Objective To investigate the effect of desflurane on neuromuscular blockade of rocuronium Methods Thirty adult patients ,scheduled for selective surgery under general anesthesia, were randomly allocated to receiving intravenous propofol 4mg?mg -1 (group I,n=10),inhalation of 1MAC(6%) desflurane lasting 15 min (group Ⅱ,n=10) or 45 min(group Ⅲ,n=10) to maintain anesthesia,respectively Rocuronium 0 6 mg?kg -1 was given intravenously in group I following stable anesthesia , in group Ⅱ or group Ⅲ with the stable end tidal concentration of desflurane at 1MAC for 15 min or 45 min,respectively The onset time and degree of neuromuscular blockade were monitored with train of four(TOF) technique.Results The onset times of T 1 and TOF in group Ⅲ(1 3 and 0 8 min) were shorter than in group I(2 2 and 1 5 min)(P

Objective To select the acceptor ingredients of Streptococcus mutans protein in the whole saliva through the interaction between adhesion and saliva protein of Streptococcus mutans. Methods After activation and liquid culture of Streptococcus mutans strains of international standards, we took Su-bonding from liquid culture of bacteria secretion in the process of liquid culture by using chilled ethanol extraction. Then su-bonded components underwent electrophoresis analysis, content determination and antigen detection. We collected 15 with high carries and 15 with no carries. Two hours after eating, the whole non-irritating saliva was collected, electrophoresis samples were prepared after freeze-drying, and then stains were separated with SDSPAGE. Western blot detection was used for adhesive protein and Streptococcus mutans' antibody composition. Results The ingredients of Su-bonding secreted on the surface of Streptococcus mutans were obtained in the cultured saliva. There were at least six kinds of components in the extraction of Western blot detection, not limited to the three known kinds of proline-rich protein. Conclusion The adhesion of Streptococcus mutants can be bound with the proteins of saliva. It may be the material basis in Streptococcus mutants adhered to tooth surface.

Objective By investigating the quality and unreasonable prescription of traditional Chinese medicine in our hospital, to analyze the reason and thus put forward the solution and elevate the whole rational administration level in our hospital. Methods 3000 prescriptions prescribed in our hospital from April 2008 to April 2009 were randomly investigated. Select the unreasonable prescriptions and unreasonable use of medicines in a prescription for statistical analysis. Results There were 258 unreasonable prescriptions among spot-check 3000 sheets of prescriptions, reaching 8.6%. There were 633 unreasonable medications, including oversized or excessively small dosage, improper compatibility, repeated medications, etc. Conclusion There is the phenomena of unreasonable prescription in our hospital. Therefore, we should reinforce the management of prescribing medicines and enhance the level of reasonable medication.

In the present study the projections were traced from the red nucleus and the region of the griseum centrale mesencephali to the inferior olivary complex (IOC) by using the method of anterograde transport of the WGA-HRP in the cat. The results has led to the following conclusions: 1.Both injected regions have positive projections to the ipsilateral IOC. No labeled cells were found in the IOC. 2. The projections from the red nucleus to the IOC terminated in the dorsal lamina of the principal olive and the dorsal end of the caudal half of the medial accessory olive. The projections from the region of the griseum centrale mesencephali to the IOC terminated in the whole medial accessory olive, ventral lamina of the principal olive and the connecting part between the ventrolateral end of ventral lamina and dorsal lamina of the principal olive. The most heavily labeled regions were the dorsal lamina of the principal olive among the regions receiving projection from the red nucleus and the medial accessory olive among those receiving fibers from the griseum centrale mesencephali region, the other regions were more lightly labeled.3. Some labeled regions of the IOC in the present study overlapped with those regions receiving fibers from the spinal cord reported by others. In the present study the labeled area is more extensive than those reported in the literature.

Objective:To examine the changes of matrix metalloprotein as e-2 (MMP-2) and tissue inhibitors of matrix metalloproteinase-2(TIMP-2) in g ingival crevicular fluid(GCF) after periodontal initial treatment of adult perio dontitis pateins. Methods:42 teeth of 42 adult periodontitis pat eins and 42 teeth of 42 periodontal healthy subjects were included.GCF was samp led with filter paper strips by intra-pocket methed. Assays for MMP-2 and TIM P-2 in GCF were performd by ELISA.Results:Levels of MMP-2 and TIMP-2 were higher in patients than that in the controls(P

Objective To observe the histomorphological changes of sciatic nerves following pasteurizing warm temperature treatment. Methods The 12 mm left sciatic nerve from healthy adult male Wistar rats was pasteurized at 60℃ for 30 minutes and observed at the first week (1-week group) and the sixth week (6-week group), 15 rats per group. Number, diameter and area ratio of the myelinated axons in the control (proximal to the treated part), treatment and peripheral nerves (distal to the treated part) were calculated. The histomorphological changes were examined with electrophysiological and electron microscopies. Results (1) In the peripheral part, the number of the myelinated axons was significantly decreased in the 1-week group compared with the control group (P

Objective To evaluate the effects of nimodipine (NIM) on pregnancy induced hypertension(PIH) and to assesse the effects of nimodipine on intraplatelet free calcium(PF[Ca 2+ ] i). Methods Fourty eight patients with moderate or severe PIH were randomized to receive either NIM or magnesium sulfate. We observed the change of blood pressure, urc protein, PF[Ca 2+ ] i and symptoms of preeclampsia before and after medication. We compared the pregnancy outcome of the two groups. Results 1.There was significant reduction of blood pressure at 1/2 h?1 h and 2 h after the administration of nimodipine. The maternal heart rate increased significantly ( P

Objective To evaluate the clinical effects of Qufeng Jiedu Huoluo Decoction in treating the acute stage of periph-eral facial paralysis.Methods 60 cases of acute stage of peripheral facial paralysis were randomly divided into 2 groups,30 cases in each group.The two groups were treated by acupuncture.In addition the treatment group was added with oral Qufeng Jiedu Huoluo Decoction.Results The relief time of posterior auricular pain in the treatment group was shorter than that in the control group (P <0.05);the alleviation situation of the accompanying symptoms after 7 d and the neural function recovery situation after 14 d in the treatment group were superior to those in the control group (P < 0.05);the total effective rate in the treatment group was 93.3%,which was higher than 83.4% in the control group,the difference had statistical significance(P < 0.05).Conclusion Qufeng Jiedu Huoluo Decoction can effectively alleviate the clinical symptoms and signs of acute stage in peripheral facial paralysis.

Objective To investigate psychologically healthy condition of traumatic inpatients in orthopedics and analyze its in-fluence factors .Methods Cross-sectional study was conducted in Xi′an city .The mental health questionnaires for traumatic patients which include the Symptom Check List-90(SCL-90)and the related items were used .Results The results showed that 82 .7% of patients suffered from mild and moderate mental discomfort .The positive rate of mental problem was 14 .7% .The main mental rep-resentations of traumatic inpatients were depression ,hostility ,interpersonal relationship senstivity ,anxiety and somatization .The re-sults of single factor analysis showed that the bad mental health had the following characteristics :female ,low educational level ,little knowledge about disease ,bad interpersonal relationship ,introverted character ,cost ,dissatisfied with hospital ,severe disease and bad treatment .Logistic regression analysis revealed that the interpersonal relationship ,the degree of disease and gender were the main factors influencing patients′mental health .Conclusion The mental problem exists among traumatic inpatients in orthopedics .The degree of disease ,the interpersonal relationship and gender are the main factors affecting their mental health .

Aristolochic Acids ; adverse effects ; Humans ; Kidney Diseases ; chemically induced