2.Studies on the intradermal reactions with the fractions of Ascaris lumbricoides.
The Korean Journal of Parasitology 1967;5(1):17-34
The intradermal studies with the fraction of Ascaris lumbricoides and Toxocara canis were performed to human and dog, and the following results were observed. Wheal and erythema were appeared in the cases of ascaris infection or who had past history, but not in the ascaris free before. The size of wheal reached to peak 30 minutes after the injection. The crude antigen had specificity and showed no cross reaction. The crude antigen cause the strongest and largest reaction than the other substances; protein, polysaccharide and the mixed antigen. No cutaneous reaction was observed with the fraction of polysaccharides. The size of wheal did not parallel with the worm burden. The skin reaction was appeared four weeks after the infection.
parasitology-nematode-Ascaris lumbricoides
;
Toxocara canis
;
immunology-crude antigen-skin test
;
dog
;
protein
;
polysaccharide
;
antigen
3.How Can the Western and Oriental Ideas of Illness Communicate?.
Journal of the Korean Medical Association 1997;40(3):283-287
No abstract available.
4.Immunoblotting analysis and complement binding capacity of bullous pemphingoid autoantibody.
Korean Journal of Dermatology 1993;31(4):465-473
BACKGROUND: Bullous pemphigoid is a rare autoimmune bullous disease characterized by subepidermal bulla. The serum of these patients contains detectable autoantibodies which bind to the hemidesmosome of the basement membrane zone. It is well known that there are two bullous pemphigoid antigen molecules, 230KD and 170KD protein. Serum studies in Caucasian patients show that 70-80% of the patients recognize 230KD antigen while 10-30% recognize 170KD antigen, In contrast, in herpes gestationis, which is an autommune-mediated bullous disease of pregnancy, 90% of the patients recognize 170KD and 10% recognize 230KD antigen, The autoantibody of herpes gestationis(HG factor) has a strong complement binding capacity and it may share the same epitope as the antibody of bullous pemphigoid patients which recognize 170KD antigen. OBJECTIVE: The purpose of this study was to characterize the clinical and histological manifestations of Korean patients with bullous pemphigoid and to characterize the autoantibodies of Korean bullous pemphigoid patients by immunoblotting. We also wished to compare the characteristics of the antibodies with that of American bullous pemphigoid patients, and to elucidate the hypothesis that the bullous pemphigoid autoantibody against 170KD protein has the same strong complement binding capacity as the herpes gestationis autoantibody. MEHTODS: We investigated the clinical and histological characteristics of 9 Korean patients and also performed a complement binding capacity and immunoblotting study on the sera of 9 Korean patients and 16 American patients. RESULTS: 1. Korean bullous pemphigoid patients clinically showed polymorphic skin eruption in addition to tense bullae. They frequently showed pruritic erythematous patches and urticarial plaques. Histologically, infiltration of subepidermal bullae with eosinophils, neutrophils and lymphocytes were observed in all patient's specimen, in which eosinophils were the most predominant cells, Uncommonly, eosinophilic spongiosis, vaculoar degeneration of basal cells were observed. These observations did not have any particular characteristics or racial differences compared to those patients reported in Western literature. 2. In the immunoblotting study of Korean bullous pemphigoid patients, 7 of 9 sera(785) recognized 230KD antigen and, also, 7 of 9 sera(78%)recognized 170KD antigen, In contrast, 15 of 16 American patients sera (94%) recognized 230KD antigen and 6 of 16 patients sera(38%) recognized 170KD antigen. The high incidence of the autoantibody against 170KD in Korean patients shows possible racial differences in autoantibody formation. 3. There was no relationship between the types of autoantibodies typed by immunoblotting and the complement binding capacity. In other words, autoantibodies against 170KD antigen do not carry the same potential as autoantibodies of herpes gestationis for the complement biding capacity, CONCLUSION: The above results suggest tha there may be racial difference in bullous pemphigoid autoantibodies between Korean bullous pemphigoid patients and American patients. In conclusion, We conclude that 170KD bullous pemphigoid antibodies do not always have the same strong complement binding as herpes gestationis antibody.
Antibodies
;
Autoantibodies
;
Basement Membrane
;
Complement System Proteins*
;
Eosinophils
;
Female
;
Hemidesmosomes
;
Humans
;
Immunoblotting*
;
Incidence
;
Lymphocytes
;
Neutrophils
;
Pemphigoid Gestationis
;
Pemphigoid, Bullous
;
Pregnancy
;
Skin
;
Transcutaneous Electric Nerve Stimulation
5.Thyriod Function Studies in Children with Nephrotic Syndrome.
Journal of the Korean Pediatric Society 1988;31(8):1037-1047
No abstract available.
Child*
;
Humans
;
Nephrotic Syndrome*
6.Widespread Persistent Erythemas and the 'Holster Sign' in Dermatomyositis.
The Journal of the Korean Rheumatism Association 2007;14(1):101-102
No Abstract available.
Dermatomyositis*
;
Erythema*
7.Inflammatory Pseudotumor of the Liver: A case report.
Sang Chirl LEE ; Chang Su LEE ; Chan Young LEE
Korean Journal of Gastrointestinal Endoscopy 1987;7(1):87-89
The term "collagenous colitis" was coined by Lindstrom in 1976 to describe the patient with chronic watery diarrhea who had normal rectal mucosa by proctoscopy but who had a thick subepithelial collagenous deposit on biopsy, and now collagenous colitis is recognized as one of the more common causes of chronic diarrhea of obscure origin. But in this country only a few case has been reported. We have seen a 68-year-old man with chronic watery diarrhea with abdominal pain. Physical examination, laboratory and radiologic studies were no abnormal finding. Colonoscopy disclosed grossly normal mucosa through the entire colon but by histologic examination there are chronic inflammation in the lamina propria and thickened subepithelial collagen layer. Symptoms and pathologic findings of patient improved after treatment with sulfasalazine and prednisolone. (Korean J Castraintest Endosc 17: 79-84, 1997)
Abdominal Pain
;
Aged
;
Biopsy
;
Colitis, Collagenous
;
Collagen
;
Colon
;
Colonoscopy
;
Diarrhea
;
Granuloma, Plasma Cell*
;
Humans
;
Inflammation
;
Liver*
;
Mucous Membrane
;
Numismatics
;
Physical Examination
;
Prednisolone
;
Proctoscopy
;
Sulfasalazine
8.A Case of Miliaria Crystallina.
Korean Journal of Dermatology 2015;53(8):663-664
No abstract available.
Fentanyl
;
Intensive Care Units
;
Miliaria*
9.A study on fracture strength and color by the design of metal coping in ceramo metal crown.
Myung Ho LEE ; Young Chan JEON
The Journal of Korean Academy of Prosthodontics 1992;30(1):103-124
No abstract available.
Crowns*
10.Effect of Main Pulmonary Artery Constriction on the Right Ventricle in Rabbits.
Journal of the Korean Pediatric Society 1995;38(8):1087-1092
No abstract available.
Constriction*
;
Heart Ventricles*
;
Pulmonary Artery*
;
Rabbits*