One hundred mandibles of adult Chinese male unearthed in Shanghai without missing teeth, alveolar bone resorption or/and malposition of teeth were studied. Our data showed that the location of the mental foramen below the apex of the lower second premolar was the most common. Our results were compared with those of other investigators. The Clinical significance of iden.tifying the anatomical location of the mental foramen in dental practice is discussed

We tried to clarify the role of oxygen radicals [released from granulocytes stimulated by phorbol myristate acetate (PMA) in rat acute lung injury. It was found that DNA strand-break damage (DSBD) in peripheral white blood cells was significantly increased 40 min after injection of PMA. DSBD in lung tissue of rats treated with PMA was also markedly increased. The PMA-treated rats showed significantly higher lipid-peroxide (LPO) level in plasma and lung hemogenate than the controls. These results suggest that determination of DSBD, a simple and sensitive indicator for oxygen radical damaging, might be useful in the diagnosis of adult respiratory distress syndrome, when it is used together with measurement of plasma LPO.

We separated viable tumor-infiltrating lymphocytes (TIL) and reginal lymphaden lymphocytes (RNL) from 37 cases solid human tumors and their reginal lymphadens, by means of combing mechanical and enzymatic digestion and discontinuous density gradients. The total cell recovery were 0.42-78.4?10~6 per gm tumor and 8.8-194?10~6 per gm lymphaden. The purity TIL and RNL fraction were 61.1?15.4% and 82.5?8.2%, respectively. Activated TIL, PBL, RNL and splenic cell (SPC) by rIL-2 expanded 2.58?1.05?10~5 -fold, 2.7?2.6?10~3-fold, 8.25 ?2.85?10~6-fold and 5.64 ? 2.51?10~3-fold in an average of 39.2?11.2 days. Total cell numbers in RNLs and 26/37 (70.3%) of TILs were up to 10~(10).

OBJECTIVE:To establish a HPLC method for the determination of Glycyrrhizic acid in Jiaweihuoxiangzhengqi pill.METHODS:The analysis was performed on a Varian C18(250mm?4.6mm,5?m)column at room temperature with a mobile phase consisted of acetonitrile-methanol-0.2mol?L-1 ammonium acetate-acetate(56∶9∶34∶1)at a flow rate of 0.9mL?min-1.The detection wavelength was set at 254nm.RESULTS:Good linear relationship was achieved when the detection concentration range of Glycyrrhizic acid was 10～50?g?mL-1(r=0.999 5).The average recovery was 99.06%(RSD=0.58%,n=9).CONCLUSION:The method was simple,rapid,sensitive and reproducible,which can be used for the quality control of Jiaweihuoxiangzhengqi pill.

Biochemistry is one of the important basic courses.There are some exploration and thinking on biochemistry teaching reform from teaching features of medical education,the application of teaching basic principles and the designing of teaching regulation forms.

Objective To investigate the human papillomavirus (HPV)E6/E7 mRNA detection used in cervical cancer screen-ing.Methods In the study,160 patients treated in gynaecology department of the hospital were enrolled,whose samples were col-lected for ultra-thin liquid-based cytology(thin prep cytology test,TCT).According to the TCT results,the patients were divided into 4 groups,including normal group(n=32),CINⅠ group(n=44),CINⅡ group(n=67),CINⅢ group(n=17).In addition to the CIN classification,according to the type of pathology the patients′groups were also devided.In different groups,the differences be-tween HPV E6/E7 mRNA and HPV DNA positive rate were compared respectively.The differences between HPV E6/E7 mRNA and HPV DNA levels among different pathology groups were also compared.Results In groups of different CIN grades and control group,the positive rate of HPV E6/E7 mRNA and HPV DNA test showed statistically diffrences (P <0.05 ).Compared among different pathologic groups HPV E6/E7 mRNA and HPV DNA levels were statistically significant (P <0.05).Conclusion In cer-vical cancer screening,HPV E6/E7 mRNA screening can be used as a screening method and its combined use with cytological meth-od would be helpful to improve the diagnostic accuracy.

Objective To study the effect of biofeedback electrical stimulation combined with pelvic floor muscle training in the postpartum rehabilitation treatment of pelvic floor function.Methods 320 puerperants who were rechecked at 42d after the delivery in our hospital from September 2011 to January 2013 were divided into two groups,patients in the observation group were treated with biofeedback electrical stimulation combined with pelvic floor muscle training ,patients in the control group were given without treatment intervention,then the pelvic floor muscle tension,vaginal muscle voltage and urinary incontinence rate of two groups at 3 month after the treatment were compared.Results The improvement of pelvic floor muscle tension and vaginal muscle voltage of observation group were significantly better than those of control group (<0.05),the urinary incontinence rate was significantly lower (<0.05) .Conclusion The biofeedback electrical stimulation combined with pelvic floor muscle training can effectively improve the pelvic floor muscle tension and decrease the urinary incontinence rate,so it can improve the life quality of puerperants.

