1.Comparison of ultrasound-measured properties of the common carotid artery to tobacco smoke exposure in a cohort of Indonesian patients
Yu R. ALLEN ; Hasjim BIMA ; Yu E. LUKE ; Gabriel CHRISTOPHER ; Anshus ALEXANDER ; Lee B. JONATHAN ; Louthan J. MICHAEL ; Kim C. ESTHER ; Lee KATRINA ; Tse CHRISTINA ; Keown THOMAS ; Lahham SHADI ; Alvarado MAILI ; Bunch STEVEN ; Gari ABDULATIF ; Fox Christian J.
World Journal of Emergency Medicine 2017;8(3):177-183
BACKGROUND:The purpose of this study was to use point-of-care ultrasound (POCUS) to investigate the relationship between tobacco smoke exposure and the characteristics of the common carotid artery (CCA). The effect of both primary and secondary smoking on CCA properties was evaluated. METHODS:We performed a prospective cross-sectional study across 20 primary care clinics in Bandung, West Java, Indonesia in July 2016. Point of care ultrasound was performed on a convenience sample of Indonesian patients presenting to clinic. The CCA wall stiffness and carotid intima-media thickness (CIMT) were measured during diastole and systole. These measurements were correlated with smoke exposure and cardiovascular disease. RESULTS: We enrolled 663 patients in the study, with 426 patients enrolled in the smoking category and 237 patients enrolled in the second-hand smoke category. There was an overall positive correlation with the measured lifestyle factors and the ultrasound-measured variables in the group of individuals who smoked. For all variables, age seemed to contribute the most out of all of the lifestyle factors for the positive changes in CIMT and CCA wall stiffness. CONCLUSION:Our data yielded correlations between CCA properties and cardiovascular risk, as well as between CIMT and arterial stiffness. We were also able to demonstrate an increase in thickness of the CIMT in patients who have been exposed by tobacco through the use of ultrasound. Further large scale studies comparing patients with multiple cardiac risk factors need to be performed to confirm the utility of ultrasound findings of cardiovascular disease and stroke.
2.Evaluation of a point of care ultrasound curriculum for Indonesian physicians taught by first-year medical students
Lee B. JONATHAN ; Tse CHRISTINA ; Keown THOMAS ; Louthan MICHAEL ; Gabriel CHRISTOPHER ; Anshus ALEXANDER ; Hasjim BIMA ; Lee KATRINA ; Kim ESTHER ; Yu LUKE ; Yu ALLEN ; Lahham SHADI ; Bunch STEVEN ; Alvarado MAILI ; Gari ABDULATIF ; Fox C. JOHN
World Journal of Emergency Medicine 2017;8(4):281-286
BACKGROUND: The purpose of this study was to assess the short-term efficacy of a 4-week ultrasound curriculum taught by American first-year medical students to general practitioners working in public health care clinics, or puskesmas, in Bandung, Indonesia. METHODS: We performed a prospective, observational study of Indonesian health care practitioners from public clinics in Bandung, Indonesia. These practitioners were enrolled in a 4-week ultrasound training course taught by first-year American medical students. A total of six sessions were held comprising of 38 ultrasound milestones. A pre-course and post-course written exam and practical exam was taken by each participant. RESULTS: We enrolled 41 clinicians in the course. The average pre-course exam score was 35.2% with a 2.4% pass rate, whereas the average post-course exam score was 82.0% with a 92.7% pass rate. The average practical score at the completion of the course was 83.2% (SD=0.145) with 82.9% of the class passing (score above 75.0%). CONCLUSION: Our data suggests that first-year medical students can effectively teach ultrasound to physicians in Indonesia using a 4-week intensive ultrasound training course. Future studies are needed to determine the amount of training required for proficiency and to evaluate the physicians' perceptions of the student-instructors' depth of knowledge and skil in point of cаre ultrаsound.
