OBJECTIVE:To observe clinical efficacy and safety of Autoserum eye drops in the treatment of filamentary kerati-tis after excimer laser corneal refractive surgery. METHODS:46 patients (90 eyes) with filamentary keratitis after excimer laser corneal refractive surgery were selected and randomly divided into control group and observation group with 23 cases(45 eyes)in each group. The control group was given clearing mesh+wearing soft contact lens+bFGF eye drops;the observation group was giv-en clearing mesh+ wearing soft contact lens + Autoserum eye drops. The clinical efficacy,cure time,recurrence rate and ADR were compared between 2 groups. RESULTS:The total effective rate of observation group was 93.3%,which was higher than that (82.2%)of the control group,with statistical significance(P<0.05);the cure time of observation group was(2.7±1.1)d,which was shortened significantly compared with control group [(3.5±1.2)d],with statistical significance(P<0.05). The recurrence rate of filamentous keratitis was 4.4% in observation group and 15.6% in control group;the observation group was significantly lower than the control group,with statistical significance(P<0.05). During the treatment,there were 1 case(1 eyes)of corneal epitheli-al edema in observation group and 2 cases (2 eyes) of corneal epithelial edema in control group,there was no statistical signifi-cance(P>0.05). CONCLUSIONS:In the treatment of filamentous keratitis after excimer laser corneal refractive surgery,therapy of clearing mesh+wearing soft contact lens+Autoserum eye drops have high total effective rate,low recurrence rate and short cure period with less ADR.

The test procedure and content of valves pressure test of AK95 hemodialysis machine are mainly introduced.The valves pressure test are the key of the self test procedure in hemsdialysis machine.It is necessary to find the accurate process where problems occur.[Chinese Medical Equipment Journal,2008,29(2):94]

The BM self-test of GAMBRO AK95 hemodialysis machine is introduced, including venous pressure test, arterial pressure test, priming detector test, blood pump test, venous clamp test, arterial clamp test, air detector test, high venous pressure test, etc. The detail introduction of high venous pressure test is of great benefit to solve some faults of hemodialysis machine.

BACKGROUND: Periprosthetic infection after total hip replacement usually results in surgery failure and needs a second operation.OBJECTIVE: To explore the pathogenesis, diagnosis and treatment of periprosthetic infection after total hip replacement by-reviewing and summarizing articles published in recent years.METHODS: A computed-based online search of Pubmed database was performed by using the key words of total hip arthroplasty, infection for manuscripts published from January 1990 to December 2010 and of those in SpringerLink database between January 1,1970 and December 31, 2010. A total of 2 109 manuscripts were retrieved. Moreover, related book or manuscripts that published by high-impact journals were included. Totally, 29 manuscripts were included. RESULTS AND CONCLUSION: The formation of biofilms on the surface of prosthesis is the main cause for hardly eradicated. Resistant bacteria and polymicrobial infection seems to be an increasing tendency. A correct diagnosis as soon as possible is very important to prognosis. However, without a gold-standard way, each mean has advantages and shortages, and comprehensive considerations are necessary. lnterleukin-6 seems a good choice for its inexpensive, non-invasive and a high sensitivity and specificity, which has aroused increasing attention. The antibiotics only, debridement with retention, one-stage replacement, two-stage replacement, joint arthrodesis, even amputation, are used to treat infection after total hip replacement. Prophylactic antibiotics are important to prevent infection. Antibiotic-loaded acrylic cement seems to be reliable and accept for more and more patients. However, each option must be selected according to the presence of infection individually.

Objective To observe the effect of triplex surgical treatment, including rectal mucosa ligation,Xiaozhiling injection,encircing fighting surgery of the anus ring,on complete rectum prolapse. Methods From February 2007 to February 2010,fifteen cases with complete rectum prolapse were enrolled into this study and accepted triplex surgical treatment All patients were followed up for 1-4 years. Results The curative rate of the triplex surgical treatment was 100% with no serious complications. Conclusion Triplex surgical treatment was a simple, effective and reliable method in treating complete rectum prolapse, with less pain,fewer complications and quicker recovery.

