1.Clinical study of treating systemic lupus erythematosus encephalopathy with different immuno-suppressants
Journal of Clinical Neurology 1995;0(04):-
Objective To investigate the efficacy and safety of three kinds of immunosuppressant on systemic lupus erythematosus encephalopathy. Methods 44 cases with systemic lupus erythematosus encephalopathy were randomly assigned to receive high dose of Methyllprednisolone, Cytoxan (CTX) or Ifosfamide (IFO). The levels of ESR and serum C_3 were detected at different time after treatments. The effect and safety of these treatments were evaluated. Results (1) After treatment, the levels of ESR decreased significantly ((P)0.05). More decrease of ESR was found in CTX group and IFO group than in Methyllprednisolone group (all (P
2.Exploration and Utilization on Potential Function ofRehmannia Glutinosa
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(5):1036-1041
This study was aimed to investigate the functions and indications ofRehmannia glutinosa from old herbalism documents. The database management system ofPu-Ji-Fang was used to summarize the whole function, which was compared with theChinese Pharmacopoeia 2010 edition. The results showed that besides the same function,R. glutinosa was also widely used in the treatment of various heat syndromes, deficiency, sore ulcer, traumatism, irregular menstruation, arthralgia, blood stasis, apoplexia, cough, restlessness, and etc. With modern studies on pharmacodynamics and clinical applications, potential functions ofR. glutinosa were primarily conformed as clearing heat-fire (clearing heat-toxin), tonifying, promoting blood circulation to remove blood stasis, soothing nerves, calming liver to extinguish wind, and removing wind-damp syndromes.
3.On Fundamental Features of TCM Psychological Theory of Sun Simiao
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(02):-
As an independent subject, TCM psychology appeared in 1980s, but it could be traced back to the book, the Inner Canon of Huangdi (Huangdineijing) formed in Qin and Han Dynasties. Physicians in the later generations developed TCM psychology based on that occurred in the Inner Canon of Huangdi, which made it became mature gradually, and Sun Simiao was one representative figure among them. The fundamental features of TCM psychological theory of Sun Simiao are summarized here.
4.Discussion on the Application of Crisis Public Relations Principles to Dealing with Medical Dissensions
Chinese Journal of Medical Education Research 2006;0(12):-
This paper aims to integrate the principles of crisis public relations into the hospitals'real facts of management,and make some discussion and analysis in dealing with medical dissensions,in expectation of throwing a brick to get a gem in return in order to enhance the hospitals'power of resisting risks and competion.
5.Correlation between dry eye and refractive regression after laser in situ keratomileusis
International Eye Science 2009;9(11):2054-2056
AIM:To investigate the correlation between chronic dry eye and refractive regression after laser in situ keratomileusis (LASIK)for myopia.METHODS:Two hundred and twenty-five eyes of 225 patients were enrolled in this study.Examinations including Schirmer test,tear break-up time(BUT),corneal sensation,and ocular surface staining were performed before and 6 months after LASIK.Dry eye symptoms were assessed using the McMonnies Dry Eye Symptom Survey.Data were analyzed on history and treatment response.RESULTS:Refractive regression after LASIK was related to chronic dry eye.It occurred in 8(25.0%)of 32 patients with chronic dry eye and in 18(9.3%)of 193 patients without dry eye(P<0.01).CONCLUSION:The risk of refractive regression was increased in patients with chronic dry eye.
6.Effect of different types of cements and the timing of tooth preparation on the coronal microleakage of fiber post
Huiyun LEI ; Lei CHEN ; Guofu XU ; Xiaopeng LIANG ; Jijia LI
Chinese Journal of Tissue Engineering Research 2010;14(3):461-464
BACKGROUND: The vibration of high speed handpiece during tooth preparation may have adverse effect on the continuous force of the bonding interfaces among the cement, dentin, and post core. OBJECTIVE: To find the effect of different types of cements on the coronal microleakage of fiber post under different tooth preparation timings, and to provide evidence for the clinical operation. METHODS: The extracted mandibular premolars were divided into 3 groups, and they were cemented by Rely X luting, Panavia F and Paracora 5 mL, respectively. Each group was averagely divided into 3 subgroups: A, B, C groups which were prepared 15 minutes, 45 minutes, and 90 minutes after the cements mixed. All roots were then dyed and transparented. The teeth were observed under stereoscopic microscope and the dyeing scores were also recorded. RESULTS AND CONCLUSION: Rely X luting caused the highest coronal microleakage of fiber post, followed by Panavia F, while Paracore 5 mL, brought about the lowest under the same tooth preparation timing. Different tooth preparation timing caused no significant effect on the coronal microleakage of fiber post when the cement had been completely set.
7.Rapid identification of chemical constituents in Salvia chinensis by HPLC-TOF-MS.
