1.IIsolation and culture of enterochromaffin like cell and its functionaldetermination
Kun MIU ; Liang SUN ; Lh TANG ; ETAL ;
Chinese Journal of Digestion 1998;0(06):-
95 %viability .Histaminesecretionismeasuredbyenzymeimmunoassay .Basalsecretionwas (0 .6 ? 0 .2 )nmol/ 10 3cell.GastrinstimulatedhistaminesecretionwithEC50 of 3? 10 -10 mol/Landwasinhibited bypretreatmentofgastrinreceptorantagonistL3652 66,(IC50 10 -8mol/L) .TheDNAsynthesisofECLcell wasdeterminedbyBrdU .GastrinstimulatedECLcellDNAsynthesiswithEC50 of 2? 10 -11mol/L . ConclusionAboveresultsindicatedthatECLcellcouldlivewellinculturesystemandprovideagoodmeansfor investigatingcentralroleofECLcellfunction .
2.Empiric Meropenem-based versus Ceftazidime-based Therapy for Severe Community-Acquired Pneumonia in a Retrospective Cohort Study.
Nathalie Grace CHUA ; Yi Xin LIEW ; Winnie LEE ; Sarah S TANG ; Yvonne P ZHOU ; Karishma PATEL ; Andrea Lh KWA ; Maciej Piotr CHLEBICKI
Annals of the Academy of Medicine, Singapore 2019;48(3):98-103