1.Is there a Significant Difference in Surgery and Outcomes between Unipolar and Bipolar Hip Hemiarthroplasty? A Retrospective Study of a Single Institution in Singapore
Malaysian Orthopaedic Journal 2011;5(1):3-7
Objective: The aim was to compare outcomes differences between unipolar and bipolar hip hemiarthroplasty in one institution for the local geriatric population. Methodology: A retrospective review of 291 patients aged 70 and above who underwent hip hemiarthroplasty for neck of femur fracture from February 2004 to November 2006 was performed. Results: Operative time was lower in the unipolar group. There was no statistically significant difference between the groups in terms of superficial wound infection, d
2.Effect of extracts from Stachys sieboldii Miq. on cellular reactive oxygen species and glutathione production and genomic DNA oxidation
Asian Pacific Journal of Tropical Biomedicine 2018;8(10):485-489
Objective: To evaluate the antioxidant activity of extracts and fractions from Stachys sieboldii Miq., and to examine its effect on the cellular reactive oxygen species (ROS) and glutathione (GSH) production and genomic DNA oxidation in HT-1080 cells.Methods: The ROS generation induced by H2O2 was measured by the dichlorofluorescein-diacetate assay. GSH levels were measured using a fluorescent method with mBBr. Genomic DNA oxidative damage was measured with levels of oxidative DNA induced by the reaction of ferritin with H2O2.Results: Then-hexane, 85% aqueous methanol andn-butanol fractions (0.05 mg/mL concentrations) inhibited H2O2-induced ROS generation by 63%, 35% and 45%, respectively. GSH levels were significantly increased in both acetone+methylene chloride and methanol extracts (P<0.05). Supplementation of cells withn-hexane significantly increased GSH levels at concentrations of 0.05 mg/mL (P<0.05). Both the acetone+methylene chloride and methanol extracts, as well as all fractions significantly inhibited oxidative DNA damage (P<0.05). Conclusions: These results indicate that cellular oxidation was inhibited by then-hexane fraction and this fraction may contain valuable active compounds.
3.Peritoneal implantation of ureter in a cadaveric kidney transplant recipient.
Tan SY ; Lim CS ; Teo SM ; Lee SH ; Razack A ; Loh CS
The Medical Journal of Malaysia 2003;58(5):769-770
We report here a case of a kidney transplant recipient in whom the ureter was initially implanted into the peritoneum. Excessive ultrafiltration volume and reversal of serum vs dialysate creatinine ratio when the patient was recommenced on continuous ambulatory peritoneal dialysis first suggested the diagnosis which was subsequently confirmed by a plain abdominal x-ray demonstrating placement of ureteric stent in the peritoneum. This rare complication was successfully corrected with surgical re-implantation of ureter into the bladder and 5 years later, the patient remains well with good graft function.
Cadaver
;
Kidney Transplantation/*methods
;
Postoperative Complications
;
Reoperation
;
Replantation
;
Ureter/*surgery
4.Relapsing Course of Sulfasalazine-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Complicated by Alopecia Universalis and Vitiligo.
Bertrand Sy LIAN ; Inny BUSMANIS ; Haur Yueh LEE
Annals of the Academy of Medicine, Singapore 2018;47(11):492-493
Alopecia
;
chemically induced
;
diagnosis
;
Antirheumatic Agents
;
administration & dosage
;
adverse effects
;
Arthritis, Rheumatoid
;
drug therapy
;
Biopsy
;
methods
;
Cyclosporine
;
administration & dosage
;
Dermatologic Agents
;
administration & dosage
;
Drug Hypersensitivity Syndrome
;
diagnosis
;
etiology
;
physiopathology
;
therapy
;
Humans
;
Male
;
Middle Aged
;
Prednisolone
;
administration & dosage
;
Skin
;
pathology
;
Sulfasalazine
;
administration & dosage
;
adverse effects
;
Symptom Flare Up
;
Treatment Outcome
;
Vitiligo
;
chemically induced
;
diagnosis
5.Result of Visual Evoked Potential, Electroretinography and Electrooculography in Normal Subjects Using MonPack 3 System.
