1.Revaluation of tumor response evaluation criteria in solid tumors
Journal of International Oncology 2008;35(5):343-346
Response Evaluation Criteria In Solid Tumors (RECIST) and WHO Criteria are the most in portant ones.There are some differences between them,in one word,RECIST is better than WHO Criteria when implemented in clinic.However,there are some shortcomings in RECIST.Improvement is needed to make the criteria more and more Derfect and scientific.
2.Evaluation of clinical efficacy of accommodating intraocular lens implantation in pseudophakic eyes from the perspective of morphological studies
Chinese Journal of Experimental Ophthalmology 2015;33(11):1037-1042
The accommodating intraocular lens (AIOL) is designed to simulate the accommodation of the crystalline lens and satisfy patients by its ability to focus on an object at any distance independent of spectacles.However,near vision in the short-term or long-term future of some patients with AIOLs is not good in clinical practice and there is still no consistent conclusion as to whether they can restore sufficient accommodation.Most clinical evaluations of AIOL performance have been based on visual function, such as the testing of near visual acuity and subjective measurements of accommodation,but these tests may not determine whether the lenses are actually working according to the principle of their design.With the rapid development of imaging technologies, the performance of AIOLs can be observed from the perspective of morphology.This article described the biometry of the anterior segments in the subjects with AIOL during accommodation in order to understand the actual clinical effects of AIOLs.
3.The associations of single nucleotide polymorphisms on bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein with the susceptibility of infection
Journal of Medical Postgraduates 2003;0(06):-
Objective: To investigate the associations of single nucleotide polymorphisms(SNP) on bactericidal/permeability-increasing protein(BPI) and lipopolysaccharide-binding protein(LBP) with the complication of sepsis. Methods: The SNP genotypes of BPI Lys216Glu,PstⅠin intron 5,G545C,LBP Cys98Gly and Leu436Pro were examined by restriction fragment length polymorphism PCR(PCR-RFLP).Results:The rate of BPI Lys216Glu G/G genotypes and G-alleles in patients with sepsis were significantly higher than that of volunteers.The rate of BPI Lys216Glu G/G genotypes and G-alleles in nonsurviving patients were significantly higher than that of survivor patients. Conclusion: The BPI Lys216Glu G-allele may be associated with the high risk of sepsis.
4.Expression and position fixing of bFGF in retina of diabetic rabbits
Journal of Jilin University(Medicine Edition) 2006;0(04):-
Objective To investigate the expression period of bFGF and the correlation between the M?ller cells in retina and the increasing of bFGF expression in diabetic rabbits.Methods Sixteen rabbits were divided randomly into normal control and diabetic groups.After the models of diabetic rabbits were set up,the rabbits were breeded for 7 weeks.The immunofluorescence double labeling method and laser confocal microscopy were used to observe the ratina of the diabetic rabbits and the position fixing of bFGF was studied.Results In normal control group,the structure of each layer of retina was clear,the cell lined up tightly and regularly with normal shape,the location with red fluorescence was M?ller cells signaled with GFAP,labeled with bFGF,only on capillary basement membrane the red fluorescence could be found.In diabetic group,the structure of each layer of retina was clear,the cells of INL and GCL lined up loosely,the intercellular space increased,there was no significant difference compared with normal group on cell shape.Labeled with bFGF,the different intensity red fluorescence could be found in each layer cells,double labeled with GFAP and bFGF,the yellow fluorescence could be found.The retinopathy of diabetic rabbit was in BDR stage.The expression of bFGF increased in this stage.The bFGF and GFAP coexpressed in M?ller cells.Conclusion The bFGF begins to express in the M?ller cells from the BDR stage.
5.The Present Status and Countermeasure of Clinically Monitoring Blood Drug Concentrations in Hospital Pharmacy in Shanxi Province
China Pharmacy 1991;0(04):-
This paper describes the present status and existing problems of clinically monitoring blood drug concentrations, in hospital pharmacy in Shanxi Province. The ways to solve these problems are suggested.
6.Clinical analysis of orbital tumors
Ophthalmology in China 1993;0(01):-
The series of 441 cases of orbital tumor comprised 245 males and 196 females whose age ranged from 6 months to 60 years.The tumors of high incidence in order of impor- tance were hemangioma,dermoid cyst,mu- cocele,meningioma,and optic neuroglioma. A modified surgical approach was mode for complete removal of tumors located in the poste,ronasal aspect of the orbit.Besides, other approaches to the orbital apex were also attempted in addition to regular routes.
8.Ultrasound Guidance of Central Vein Catheterization by External Jugular Vein Puncture
Weichun LENG ; Lijuan GUO ; Xin LENG ; Guijuan HE ; Yunpeng LENG
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To develop technique of central vein catheterization by external jugular vein puncture under ultrasound guidance.METHODS A total of 224 patients with central vein catheterization by external jugular vein puncture were randomized into two groups: the control group was treated by routine manipulation and observed blood vessels by macroscopic observation;the patients from the observation group were placed catheters with the assist of ultrasound techniques.To record the one time achievement ratio of catheterization and incidence of phlebitis and thrombus.RESULTS Comparing the two groups,we found the observation group had higher one time achievement ratio of catheterization and lower incidence of phlebitis and thrombus than that of the control group.And there were statistical significances between the two groups(P
9.Handwriting as an objective test of performance ability.
Singapore medical journal 1970;11(4):222-224
10.Medical ideology: a problem of survival.
Singapore medical journal 1970;11(4):206-207