Objective A pronunciation aid device had been made by using dental prosthodontic method for the treatment of pronunciation disorder, which is caused by movement dysfunction because of defect of soft palate tissues in cleft lip and palate patients.Methods According to the defect condition in the mouth, two types of pronunciation aid devices had been produced regularly by using maxillary impression, plaster casting and thermoplastic resin materials and so on. Results In the first group of cases, after 3 patients were wearing soft palate movement pronunciation aid device, and then they were given pronunciation training, it is found that their language clearances degrees had been promoted obviously. In the second group of cases, 2 patients were wearing naso-pharynx cavity closing pronunciation aid device, it is found that their nasal sound and nasal leakage were disappeared. And in the same time we gave patients pronunciation training, and after one year, their language clearances degrees were found to be more obviously increased than before.Conclusions Naso-pharynx cavity closing pronunciation aid device and soft palate movement pronunciation aid device are an effective non-surgical treatment methods for the treatment of naso-pharynx cavity closing dysfunction and soft palate movement dysfunction.

Objective To observe the different efficacy of combination of inhaled ipratropium bromide and salbutamol and inhaling the two drugs separately. Methods Sixty -five patients with COPD were divided into 3 groups,and treated with different drugs. We observed the lung function FEV1 , the improvement of symptoms and side - effects. Results The FEV_1 and improvement of symptoms in combination group were significantly better than those in seperatin group (P

This paper reviewed the thoracolumbar pedicle screw internal fixation,including operation,instruments,image guided navigation,robot navigation,electrophysiological monitoring and integrated applications of various methods.It suggested that traditional implantation of thoracolumbar pedicle screw were widely used,computer-assisted navigation is being accepted by more and more surgeons,MR can make special image of the tissue being drilled by the probe tip during operation.However,being expensive,it is difficult for MRI navigation to be popularized.

This paper analyzes social background and ethical problems of disposing and using unreasonably High-tech equipment, and puts forward relative proposals of contermeasure.

Objective To investigate the relationship between the pedicle and the transverse process in the thoracic and lumbar verte-brae. Methods 111antertior-posterior images of the lumbar vertebra and 111antertior-posterior images of the thoracic vertebra were chosen and lines were drawn between two pedicle centers of the same segment. The transverse process was divided into 4 equal parts by horizontal lines. The corresponding study was performed on the relationship between the pedicle and the transverse pro cess. Results Most of the T1～T2 pedicles corresponded to the midline of the transverse process. A large number of the T3～T11 pedicles corresponded to the upper 1/3 of the transverse process and the others corresponded to the upper margin, upper 1/4 or the midline of the transverse process. Most of the T12 pedicles corresponded to the upper margin of the transverse process. A large number of the L1, L2 and L5 pedicles corresponded to the upper 1/3 of the transverse process. A large number of the L3 and L4 pedicles corresponded to the midline of the transverse process. Conclusion The thoracic and lumbar pedicles have a multiform corresponding relationship with the transverse process.

Objective To explore the effect of active resistance exercise therapy on patients with chronic neck pain. Methods 39 femalepatients with neck pain more than 6 months were recruited in treatment group and received active resistance exercise therapy. 21 healthywomen were recruited in control group without any treatment. They were assessed with cervical curve (C2-7 Cobb's angle), CT attenuationvalue of cervical back muscle, neck muscular strength and endurance and visual analog scale (VAS) before and 12 months after treatment.Results Compared with the control group, the cervical curve of the treatment group was obviously less (P<0.05) and there was no significantdifference pre- and post-treatment P>0.05). The CT attenuation value of cervical back muscle was obviously less in the elder controlsthan in the middle aged ones (P<0.05); and was obviously less in the treatment group than in the controls (P<0.05), and not improved aftertreatment (P>0.05). Compared with the control group, neck muscular strength and endurance of the treatment group were obviously less (P<0.05), and improved after treatment (P<0.05). The score of VAS lowered 1 and 12 months after treatment (P<0.05). Conclusion Active resistanceexercise therapy can obviously improve neck muscular strength and endurance and relieve neck pain.

Lectin like oxidized low density lipoprotein receptor 1(LOX 1) is a type Ⅱ membrane protein belonging to the C type lectin family molecules which can act as a cell surface endocytosis receptor for oxidized LDL.LOX 1 can support binding, internalization and proteolytic degradation of oxidized LDL. And LOX 1 is involved in the platelet endothelium interaction and mediates phagocytosis of aged/apoptotic cells in endothelial cells ox LDL. Purification of soluble LOX 1 and the N terminal amino acid sequencing identified the two cleavage sites (Arg 86 Ser 87 and Lys 89 Ser 90 ). LOX 1 expression is not constitutive, but can be induced by proinflammatory stimuli, such as Angiotension Ⅱ, fluid shear stress and so on.

China ; Female ; Humans ; Neonatology ; ethics ; trends

Objective To evaluate the clinical efficacy of neo-adjuvant chemotherapy in the treatment of cervical cancer. Methods A total of 32 patients,of which 12 cases of Ⅰ b2,8 cases of Ⅱ a,5 case of Ⅱ b and 7 cases of Ⅲ, were all treated with 2 - 3 cycles of PF chemotherapy before treatment with cisplatin 100 mg/m2, d 1;5-fluorouracil 1000 mg/m2 ,d1-5. The chemotherapy was performed for 3 weeks followed by three weeks rest as one cycle. Results Short-term effect was 81.3% (26/32), with 3 cases of Ⅰ b2 and 1 cases of Ⅱ a had been completely relieved after 2 - 3 cycles of chemotherapies. Simultaneously, chemotherapy improved the removal rate of surgery. Among these 32 patients, there were 4 cases achieved complete response (CR) ,22 cases achieved partial response (PR) ,5 case of stable disease ( SD), 1 cases of progressive disease(PD). The overall response rate( CR +PR) was 81.3% (26/32) ,and the control rate ( CR + PR + SD) was 96. 9% (31/32). The main adverse events included myelosuppression and gastrointestinal response, which were all tolerable. Conclusions The neo-adjuvant chemotherapy reduced the size of cancer,which can improve removal rate of surgery and the quality of life.

The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.