Seong Gyu MIN ; Young Hoon LEE ; Sun Young JIN
Journal of the Korean Ophthalmological Society 2014;55(11):1693-1697
PURPOSE: We present the results of visual evoked potential (VEP), electroretinography (ERG), and electrooculography (EOG) in normal subjects using the Mon-pack 3 system (Metrovision). METHODS: VEP, ERG, and EOG were obtained in 92 normal eyes. The measurements followed the International Society for Clinical Electrophysiology of Vision (ISCEV) standardization protocol. In VEP, the standard electrode was placed on the forehead and the active electrode was attached on the occiput. In ERG, a 20-minute dark adaptation was performed after mydriasis, and an ERG-jet electrode was used. EOG was measured by attaching an electrode to each medial canthal skin. Each latent period and electric potential was measured with average, standard deviation, median, and 95% confidencenterval (95% CI). RESULTS: The mean P100 latency in pattern VEP was 104.36 ms, and P100 latency in flash VEP was 116.71 ms. For the maximal ERG response, the implicit times of a and b waves were 22.65 ms and 44.58 ms, respectively and the amplitude of a and b waves were 274.09 microv and 489.52 microv, respectively. For the ERG cone response, the implicit time of a and b waves were 18.21 ms and 33.40 ms, respectively, and the amplitude of a and b waves were 35.87 microv and 104.42 microv, respectively. The mean ERG oscillitatory potential was 285.53 microv. The average EOG Arden ratio was 2.54. CONCLUSIONS: VEP, ERG, and EOG results from normal subjects using the Mon-pack 3 system can be applied to the diagnosis of retina and optic nerve disease and basic research.
Dark Adaptation
;
Diagnosis
;
Electrodes
;
Electrooculography*
;
Electrophysiology
;
Electroretinography*
;
Evoked Potentials, Visual*
;
Forehead
;
Mydriasis
;
Optic Nerve Diseases
;
Retina
;
Skin
6.Mental Health and Health Risk Behaviors of Multicultural Adolescents according to Their Mothers' Native Country: Using Data from the 11th (2015) Korea Youth Risk Behavior Web-Based Survey 2015.
Hyeon Ok JU ; So Yeon PARK ; Jaeyoung LEE
Child Health Nursing Research 2017;23(1):101-110
PURPOSE: The purpose of this study was to analyze the mental health and health risk behaviors of multicultural adolescents according to their mothers' native country. METHODS: For this study raw data from the 11th Youth Health Behavior Online Survey (2015) was examined. Mental health and health risk behaviors for 62,985 adolescents were analyzed according to their mothers' native country. Collected data were analyzed with the SPSS program using descriptive statistics and logistic regression analysis, to which the complex sample design was applied. RESULTS: The odds ratio of depression in multicultural adolescents compared to Korean adolescents was 44.92 (CI: 5.77-349.59) for adolescents whose mothers came from Cambodia and 3.00 (CI: 1.57-5.76) for adolescents whose mothers came from North Korea. The odds ratio of attempted suicide was 14.73 (CI: 3.09-70.22) for adolescents whose mothers came from Cambodia and 8.63 (CI: 3.45-21.62) for adolescents whose mothers came from North Korea. The odds ratio of problematic drinking in multicultural adolescents was 7.47 (CI: 1.71-32.67) for adolescents whose mothers came from Mongolia. CONCLUSION: Findings indicate that when planning a health promotion program for adolescents from multicultural families, a customized approach should be sought taking into account the characteristics of mothers' native country.
Adolescent*
;
Cambodia
;
Cultural Diversity
;
Democratic People's Republic of Korea
;
Depression
;
Drinking
;
Health Behavior
;
Health Promotion
;
Humans
;
Korea*
;
Logistic Models
;
Mental Health*
;
Mongolia
;
Mothers
;
Odds Ratio
;
Risk-Taking*
;
Suicide, Attempted
7.Non-O1, non-O139 Vibrio cholerae bacteraemia in splenectomised thalassaemic patient from Malaysia.
Deris ZZ ; Leow VM ; Wan Hassan MN ; Nik Lah AZ ; Lee SY ; Siti Hawa H ; Siti Asma H ; Ravichandran M
Tropical Biomedicine 2009;26(3):320-325
Vibrio cholerae infection is mainly caused acute diarrhoea disease. Bacteraemia due to non-O1 V. cholerae is rare and mainly reported in liver cirrhotic patients. We report one case of non-O1 V. cholerae bacteraemia in splenectomised thalassaemic patient who presented with septic shock secondary to abdominal sepsis. She had undergone emergency laporatomy and was managed in the intensive care unit for nine days. She was treated with meropenem and doxycyline and discharged well after fourteen days of admission. The V. cholerae was identified by API 20NE, serotype and polymerase chain reaction showed as non-O1, non-O139 strain. Besides known cholera-like toxin and El Tor hemolysin, with increasing reported cases of V. cholerae bacteraemia, there is possibility of other virulence factors that allow this organism to invade the bloodstream.
