by chloroform-epinephrine in rabbits. In mice, ZnSO4 20 ?g/10g(ip) decreased the incidence of ventricular fibrillationbychloroform. However, ZnSO4 did not decrease the incidence of CaCl2-induced , venticular fibrillation, the threshold and lethal doseofouabain in producing ventricular permature beats, ventricular fibrillation in guinea pigs.

Zinc sulfate 0.1mmol/L inhibited the frequency dependent positive staircase phenomenon on isolated guinea pig atria. Ten min after adding zinc sulfate 0.1 mmol/L, the contractility of the left atrium decreased. The needed concentration of epinephrine inducing automaticity was increased and the functional refractory period(FRP) was prolonged from 192?5 ms to 247?4 ms ( P

The effects of Na_2MoO_4 on experimental ventricular arrhythmias and isolated guinea pig atria are reported. Iv Na_2MoO_4, 8 mg/kg was found to increase the tolerant dose of ouabain to produce ventricular permature beats, ventricular tachycardia and ventricular fibrillation in guinea pigs. Na_2MoO_4 significantly counteracted the ventricular arrhythmias induced by BaCl_2 and aconitine in rats. Na_2MoO_4 10 ?g/10 g ip decreased the incidence of ventricular fibrillation by chloroform in mice, Na_2MoO_4 10 mg/kg did not produce antagonistic effect on the arrhythmias induced by chloroform-adrenaline in rabbits. Na_2MoO_4 0.1 mmol/L inhibited contractility of isolated guinea pig atria, prolonged the functional refractory period and makedly inhibited the frequency-dependent positive staircase phenomenon and the post-rest potentiation.

Objective To explore the correlation between metabolic syndrome (MS)and benign prostatic hyperplasia (BPH) and the drug treatment of BPH.Methods 300 cases of BPH patients treated between May 2011 to June 2012 in our hospital and Tong-Hai County hospitals of traditional Chinese medicine were included.The patients were divided into observing group (n=100) and control group (n=200).The observing group was treated with 5-alpha reductase inhibitors (finasteride).100 patients in control group-1 were treated with alpha-1 receptor blockers (terazosin).100 patients in control group-2 were treated with finasteride and terazosin.The changes of symptom scores,maximum urinary flow rate and prostate volume at month 3,month 6 and at end of a year after the treatment were compared among all groups.Results In 300 cases of BPH patients,there are 256 cases (85.3％) of MS+BPH,and 44 cases (14.7％) of simple BPH,with no statistically significant difference between the two groups in age and total cholesterol level (both P＞0.05).Among 256 cases of MS+ BPH,127 cases (49.6％) had diabetes,174cases (68.0％) had hypertension,85 cases (33.2 ％) had hypercholesterolemia or high triglyceride.The body mass index,blood pressure,fasting plasma glucose,IPSS gland volume were significantly higher (P＜0.05),and the maximum urinary flow rate was significantly lower in MS+BPH group than in the pure BPH group (P＜0.05).Prostate volume was positively correlated with age,body mass index,systolic blood pressure,fasting plasma glucose.IPSS score were positively correlated with age,body mass index,fasting blood glucose,total cholesterol.Maximum urinary flow rate were negatively correlated with age,fasting glucose,total cholesterol.At month 3 after treatment,the symptom score,maximum urinary flow rate were better in both of control group 1 and 2 than in the observation group (both P＜0.05).At 6 months after treatment,there was no statistically significant difference between the two groups in the symptom score,maximum urinary flow rate (both P＞0.05),while prostate volume was smaller in the observation group than in controls group 1 (P＜0.05).After a year of treatment,there were statistically significant differences in above indicators between the observe group and control group-1 (all P＜0.05),and had no statistically significant difference between the observe group and control group 2(all P＞0.05).Conclusions Most patients with BPH are suffering from MS at the same time.Body mass index,blood pressure,blood sugar,prostate volume,IPSS are higher in MS+BPH patients than in patients only with BPH.MS may affect the incidence and prognosis of BPH.Finasteride combined with terazosin can be used within 6 months,and finasteride can be used alone after 6 months of the drug therapy.

This article puts forward the basic contents,the necessity and meanings of carrying out the information literacy education for the medical university students.It points out some measures in the information literacy education.

Autoimmune Diseases ; chemically induced ; Female ; Humans ; Interferons ; adverse effects ; Purpura, Thrombocytopenic, Idiopathic ; chemically induced ; Young Adult

Since cardiopulmonary resuscitation(CPR)guidelines was constituted in 1974,it was adopted many times.The American Heart Association,in collaboration with the International Liaison Committee on Resuscitation(ILCOR),adopted new CPR science guidelines in January,2005.This article gives a short introduction of CPR,and showes the progress of several editions.

The vaccine based on dendritic ceil has becomes a new research focus in the biotherapy of breast cancer. And the ways of making the vaccine are vary and no one approach has been shown to be superior to another.