1.Leptin and Bone Metabolism.
Journal of Korean Society of Endocrinology 2003;18(2):137-139
No abstract available.
Leptin*
;
Metabolism*
3.Leptin: It's Role in Food Intake and Body Weight Control.
Journal of Korean Society of Endocrinology 2000;15(6):722-735
No Abstract Available.
Body Weight*
;
Eating*
;
Leptin*
4.Obesity-Related Colorectal Cancer: The Role of Leptin.
Annals of Coloproctology 2015;31(6):209-210
No abstract available.
Colorectal Neoplasms*
;
Leptin*
5.Comments on "Improved Serum Leptin and Ghrelin Following Bariatric Surgery Predict better Postoperative Cognitive Function".
Mehmet AGILLI ; Fevzi Nuri AYDIN ; Yasemin GULCAN KURT ; Tuncer CAYCI
Journal of Clinical Neurology 2015;11(4):402-403
No abstract available.
Bariatric Surgery*
;
Ghrelin*
;
Leptin*
6.Role of Leptin in Puberty.
Journal of Korean Society of Pediatric Endocrinology 2000;5(1):18-22
No abstract available.
Adolescent
;
Humans
;
Leptin*
;
Puberty*
7.Research progress on the relationship between leptin and perimenopausal depression
Journal of Apoplexy and Nervous Diseases 2024;41(1):92-96
Perimenopausal period is a period with high incidence of female depression, which shows the symptoms of depressed mood and disturbed mind. The pathogenesis of the disease is not clear and it is urgent to search for efficient treatment. Leptin is a hormone secreted by fat cells and plays a role in both metabolism and neuroprotection. In recent years, leptin has been reported to ameliorate perimenopausal depression, and leptin is closely related to estrogen synthesis and secretion. Therefore, leptin may be used as a potential molecular target for the treatment of perimenopausal depression. In this paper, the research on the relationship between leptin and perimenopausal depression is reviewed.
Depression
;
Leptin
;
Estrogens
8.Leptin-signal transduction pathways and relationship with cancer development.
Korean Journal of Gynecologic Oncology 2007;18(2):67-92
Leptin is a versatile 16 kDa peptide hormone, with tertiary structure resembling that of members of the long-chain helical cytokine family. It is mainly produced by adipocytes in proportion to fat size stores, and was originally thought to act only as a satiety factor. However, the ubiquitous distribution of leptin receptors in almost all tissues underlies the pleiotropism of leptin. This review will focus on the link between leptin, a cytokine that is elevated in obese individuals, and cancer development through clarifying the intracellular signaling pathways of leptin. First, I discuss the biological functions of leptin and its signaling pathways. Then, I summarize the effects of leptin on different cancer types in experimental cellular and animal models. Next, I analyze the relationship between obesity and the presence of cancer or cancer risk in patients. Finally, leptin as a target for cancer treatment in the future and prevention will be discussed.
Adipocytes
;
Carcinogenesis
;
Humans
;
Leptin
;
Models, Animal
;
Obesity
;
Receptors, Leptin
9.Regulation of Leptin and Resistin Gene Expression:Roles in Food Intake and Glucose Metabolism.
Journal of Korean Society of Pediatric Endocrinology 2001;6(2):104-106
No abstract available.
Eating*
;
Glucose*
;
Leptin*
;
Metabolism*
;
Resistin*
10.Prevalence of Metabolic Syndrome in Rural Populace: A Study of Its Association With Adipocytokines
Hiroyuki OHBAYASHI ; Hirohiko YAMASE ; Shiro KAWASHIMA ; Koutarou HAYASHI ; Hiroyuki NOSAKA ; Takashi HIRAISHI
Journal of the Japanese Association of Rural Medicine 2006;55(5):449-458
The purpose of this study was to shed light on the prevalence of the metabolic syndrome (MetS) in a rural community and examine whether or not serum adipocytokine levels are associated with the Diagnostic Criteria for MetS and how many MetS components laid down in the standards subjects have. The subjects were 2,858 people (1,744men and 1,114 women, mean age 49.8+/-9.9 yrs) who had participated in our health screening program between April and December, 2005. After obtaining informed consent from them, we measured serum leptin, adiponectin and high-sensitivity C-reactive protein levels, while performing routine blood tests. In the present study, these measurements were used in combination with the number of MetS components applicable to the conditions of our subjects. Two hundred men (11.5%) and 25 women (2.2%) were diagnosed with MetS. The number of MetS women was extremely small. Those women who were above the standard waist circumference of above 90cm accounted for 8.7% of the total. Thus, most women subjects were excluded as MetS candidates here. The leptin levels of the MetS group were higher than those of the non-MetS group in accordance with the number of applicable components in the diagnostic standards for MetS. Especially, the MetS group which met three MetS criteria showed significantly high leptin levels (p/5=0.0081) of 5.26+/-1.86 (ng/ml) compared to 3.31+/-1.44 (ng/ml) of the non-MetS group with waist circumference below 85cm. On the other hand, no significant difference was noted between the groups in adiponectin level. However, in contrast to leptin levels, adiponectin levels were lower in the group having three MetS components than the non-MetS group 4.37+/-1.57 (ng/ml) as against 5.52+/-3.34 (ng/ml). High-sensitivity CRP levels did not show any significant difference between the two groups.As regards the cutoff value of women's waist circumference, further study needs to be done. It was suggested that serum leptin levels might be closely related to the diagnostic criteria for MetS and the number of MetS components applicable.
Human Females
;
Leptin
;
ng/mL
;
seconds
;
adiponectin