8.A Preliminary Clinical Study Of Lesion-Free And Lesion-Active Patients With Oral Lichen Planus And/Or Oral Lichenoid Reactions
Foo SY ; Lee WY ; Goh YC ; Siar CH
Annals of Dentistry 2015;22(1):21-29
Background: Oral lichen planus (OLP) which belongs to the spectrum of LP, is a commonly encounteredoral mucosal problem among patients seeking treatment in the Oral Medicine clinic. Its counterpart, orallichenoid reaction (OLR), which resembled OLP clinically and microscopically, is often encountered inthese patients as well. Although the various clinical forms of OLP/OLR are well-recognized, the diseasepattern in regards to lesion-active and lesion-free periods in these patients remains poorly characterized.Thus the aim of this study was to determine the clinical and demographic profile of those patients withactive OLP/OLR lesions and compare them with those patients who are clinically lesion-free.Materials and methods: The study subjects comprised 20 patients who attended the Oral MedicineClinic at the Faculty of Dentistry, University of Malaya for follow-up appointments/management. Theywere interviewed according to a pre-designed questionnaire, and clinical examination was carried out. Allthese were conducted under the supervision of Oral Medicine specialists. OLP was diagnosed accordingto the internationally accepted criteria.Results: The cohort consisted of predominantly female (n=14; 70%) and Chinese (n=9; 45%) patients,with an overall age range of 26-79 years (median, 56 years). Fifteen (75%) patients presented withactive OLP/OLR lesions and the remaining 5 (25%) were lesion-free. The lesion-active group comprised3 (15%) males and 12 (60%) females whereas the lesion-free had 3 (15%) males and 2 (10%) females.Reticular LP was the most common type (n=21/35; 60%) and the gingiva was the most prevalent site(n=21/46; 45.65%). Social habits, medical histories and medications were not significantly differentbetween lesion-active and lesion-free OLP patients.Conclusions: Findings suggest that demographic parameters, lifestyle and systemic diseases do notappear to influence the disease pattern and lesion severity in OLP.
9.Diagnosis and Treatment of Hirschsprung's Disease in Korea: Current Status of 1992
SY YOO ; SY KIM ; WK KIM ; IK KIM ; JE KIM ; KW PARK ; WH PARK ; JS PARK ; YT SONG ; SM OH ; OS LEE ; MD LEE ; SC LEE ; SI CHANG ; SY CHUNG ; ES CHUNG ; PM JUNG ; JS JOO ; KJ CHOI ; SO CHOI ; SH CHOI ; YS HUH ; EH HWANG
Journal of the Korean Association of Pediatric Surgeons 1996;2(1):33-41
This report present the result of the national survey of pediatric surgeons' preferences on diagnosis and treatment of Hirschsprung's disease(HD) carried out in 1993. The questionnaires were sent to twenty-seven members of the Korean Association of Pediatric Surgeons (KAPS) working in twenty-four institutions. The questionnaires were designed to determine the individual surgeon's preference for the methods of diagnosis and treatment of the disease. Twenty-three pediatric surgeons from twenty institutions returned completed forms. The total number of patients diagnosed with HD in 1992 was 190 in this group. The estimated incidence of HD was 1/3,900. The most important symptom was delayed meconium passing and the most preferred diagnostic procedure was barium study. Anorectal manometric examination was carried out by 13 pediatric surgeons and 19 confirmed the diagnosis before operation by rectal biopsy, 12 with full-thickness biopsy and 7 with suction. Frozen section biopsy during operation was done by 22 surgeons. Eight surgeons did one stage operation if the age of the patient is suitable. Definitive operation was usually done at the age of 6 to 11 months. The most preferred operation was Duhamel procedure done by 19. Enterocolitis was the most serious complication of HD. Most of patients had normal continence within 6 to 12 months after operation. The follow-up period was less than 6 years in 16 surgeons. The results were presented at the 9th annual meeting of KAPS in June of 1993. This is the first national survey of HD and it can provide guidelines of diagnosis and treatment of Hirschprung's disease even though it is not a detailed study of patient data.
Barium
;
Biopsy
;
Diagnosis
;
Enterocolitis
;
Follow-Up Studies
;
Frozen Sections
;
Hirschsprung Disease
;
Humans
;
Incidence
;
Korea
;
Meconium
;
Suction
;
Surgeons
10.Clinical effects of recombinant human granulocyte-macrophage colony-stimulating factor(rh GM-CSF) in patients with leukopenia after cancer chemotherapy.
Jae Sung HONG ; Soo Kyung PARK ; Kwan Hoon LEE ; Sy Sueng RHU ; Jae Keun JUNG ; Sung Eun NAMGOONG ; Seung Jo KIM ; Hun Young LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):2993-2999
No abstract available.
Drug Therapy*
;
Humans*
;
Leukopenia*