3.The effect of cycled light exposure on clinical outcomes of preterm infants admitted in neonatal intensive care units
Roffell D. Felisilda ; Katrina Mae G. Lee ; Christine Corina Grace L. Basilla
The Philippine Children’s Medical Center Journal 2025;21(1):27-41
BACKGROUND:
Hospitalization in neonatal intensive care units (NICU) exposes preterm infants to adverse stimuli, including continuous 24-hour lighting. There is currently no standardized NICU layout advised for the best development of preterm neonates. This meta-analysis aimed to assess the impact of cycled light (CL) exposure on clinical outcomes in premature infants admitted to NICU as synthesized in previous studies.
MATERIALS AND METHODS:
This meta-analysis protocol was developed following the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. A search was performed in PubMed/MEDLINE, EMBASE, Scopus, and Cochrane databases using the MeSH/key words: ―light exposure‖ AND pre-term AND cycled AND (RCT OR trials OR ―randomized controlled trial). The pooled Mean Difference with corresponding 95% CI was computed for weight gain, duration until start of enteral feeding, and duration of ICU stay using the Mantel–Haenszel random-effect model.
RESULTS:
Nine studies were included. The pooled mean difference showed that among preterm infants who had cycled light exposure, average daily weight gain (MD=6.24 grams, 95%CI=1.36 to 11.13, p=0.01) was significantly higher than those with continuous light exposure. The average time to start enteral feeding (MD=-3.84 days, 95%CI=-7.56 to -0.13, p=0.04) and average ICU stay (MD=-8.43 days, 95%CI=-12.54 to -4.31, p<0.0001) among neonates who had cycled light exposure were significantly shorter.
CONCLUSION
Benefits were seen in preterm infants when exposed to cycled light as opposed to continuous light. CL exposed infants showed a daily weight gain that was 6.24 grams higher, on average, and began enteral feeding nearly 4 days sooner. It led to a decrease in the duration of ICU stay by around 8 to 9 days on average. Further trials to determine the impact of cycled light exposure on morbidity and mortality among preterm neonates is recommended.
Human
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Male,Female
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Systematic review
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Meta-analysis
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Infant, Premature
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Intensive care units, Neonatal
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Intensive care, Neonatal
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Light
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Lighting
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Critical care
4.The role of public health dietary messages and guidelines in tackling overweight and obesity issues
Yi Yi Lee ; David Tan ; José ; Siri ; Barry Newell ; Yi Gong ; Katrina Proust ; Terry Marsden
Malaysian Journal of Nutrition 2020;26(No.1):31-50
Overweight and obesity in Malaysia pose serious threats to health. Prevalence has escalated to alarming levels in recent decades despite a multitude of public health dietary messages geared towards obesity prevention and health promotion. Gaps between health messages, messengers, and the public must be identified and closed to effectively combat obesity and overweight. This review article aims to examine public health dietary messages, guidelines, and programmes for the prevention of obesity in Malaysia, and explore potential reasons for the continued rise in its prevalence. Public health dietary communication in Malaysia has progressed and improved substantially over the years. However, most messages have been designed for the general audience, with little consideration of differences in physical, social, cultural, and environmental backgrounds, and varying levels of comprehension. We offer several recommendations to increase the effectiveness of public health dietary messages in fighting the obesity epidemic, based on a cross-sectoral, place-based approach that recognise the complexity of the underlying causes of obesity.
5.Weight control practices of Philippine National Wushu Sanda Athletes: A study protocol.
Karen Leslie LEE-PINEDA ; Karen Anne ALEJO ; Paolo Rafael Santamaria ABELA ; Matthew AGUADO ; Ana Katrina AMBAL ; Marco Sebastian ATOS ; Miguel Angelo Castillo BALANKIG ; Sean Brix CUISON ; Ethaniel Tichangco ENCARNACION
Philippine Journal of Allied Health Sciences 2025;9(1):68-74
BACKGROUND
Combat sports are intense and physically demanding, and healthy weight control practices are necessary to ensure a safe and fair competition for all athletes involved.