Renal fibrosis is the final common pathway to all progressive renal disease.Studies have found that Wnt pathway exists in the process of renal fibrosis and plays an important role in the process of renal fibrosis.This paper reviewes the relation of wnt pathway and renal fibrosis.

Objective To evaluate the correlations of serum cardiac troponin T and serum uric acid levels in in aged patients with chronic congestive heart failure(CHF) and the effect of cardiac troponin T(cTnT) on the prognosis of the CHF. Methods 200 cases of congestive heart failure patients(Cardiac function NYHA class Ⅰ-Ⅳ) were enrolled for retrospective analysis and divided into four groups ,50 cases per group;randomly picked 50 cases of pantients with cardiac function NYHA class Ⅰ as a control group; and analyzed the relationship of serum uric (UA) and cTnT level and the occurrence of CHF. All the patients were arranged into normal group and higher group according to cTnT concentration. Cardiac events, including repeated or aggravated heart failure or cardiac death,in patients with increased cTnT during hospitalization were compared to those without it. Results In congestive heart failure group (Cardiac function NYHA class Ⅱ-Ⅳ) ,the cTnT and UA contents increased significantly than that in control group.Incidence of cardiac events was higher in patients with increased cTnT than without it (P ＜ 0.05). Conclusion The heavier the congestive heart failure, the blood uric acid and troponin T were more elevated, so they were closely linked with congestive heart failure, and were the factor for onset of congestive heart failure, and could be combined to evaluate the severity of heart failure in aged patients. The cTnT could predict the prognosis of the old patients with CHF.

BACKGROUND: Mental health is the most important internal resource that individual can depend on and also an important factor which affects the existence and development of individual. But there are few studies on the level and characteristics of mental health of female prisoners during serving a sentence.OBJECTIVE: To investigate the level and characteristics of mental health of the female prisoners in Shandong Province.DESIGN: Retrospective, cross sectional,multi-variable and sampling survey based on female prisoners.SETTING: Department of Technology in Shandong Police College.PARTICIPANTS: The investigation was completed in the Shandong Police College frotm January 2002 to March 2002.Totally 393 female prisoners from the Shandong Female Prison were selected with the grouping-sampling method to give the questionnaire and attend the investigation voluntarily,and the persons with definite mental disease were excluded.METHODS: The mental health items of female prisoners,including 9 factors such as somatization, obsessive-compulsion,sensitivity of human relations, depression, anxiety, hostility, phobia anxiety, paranoid ideation and psychosis,were explored with Symptom Checklist 90(SCL-90), and the judging standard of psychologic obstacle was whether the total scores of positive symptoms were 2 standard deviations more than those of the norm or not.And combined with the archives of the female prisoners and the questionnaire of self-editing item,relative data were collected. The uniform instructional words and the methods of filling in were explained to the female prisoners firstly,and then the answers of the questionnaire were written collectively.MAIN OUTCOME MEASURES: The mental health level and the psychological characteristics of female prisoners.RESULTS: 393 questionnaires were provided.There were 15 questionnaires excluded because more than 5 questions were missed in the paper or responsion consistency deviation appeared obviously after callback.378questionnaires were valid ,and the effective rate was 96.2%. ①The item numbers of positive reaction,total average score,toatal average score of positive symptoms of SCL of the prisoners were higher respectively than those of the norm of general group and reached the most significant level.The psychological problems of different degrees were widespread among them.②There were 372 female prisoners who had positive symptoms, and the detection rate was 98.41% ,which was more than that of positive symptoms in prisoners (40.6%).The significance of difference existed(x2=503.59,P ＜ 0.001).There were 84 persons who had psychologic obstacle in the female prisoners,and the detection rate was 22.2%,which was higher than that of in the general group (10.54%).The significance of difference existed (x2=54.128,P ＜ 0.001). ③The scores of 9 factors of SCL were all higher in the female prisoners than in the adult norm of the country,and reached the most significant degree. It showed that the obvious abnormality existed in the somatization, obsessive-compulsion, sensitivity of human relations, depression, anxiety, hostility, phobia anxiety,paranoid ideation and psychosis of the tested persons, and the ordering of them was sensitivity of human relations ＞hostility ＞obsessive obsessivecompulsion ＞depression ＞somatization ＞anxiety ＞phobia anxiety/paranoid ideation＞psychosis. Among the 9 factors,the average scores of obsessivecompulsion, sensitivity of human relations, depression,and hostility were greater than 2,and the symptomatic reaction of them was already above moderate. ④The detection rates of psychological problem or psychologic obstacle of the factors such as paranoid ideation, hostility, somatization,sensitivity of human relations and anxiety,etc.were higher,which indicated that these were the main psychological deviation contents.CONCLUNSION: Compared with the general group,the total level of mental health of female prisoners is lower, and the detection rate of psychologic obstacle and the degree of symptomatic reaction are obviously higher,and the psychological characteristics such as phobia anxiety, obsessive-compulsion,sensitive-suspiciousness, depression and hostility,etc are outstanding.