Late preterm is labeled near term. As developmental immaturity, there was higher morbidity in late preterm infants compared with term infants. Especially brain injury, a 3-fold increased risk of cerebralpalsy and significantly higher rates of developmental delay and mental retardation for late preterm infants compared with term infants. In addition, a higher rates of neonatal complications had been documented on late preterm infants. These problems included apnea, hypoglycemia, hyperbilirubinemia, respiratory distress syndome, and poor feeding. It was known that long-term impact of these diseases will result in brain injury.

Objective To investigate the effect of sanbai granules on the patients with leucoderma.Methods 180 cases with leucoderma were selected and divided into two groups.90 cases in the control group were treated by Methoxsalen Tablets 10mg,1 times a day,2h sunlight after the medication,appropriate amount external of Compound Kaliziran tincture and Halometasone.90 cases in the experiment group were treated on the base of the control group with Sanbai granules.The activity of tyrosinase,amount of melanin in the serum,clinical effect and amount of skin regeneration between two groups were compared.Results Compared with the control group, the activity of tyrosinase and melanin in serum of the experiment group were higher (P<0.05),the clinical effect rate were higher(P<0.05),number of skin regeneration piece was higher(P<0.05).Conclusion Sanbai granules can effectively improve the activity of tyrosinase and melanin in patients with leucoderma, and it has important significance for the treatment of leucoderma.

Vitamin D ( VD) has been stated clearly in maintaining the balance of serumcalcium and phosphorus in human . Whereas, more and more evidences show VD has a considerable range of other physiological functions .VD has also been proposed to have vital functions controversially including adjusting immunity, antitumor, enhancing barrier in the intestine .The patients of short bowel syndrome are at particularly high risk of vitamin D deficiency .It has a significance in prevention and treatment of diseases to fur-ther clearly clarify the relationship and mechanisms of VD and the diseases .

Pancreatic cancer has a very poor prognosis, with a five-year survival less than 5%. Nowadays, to improve the treat-ment efficacy of pancreatic cancer has been a highlight for medical researchers worldwide. Increasing knowledge about the molecular pathogenesis of the disease has shown that genic mutations, such as oncogene Kras2, and anti-oncogenes Cdkn2a, and TP53, are hall-marks of pancreatic cancer. Therefore, it is vital to deeply understand the pathogenetic mechanism of pancreatic cancer and find new therapeutic strategies to cover it. In this review, we summarized the recent advances in the signaling pathways of pancreatic cancer.

Objective To study the risk factors and clinical features on acute hepatic dysfunction induced by sepsis.Methods One hundred and sixty-eight patients with sepsis were divided into 2 groups according to liver function:simple sepsis group (control group,142 cases) and acute hepatic dysfunction induced by sepsis group (observation group,26 cases).The biochemical indicators,plasma endothelin (ET)-1,sepsis-related organ failure assessment (SOFA) were compared between 2 groups.The risk factors of inducing acute hepatic dysfunction were analyzed.Results The incidence of acute hepatic dysfunction in 168 patients with sepsis was 15.5％ (26/168).The total bilirubin,direct bilirubin,creatinine,range of blood glucose variation,arterial blood lactic acid,plasma ET-1,SOFA,fatality rate in observation group were significantly higher than those in control group [(35.9 ±9.8) μμmol/L vs.(27.8 ±6.7) μmol/L,(17.7 ± 8.0) μ mol/L vs.(12.3 ± 5.9) μ mol/L,(219.6 ± 156.4) μ mol/L vs.(159.4 ± 125.3) μ mol/L,(7.6 ±4.9) mmol/L vs.(3.0 ± 1.6) mmol/L,(3.8 ± 1.3) mmol/L vs.(2.0 ± 1.2) mmol/L,(79.6 ±25.7)μg/L vs.(60.8 ± 12.6) μg/L,(8.8 ±2.6) scores vs.(5.7 ± 1.8) scores,38.5％ (10/26) vs.17.6％(25/142)],there were statistical differences (P ＜ 0.01 or ＜ 0.05).Multifactor Logistic regression analysis results showed that long-term drinking,cardiac insufficiency and hypotension were independent risk factors of acute hepatic dysfunction induced by sepsis.Conclusions The arterial blood lactic acid,plasma ET-1 and SOFA in patients with acute hepatic dysfunction induced by sepsis are higher.Long-term drinking,cardiac insufficiency and hypotension are the risk factors of acute hepatic dysfunction induced by sepsis.

Chinese herbs with bitter flavor have the function of purgation and dryness as well as strengthening yin.Strengthening Yin means keeping and maintaining yin fluid.Actually,it is to draw assistance from some Chinese herbs with bitter flavor to purge excessive fire in order to maintain yin qi by heat-clearing and fire-purging,that is to say purging fire to keep or save yin.Strengthening yin of bitter herbs is different from the moistening and nourishing function of sweet-cold herbs.It can be generally divided into three aspects: purging ministerial fire and restoring renal yin,clearing heat and purging fire to maintain yin fluid;purging to preserve yin.Strengthening yin doesn't mean the property and flavor of bitter-cold can nourish yin directly.We should not only emphasize clearing fire by using herbs with bitter in flavor and cold in nature,but also pay attention to nourish yin.It is causal relation that exists between purging fire and maintaining yin.The former is only a means and method,and the latter is objection and effect.Because the bitter-flavor can only damage yin by bitterness and dryness but is not good at benefiting yin,we cannot strengthen yin by using bitter herbs in treating yin-deficiency syndrome without excessive fire.

Bronchial asthma is defined as a chronic inflammatory airway disease in response to a wide variety of provoking stimuli.Over 200 million people in the world are affected with asthma.Because the incidence of asthma appears to be increasing,the importance of proper perioperative management of persons with asthma will also continue to increase.Patients with asthma are thought to be at high risk for pulmonary complications to develop during the perioperative period,and these complications may lead to serious morbidity.So it is very important to control asthma,to prevent and treat pulmonary complications for increasing operational success rate.

The implementation,operation and maintenance of building have huge impacts on environment and human health,however,the research about quantitative assessment of damage to human health for construction project still does not appear in China.Based on investigation in literatures about five LCA-based environmental impact assessment systems(EIA) systems,this paper concluded and compared the of health damage parts of the systems referred.Finally,some suggestions for establishing assessment systems of damage to human health especially in health damage indicators selection,characterization and weighting were proposed.

Nitrogen pollution in water body can not only cause eutrophication but also has direct hazardous effects on animals and human beings. The removal of ammonium is an important process in modern wastewater treatment systems. It is generally achieved by a traditional treatment system of combination of two processes,aerobic nitrification and anoxic denitrification,but these processes are very complex and the cost is higher. In recent years,some new principles have been proposed,such as aerobic denitrification,anaerobic ammonium oxidation,heterotrophic nitrification,which make simultaneous nitrification-denitrification possible. The domestic and foreign study progress in aerobic denitrification was reviewed in this paper.

Chemical constituents of the aerial parts of Qianhu were compared with those present in the roots by RP-HPLC. It was found that the constituents in aerial parts of Peucedanum praeruptorum are similar and higher in content than that in the roots. So it is possible that the aerial parts can be used instead of the roots of the plant. But the chemical constituents in the aerial parts and the roots of P. decursivum are quite different, rendering it impossible to use the aerial parts instead of the roots of the plant.