OBJECTIVEThe study will determine the dietary and non-dietary weight control practices of Philippine National Wushu Sanda athletes. It will also aim to explore the perceived effects of these practices on performance and well-being.
METHODOLOGYA qualitative study using semi-structured interviews will be used to gain insights into the athletes' experiences, habits, and practices regarding their weight control practices. The semi-structured questionnaire will focus on daily food intake, weight control practices, and their effects on performance and well-being. Thematic data analysis will be used to analyze the data.
EXPECTED RESULTSWeight control practices of Wushu Sanda Athletes vary depending on the training phase. Both dietary practices, such as water intake, skipping meals, and food choices, and non-dietary practices, such as intense training and sweat suits, are expected to be observed to achieve their desired weight. These practices are anticipated to have been influenced by their coaches and senior athletes, having both positive and negative effects on the athlete’s physical, mental, and psychological well-being.
Human ; Martial Arts ; Sports ; Athletes
6.Antimicrobial activity of Ardisia serrata (Cavs.) Pers. ethanolic and aqueous leaf extract on the growth and biofilm formation of selected bacterial isolates
Patrick Josemaria DR. Altavas ; Alfonso Rafael G. Abaya ; Remo Vittorio Thaddeus D. Abella ; Danna Lee A. Acosta ; Angelica C. Aguilar ; Camille Anne V. Aguinaldo ; Katrina Loise L. Aguirre ; Catherine Therese C. Amante ; Karen B. Amora ; Glen Aldrix R. Anarna ; Rafael T. Andrada ; Gere Ganixon T. Ang ; Jeram Caezar R. Angobung ; Angelo V. Aquino II ; Dennielle Ann P. Arabis ; Hannah Luisa G. Awitan ; Mary Faith D. Baccay ; Chryz Angelo Jonathan B. Bagsic ; Tomas V. Baldosano Jr. ; Cecilia C. Maramba-Lazarte
Acta Medica Philippina 2024;58(18):91-97
Background:
Ardisia serrata (Aunasin) is an endemic Philippine plant of the family Primulaceae, with several studiesshowing the genus Ardisia as having potential antibacterial, antiangiogenic, cytotoxic, and antipyretic properties.
Objective:
This study aims to determine the antibacterial and antibiofilm-forming activity of Ardisia serrata ethanolic and aqueous extracts on Escherichia coli, Methicillin-Sensitive Staphylococcus aureus (MSSA), and Methicillin-Resistant Staphylococcus aureus (MRSA).
Methods:
This is an experimental study testing the activity against bacterial strains of E. coli, MSSA, and MRSA using ethanolic and aqueous extracts of A. serrata leaves. Microtiter susceptibility and biofilm inhibition assays were done with two-fold dilutions of the extract against the selected strains using spectrophotometry with optical density (OD) at 600 nm and 595 nm, respectively, to quantify bacterial growth and biofilm inhibition. The bacterial susceptibility and biofilm inhibition activity was reported as percent inhibition (PI). Minimum inhibitory concentration (MIC), and minimum biofilm inhibition concentration (MBIC) values were obtained using logarithmic regression of the PI values.
Results:
A. serrata ethanolic extracts showed weak growth inhibitory activity against MSSA and MRSA with minimum inhibitory concentration (MIC) values of 2.6192 and 3.2988 mg/mL, respectively, but no biofilm inhibition activity was noted, while the aqueous extracts exhibited negligible biofilm inhibition activity against MSSA and MRSA with minimum biofilm inhibition concentration (MBIC) values of 13.5972 and 8964.82 mg/mL, respectively, and with no growth inhibition activity. Both ethanolic and aqueous extracts showed no growth inhibition and biofilm inhibition activities against E. coli.
Conclusion
Staphylococcus aureus is susceptible to the bioactivity of the leaf extracts of A. serrata and has potential to be used as an antibacterial in the treatment of infectious diseases.
Methicillin-resistant Staphylococcus aureus
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Escherichia coli
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natural product
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biological products