Unilateral neglect is one of the common advanced neurological deficits of stroke. This article highlights the post-stroke definition of unilateral neglect, incidence, sites of lesion resulting in neglect, possible mechanisms and clinical manifestation. It overviews the typing and complications of unilateral neglect, and points out that the significance on the assessment and treatment of unilateral neglect.

Objective To study the sedation efficacy of propofol combined with midazolam and /or fentanyl in fibreoptic choledochoscope. Methods Ninty outpatients were randomly divided into three groups. Group PF (n=31)was given fentanyl 0. 05 m.g plus propofol 1 mg/kg intravenously, group PM (n=29) midazolam 2 mg plus propofol 1 mg/kg, and group PMF(n=30) fentanyl 0. 05 mg, midazolam 2 mg and propofol 1 mg/kg. Propofol 20 mg was used when needed. HR,MAP,SpO_2,sedation scores and amnesia were recorded. Results All patients were awakened in 20 minutes after procedures. The recovery time was shorter in group PF than that in the other two groups. There were 21(67. 70%) patients in group PF, who were aware of surgery. Fifteen(48. 4%) patients were satisfied in group PF. Conclusion Propofol combined with midazolam and /or fentanyl in fibreoptic choledochoscope has better sedation without any obvious side effects.

Cough ; etiology ; therapy ; Humans ; Practice Guidelines as Topic

Objective To compare and analyze differences in clinical characteristics, auxiliary examination and im?munotherapy between children with anti-N-methyl-D-aspartate(NMDA) receptor encephalitis and adults. Methods Clinical data was retrospectively collected from 34 cases anti-NMDA receptor encephalitis. All people were divided into the child group and the adult according to the age of onset and the inpatient department. Score of Modified Rankin Scale (mRS) before and after treatment and follow-up period (6 months~24 months) were compared to estimate the neurologi?cal outcomes. Results Data from 34 patients including 19 children and 15 adults was analyzed. Hypoventilation, epilep?sy and status epilepticus were more common in the adult group than in the child. The positive rate of EEG delta brush was higher in child group than in adult group. Two women were complicated by suspicious ovarian teratoma. Intravenous immune globulin was used commonly in the child group, while the plasma exchange or immunosuppressant used common?ly in the adult group. Time of onset to hospital admission and final diagnosis were shorter in the child group than in the adult. Patients requiring ICU were fewer in the child group than in the adult. The scores of mRS were significantly lower in the child group than in the adult at hospital discharge (P<0.05). Conclusion Clinical characteristics is more compli?cated in adults with anti-NMDA receptor encephalitis compared with children including a worse disease severity and a poorer short-term outcome.

Objective To investigate the relationship between Sfrp5 and T2DM macroangiopathy , and to evaluate the activation of calcium dobesilate. Methods T2DM patients were divided into experimental group (IMT≥0.90 mm,n = 65)and control group (IMT < 0.90 mm, n = 30)and patients in experimental group were randomly further divided into group A (n = 30,treated with calcium dobesilate) and group B (n = 35, treated with routine therapy). Another 20 healthy control were involved as normal group. Sfrp5,IL-10,TC,TG,FPG, HbA1c and IMT were observed before and after treatment. Results Sfrp5 and IL-10 in experimental group and control group were lower than those in normal group (P < 0.01)and Sfrp5 and IL-10 in experimental group were lower than those in control group (P < 0.05). Correlation analysis showed that sfrp5 and IL-10 were negatively correlated with these above-mentioned indicators and Sfrp5 was positively correlated with IL-10(P < 0.05). After 16-week treatment, the contents of FBG, lipid, HbA1c and IMT were decreased in group A and B, but Sfrp5 and IL-10 were increased in group A (P < 0.01). Sfrp5 and IL-10 didn't alter significantly in group B (P >0.05). IMT in group A were decreased when compared with group B (P < 0.05). Conclusion Sfrp5 is negatively correlated with macroangiopathy. Calcium dobesilate can elevate Sfrp5 and IL-10,thus delay the progression of macroangiopathy.