1.Construct an Innovation-Oriented Campus Culture and Strengthen the Career Starting Concept among College Students
Chinese Medical Ethics 1995;0(03):-
Embodied as an abstract concept as well as concrete regulations and material environment on the campus,the campus culture is the organizational culture among universities,which plays a significant role in enhancing students' quality of career starting.Similar to its social culture,the American campus culture is characterized by a strong personal heroism thus is known as a "cowboy culture".As the so-called "dragon culture",the Chinese culture is a more conservative one and thus lack of innovation-oriented career starting concepts among Chinese university students.Therefore,in order to effectively carry out entrepreneurship education in colleges and universities,the innovation-oriented campus culture should be constructed,students' entrepreneurship conception strengthened,thus students' sense of career starting and mental status be enhanced.
2.Survey of the Application of Acupuncture and Moxibustion to the Non-spastic Stage of Cerebral Stroke
Shanghai Journal of Acupuncture and Moxibustion 2015;(11):1135-1138
This article consults the literature on acupuncture-moxibustion treatment for the non-spastic stage of cerebral stroke published from 2001 to 2014, makes a summary and analysis from meridians, point selection, acupuncture reinforcing-reducing techniques and electoacupuncture application and points out some problems such as valuing acupuncture and neglecting moxibustion, valuing acupuncture and neglecting medicine, and neglecting point selection based on syndrome differentiation in acupuncture-moxibustion treatment for the non-spastic stage of cerebral stroke. The article also objectively assesses the position of acupuncture-moxibustion treatment, puts forward relevant solving ideas and emphasizes the importance of acupuncture manipulation and the necessity for combining Chinese herbal medicine to treat the non-spastic stage of cerebral stroke.
3.The efficacy of tibial shaft fractures treated with interlocking nails
Chinese Journal of Postgraduates of Medicine 2014;37(8):37-40
Objective To investigate the difference of efficacy of interlocking nails and dynamic compression plate in tibial shaft fractures.Methods The clinical data of 137 cases with tibial shaft fractures were reviewed retrospectively.They were divided into two groups according to the various treatments which included interlocking nails group(72 cases with 79 fractures) and dynamic compression plate group(65 cases with 70 fractures).The efficacy,healing fineness rate,function score after operation and complications were compared.Results After operation,the patients were followed up 21.4 months on average.The postoperative callus time,weight-bearing limb time,healing time and postoperative fixation time taken in interlocking nails group was shorter than that in dynamic compression plate group [(2.36 ± 0.46) months vs.(3.12 ± 0.57) months,(2.42 ± 0.51) months vs.(3.14 ± 0.63) months,(7.65 ± 1.29) months vs.(9.33 ±1.54) months,(12.64 ± 3.76) months vs.(16.38 ± 3.15) months],and there was significant difference (P< 0.05).The healing fineness rate was 97.5%(77/79) in interlocking nails group,and 92.9%(65/70) in dynamic compression plate group,and there was nosignificant difference (x2 =1.76,P >0.05).The incidence of comphcations in interlocking nails group was higher than that in dynamic compression plate group[25%(2H9) vs.12.9%(9H0)],and there was significant difference(P < 0.05).Condmions Interlocking nails have better biomechanical features with high union rate,low infective rate and good recovery of joint function.The clinical result of interlocking nails for the tibial shaft fractures is also better than that of dynamic compression plate.
4.Endocrine therapy for postmenopausal women with hormone receptor positive in advanced breast cancer
Journal of International Oncology 2016;43(7):529-531
With the emergence of new endocrine drugs and the development of research in resistance mechanisms,significant progress has been achieved in the endocrine treatment of breast cancer in recent years. Fulvestrant,the combination of endocrine drugs and the combination of targeted therapy with endocrine therapy will be effective treatments for postmenopausal women with hormone receptor positive in advanced breast cancer.
5.Application of Incorporation Technology of ~3H-TdR in Study on Anti-cancer Preparations of Compound Chinese Medicines
Chinese Traditional Patent Medicine 1992;0(12):-
A rapid, sensitive, reliable and simple microdetermination technology for anti-cancer activity, incorporation technology of ~3H-TdR, was developed to seek the process for anti-cancer preparations of compound Chinese medicines. In such a way, more rational process could be drafted during the short time. The preparation made by this process was found to possess good curative effect, no obvious toxicity and no side-effect in the compreshensive evaluation of clinic and a total 14 biology indexes, The application of some rapid and sensitive medical-determination technology in studies of preparation process, quality standards and stability could solve some problems induced by indefinite active components, make research way broad, and raise research level.
