OBJECTIVE To investigate the effect of different respiratory mask pressure on the upper airway volume(UAV),and to compare the changes of UAV between patients with obstructive sleep apnea hypopnea syndrome(OSAHS)and normal adults. METHODS Thirty three patients with OSAHS and thirty normal adults were included in this study.CT scan evaluated the UAV from roof of nasopharynx to glottis.UAV under different respiratory mask pressure between patients with OSAHS and normal adults were compared.RESULTS Patients with OSAHS had less UAV,and changes of UAV per cmH_2O were significantly smaller in patients with OSAHS than normal adults.CONCLUSION The results suggest that the quantitative data of UAV and changes of UAV per cmH_2O can be obtained.Upper airway anatomic narrowing and reduced airway distensible degree are major etiological factors for OSAHS.

This paper aims to elucidate the great impact of Latin, one of the most ancient languages, on the formation and development of English for Medical Purpose(EMP)from the historical point of view, and meanwhile provides it with detailed evidence in phonetic, lexical and grammatical respects.

Objective To investigate the relationship between serum uric acid(SUA)and clinic characteristics and result of coronary artery angiography of patients with coronary heart disease(CHD).Methods Two hundreds and seven patients for coronary artery angiography were divided into CHD group and control group.Their clinical data and results of coronary artery angiography were analyzed through statistics.Results SUA levels of CHD patients were significantly higher than the control subjects SUA(P

Executive function is an important advanced cognitive process, and it is the function that integrates different cognitive processes to achieve one's aim. Updating is an important component of executive function. According to the classifications of Miyake & Colletee on executive function, two study paradigms on memory updating are discussed: n-back paradigm & running memory paradigm. A new study method called latent variable analysis and new studies of cognitive neuroscience on memory updating are introduced. Issues on ethics and morality in research on cognitive experiment of psychology are briefly demonstrated to explore appropriate direction for research of executive function in future.

BACKGROUND: Cirrhosis can cause severe effect on spinal cord or other tissue and organ sometimes.OBJECTIVE: To establish cirrhosis model with rat liver injured by tetrachloride so as to investigate the distribution of nitric oxide synthase (NOS)in spinal cord of rats with cirrhosis.DESIGN: Completely randomized controlled study.SETTING: Anatomy Department of Capital University of Medical Sciences.MATERIALS: The experiment was completed at the Anatomy Department of Capital University of Medical Sciences from March 2002 to December 2003. Totally 20 male Wistar rats were divided randomly into cirrhosis group and normal group with 10 in each group.METHODS: Cirrhosis model in cirrhosis group was established with rat liver injured by tetrachloride, but rats in normal group were not treated with any method. After 3 months, total rats in the two groups were perfused and fixed; meanwhile, tissue of spinal cord was taken out for section.Quantity and gray degree of NOS positive cell in spinal cord of rats with cirrhosis were measured with nicotinamide adenine dinucleotide hydrogen phosphate-diaphorase (NADHP-d) histochemical method and Leica Q500IW image analysis system.MAIN OUTCOME MEASURES: [1] Gray degree of NOS positive neurons of rats in the two groups; [2] Distribution of NOS positive cell of rats in the two groups.RESULTS: Twenty rats all entered the final analysis. [1] Gray degree of NOS positive neurons of rats in the two groups was 60 (P ＞ 0.05). [2] In the area of gray matter of spinal cord, NOS positive cells were mainly distributed over the circumference of central canal, i.e. the Ⅹ layer of spinal cord and intermediolateral nucleus. Color of NADHP-d was positive, and the cellular form was shaped in triangle and fusiform. Cellular nucleus was not colored but color of cytoplasm was deep. The size of cells was moderate mainly of 25 μm. NOS positive cells were generally distributed averagely over intermediate zone of gray matter in cervical, thoracic and lumbar spinal cord and had no specific changes.CONCLUSION: Expression of NOS in spinal cord of rats in the cirrhosis group and the normal group is probably identical. Distributive characteristics of nitrogen monoxide (NO) in spinal cord suggest that adjustment on low sympathetic nerve of rats with cirrhosis is not different from that of the normal.