Yan-Ni ZHOU ; Liang ZHAO ; Lei ZHENG ; Lei LV
China Journal of Chinese Materia Medica 2013;38(23):4109-4112
It's established a high-performance liquid chromatography-time of flight mass spectrometry(HPLC-TOF-MS) method to analyze chemical constituents in Salvia chinensis. The separation was performed on a SHISEIDO MG C18 reverse phase column (3.0 mm x 100 mm, 3 microm). The mobile phase consisted of acetonitrile (A) and water (containing 0.1% formic acid, B) was used as gradient elute. The gradient of a phase, 10%-90% (0-33 min), 90% (33-40 min). The flow rate was 0.6 mL x min(-1). Post-column split ratio was 2:1. Temperature of column was 25 degrees C. Time-of-flight mass spectrometer (TOF-MS) and electrospray ion source (ESI) was applied for qualitative analysis under positive ion mode, and mass scan range was m/z 100-1 000. As a result,28 of the major chemical constituents of S. chinensis were identified by HPLC-TOF-MS. In this study, a rapid and efficient method for studying the chemical constituents in S. chinensis by HPLC-TOF-MS was established, which paves a way for the quality control and further studies of the herb in vivo.
Chromatography, High Pressure Liquid
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Mass Spectrometry
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Organic Chemicals
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analysis
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isolation & purification
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Salvia
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chemistry
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Solvents
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chemistry
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Time Factors
8.Clinical analysis of cellular schwannoma in the gastric wall misdiagnosed as gastric stromal tumor
Guangyao WANG ; Ping CHEN ; Lei WANG ; Liang ZONG ; Lei SHI
Chinese Journal of Digestive Surgery 2013;(4):315-316
Cellular schwannoma is a rare benign tumor of the peripheral nerves.The tumor is consist of spindle cells which arranged in interwoven bundles,and lacking the mesh district and palisading structure.The tumor cells are abundant,with coarse chromatin,deeply stained nuclei and in multiforms.So the tumor may easily be misdiagnosed as various types of spindle cell sarcoma.Intraperitoneal cellular schwannoma may also be mistaken as gastrointestinal stromal tumors.In this article,the clinical characteristics,diagnosis and treatment of cellular schwannoma were analyzed based on the clinical data of a patient with cellular schwannoma in the gastric wall misdiagnosed as gastric stromal tumor.
9.Study on the medical services monitoring under the concept of big data
Yan ZHANG ; Lei DUAN ; Liang ZHANG
Chinese Journal of Health Policy 2017;10(7):71-74
Medical service utilization monitoring of county areas residents is one of the important contents of health policy management and research.Traditional service utilization monitoring, such as National Health Services Survey (NHSS), residents healthcare treatment (clinical) data from medical insurance, had problems of high cost, large deviation, slowly updating monitoring indicators, out of time in health management decisions.The data convergence and re-architecture of multi-source data provide a new idea for the monitoring of residents'' service utilization.Different linking data-sources would come true with the tools of Microsoft Access database administration and Excel programming techniques.At the same time, a new database would be accessed with the indices of residents'' annual medical service utilization, preference in medical services, unconscionable service utilization, and lead to the promotion of medical service utilization monitoring research development.
10.Comparison of sevoflurane and propofol on cerebral oxygen metabolism and postoperative cognitive function during anesthesia maintenance
Shenghua CEN ; Haiqing FU ; Lei LIANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):177-179,182
Objective To compare of sevoflurane and propofol on cerebral oxygen metabolism and postoperative cognitive function during anesthesia maintenance.MethodsSeventy emergency trauma patients admitted to Zhoushan Hospital from August 2014 to August 2015, whom were randomLy divided into two groups (n=35 each): The control group anesthesia maintained by propofol;while the observation group were maintained with sevoflurane anesthesia.The changes of cerebral oxygen metabolism were compared between the two groups at different time points during anesthesia maintenance, and the Mini-Mental State Examination(MMSE) score, Trail-Making Test(TMT)completion time and the incidence of adverse reactions after recovery were also compared.ResultsThe SjvO2 values of each group were much higher in 2 min after induction (T2), 2 min after tracheal extubation (T3) than those before anesthesia (T1), while the Da-jvO2 and COER values were significantly decreased in T2 and T3 than those in T1, and the differences were statistically significant (P<0.05).These values were wihtout significant difference between the two groups in each period.The TMT completion time of the control group was prolonged than before induction, while the MMSE score was decreased than before induction, and the differences were statistically significant (P<0.05).There was no significant difference in TMT completion time and MMSE score in the observation group before and after induction.The incidence of adverse reactions between the two groups was not statistically significant.The eye opening time, orientation recovery time and anal exhaust time of control group were much later than those in observation group, and the differences were statistically significant (P<0.05).ConclusionSevoflurane and propofol can meet the need of maintaining the cerebral oxygen balance during anesthesia maintenance, but sevoflurane anesthesia has fewer influences in post-operation cognitive function.