6.Comparison of clustering methods in light of paper similarity network topology
Chinese Journal of Medical Library and Information Science 2015;24(10):33-38
A paper similarity network was constructed in light of semantic similarity algorithm using the complex network processing package , igraph in R language , and analyzed by random walk-trap algorithm , label propagation algorithm, BGII algorithm, and Girvan-Newman algorithm, respectively.The accuracy and stability of these 4 al-gorithms were compared according to the golden standards and the D function for network community classification evaluation index, which showed that the accuracy and stability of random walk-trap algorithm were better than those of the other 3 algorithms and preconditioning of complex network was an important influencing factor for clustering .
7.The importance in the experimental diagnosis value of exosome
Chinese Journal of Laboratory Medicine 2015;38(11):724-726
Exosome is nanoscale vesicles with bilayer membrane structure, is secreted by multiple living cells in vivo, capable of carrying biological materials such as nucleic acids, proteins and lipids etc.Exosome can protect the information material (such as miRNA), which is easy to be inactivated or degraded in the circulatory system, so that they can be safely transferred to the specific target cells to participate in signal regulation, and play an important role in the information transmission between cells.Exosome is widely found in human blood, urine, pleural effusion and other body fluid samples, and can provide rich, stable, sensitive and specific biological information.As a kind of liquid biopsy specimen, exosome has a very high clinical application value in the future.
8.Diagnosis and treatment of congenital/inherited renal tubular diseases in children
Chinese Journal of Applied Clinical Pediatrics 2015;30(17):1285-1289
Hereditary renal diseases (inherited kidney diseases) include glomerular diseases,tubular diseases and cystic diseases.The incidence of inherited kidney diseases is relatively low, but the variety of clinical insufficient understanding of the disease, the means test about inherited kidney diseases is also not standardized, easily lead to missed diagnosis and misdiagnosis.As the common clinical manifestation of hereditary renal disease and congenital/hereditary renal disease are mainly low blood potassium, kidney stones, polyuria, growth retardation, and may develop renal failure without treatment.Therefore, clinicians should pay special attention to the diagnosis of congenital/hereditary renal disease, and early interventions are recommended.
9.Mining the relation between leukemia and genes using Weka
Chinese Journal of Medical Library and Information Science 2015;(1):50-54,60
Objective To mine the relation between leukemia and genes using Weka. Methods The papers on leuke-mia and genes were retrieved from PubMed, their subject headings and subheadings were extracted using BICOMB to generate co-occurrence matrix and term-paper matrix. The research hotspots were found by cluster analysis of the data on co-occurrence matrix using Weka and Cobweb. The literature was verified. Results The 42 high fre-quency words were clustered into 7 classes by Weka. No high frequency words of leukemia or genes were found in classes 1, 2, 4 and 5, indicating that their clustering efficiency was poor. The clustering efficiency of the other 3 classes was good. Conclusion Cluster analysis showed that leukemia is related with myc gene, ab1 gene, p53 gene, virus gene, immunoglobulin gene and mdm gene.
10.Effect of Naoxintong capsule on clinical efficacy and inflammatory factors in patients with ischemic stroke
Chinese Journal of Primary Medicine and Pharmacy 2017;24(18):2792-2795
Objective To investigate the effect of Naoxintong capsule on clinical efficacy and inflammatory factors in patients with ischemic stroke.Methods 81 patients with ischemic stroke were divided into two groups according to random number table method.40 patients in the control group were treated with treatment guidelines,and the observation group was treated with another Naoxintong capsule.The serum interleukin-10(IL-10),tumor necrosis factor-a(TNF-α),high sensitivity C reactive protein (hs-CRP) level,National Institutes of Health Stroke Scale (NIHSS) and clinical efficacy of two groups were compared.Results After treatment,the hs-CRP,TNF-α levels of the observation group were (12.36 ± 3.09) mg/L,(129.62 ± 29.27) mg/L,which were lower than those of the control group[(1 6.71 ± 4.29) mg/L,(186.52 ± 37.62) ng/L,t =8.189,5.287,all P < 0.05).After treatment for 7d and 30d,the NIHSS scores of the observation group were (14.28 ± 3.24) points,(5.23 ± 1.47) points,which were lower than those of the control group[(18.76 ±4.53)points,(8.16 ±2.42)points,t =14.689,12.827,all P <0.05].IL-10 level of the observation group was (49.82 ± 6.59) pg/mL,which was higher than (42.57 ± 9.82) pg/mL of the control group (t =6.759,P < 0.05).The total effective rate of the observation group was 92.68%,which was higher than 77.50% of the control group (x2 =4.897,P < 0.05).Conclusion Naoxintong capsule has significant therapeutic effect on ischemic stroke,can effectively improve the inflammatory reaction after cerebral infarction,promote the recovery of neurological function and it is worthy of promotion.