Through literature retrieval, the effects of transcutaneous electrical acupoint stimulation (TEAS) in peri-anesthesia period are summarized. It is found out that TEAS can reduce anesthetics consumption, relieve stress reaction of surgery, stabilize patients' hemodynamics, reduce surgical complication and improve immune function and quality of recovery; besides, it has protective function on heart, brain, liver, stomach, intestines and so on. However, except certain analgesic effect, the sham TEAS and transcutaneous electrial nerve stimulation do not have other functions of TEAS. The acupoint selection and stimulation parameter of TEAS in assisting anesthesia are still needed be improved and united.
Acupuncture Points ; Anesthesia ; Electric Stimulation ; Hemodynamics ; Humans ; Transcutaneous Electric Nerve Stimulation

Objective To explore the mechanisms on the damage in fetus liver,kidney and brain with administration of mifepristone and mesoproseol.Methods 17 specimens were obtained from the women who volunteered to terminate their pregnancy during 10～28 weeks.According to the fetus weight,they were divided into 3 groups.Immunohistochemistery was induced to investigate the expressions of pur-?,HSP70.Results The expressions of pur-? and HSP70 could be observed in both the treatment group and the control group.pur-? and HSP70 are the targets in detecting the damage of DNA.But pur-? was more sensitive than HSP70.The damage on group Ⅱ is the strongest.Conclusion Mifepristone can lead to the damage to lover,kidney and brain in mid-pregnancy.Its damage will be reducing as the growing of fetus.

Eligible 112 children aged 4-12 years old were recruited and assigned to 2 groups with block random design.For the first treatment session,the subjects in group 1 received computer-controlled anaesthesia(CCA) with autiovisual distraction of video-eyewear system(ADVS) intervention based on the routine therapy,those group 2 received only CCA and routine therapy.For the second session,a crossover of intervention methods were conducted for the 2 groups.Before and after each session,pain intensity and dental anxiety of each group were evaluated.Results showed that the group receiving CCA-ADVS presented significantly lower pain intensity and dental anxiety than the group receiving CCA only(P＜0.05).Evident differences were detected in the assessment outcomes in each treatment session (P＜0.0001).The combination of CCA and ADVS can effectively reduce pain perception and dental anxiety of children in pediatric endodontic treatment.

OBJECTIVE:To explore the clinical efficacy and safety of Leukotriene receptor antagonist combined with Gluco-corticoid nasal spray(called“intranasal steroid”for short)in the treatment of different degree of adenoidal hypertrophy(AH)com-plicated with allergic rhinitis (AR). METHODS:240 AR children with AH were randomly divided into control group,intranasal steroid group and drug combination group,with 80 cases in each group. Control group was given physiological seawater,3 presses each nostrile,in the morning and evening. The intranasal steroid group received Momestasone furoate nasal spray,one press each nostrile,qd. Drug combination group was additionally given leukotriene receptor antagonist Montelukast sodium chewable tablet,4 mg for under 5 year-old and 5 mg for 5-year-old or above,qd,at bedtime. Treatment course of 3 groups lasted for 12 weeks. The change of clinical symptoms and signs(such as nasal obstruction,snore,mouth breathing,etc)and adenoid/pharyngeal ratio(A/N ratio)were compared among 3 groups after treatment as well as the occurrence of ADR. Each group was divided into two sub-groups (medium and severe) according to the severity of AH so as to evaluate therapeutic efficacy. RESULTS:21 children withdrew from the study,including 11 cases in control group,6 in intranasal steroid group and 4 in drug combination group. After treatment,clinical symptom score and A/N in subgroups of drug combination group and intranasal steroid group were all lower than those of control group,with statistical significance(P<0.05). There was no statistical significance in clinical symptom score and A/N between drug combination group and AR complicated with medium AH subgroup from intranasal steroid group(P>0.05). Clini-cal symptom score and A/N of AR complicated with severe AH subgroup from drug combination group were lower than intranasal steroid group,with statistical significance (P<0.05). No obvious ADR occurred in 3 groups. CONCLUSIONS:Intranasal steroid alone and intranasal steroid combined with leukotriene receptor antagonist can improve clinical symptom of AR patients with AH, and reduce adenoid volume. It is suggested to use intranasal steroid firstly for medium AH complicated with AR,and additionally use Leukotriene receptor antagonist for severe AH complicated with AR.

Objective To evaluate the use of LHRH A for treating prostatic cancer with the occurrence of metastasis or recurrence after castration. Methods LHRH A has been instituted to 9 cases of pathologically verified prostatic cancer with the occurrence of metastasis or recurrence after castration.The therapeutic results were studied. Results Ideal improvement was noted in 4 with all the parameters turned normal.These 4 patients have survived well for 7,3,2 and 1 year respectively.Marked improvement occurred in 2 with part of the parameters turned normal or markedly improved shortly after the treatment.The condition of 1 patient became stable with drop of blood PSA and shrinkage of the prostatic mass.In 3 patients,the metastatic lesion became stable.with the use of LHRH A,the penis became markedly atrophic. Conclusions LHRH A is markedly effective in most cases of prostatic cancer with the occurrence of metastasis or recurrence after castration.The therapeutic efficacy depends on the sensitivity of the prostate cancer cells to the drug.Drug resistance may issue as time goes by.