1.Dermatomyositis: Clinical Profile And Association with Malignancies in 43 Patients
Yap EWY ; Lee BS ; San VE ; See CKL ; Wong NKL ; Choon SE
Malaysian Journal of Dermatology 2014;33(-):2-8
Introduction: Dermatomyositis is a rare idiopathic inflammatory myopathy with distinctive cutaneous
manifestations. This study aims to determine the demographic characteristics, clinical features and
associated malignancies in patients with dermatomyositis.
Materials & Methods: Dermatomyositis is a rare idiopathic inflammatory myopathy with distinctive
cutaneous manifestations. This study aims to determine the demographic characteristics, clinical
features and associated malignancies in patients with dermatomyositis.
Results: Forty-three cases were identified, with female to male ratio of 1.26:1. Mean age of onset was
47.8 +18.0 years. Malay and Chinese patients made up the bulk of the patients, contributing 53.5% and
44.2% respectively. Photosensitive rash was the commonest clinical presentation, occurring in 55.8%
of the patients, followed by Gottron’s papules (46.5%), heliotrope rash (44.2%), alopecia (23.3%)
and calcinosis (9.3%). Median Creatinine Kinase level was 293IU/L (interquartile range 89-1166),
Lactate Dehydrogenase 641IU/L (interquartile range 459-986) and Aspartate Transaminase 70.5IU/L
(interquartile range 41.5-156.25). Concomitant malignancies occurred in 14 patients (32.5%), the
commonest being nasopharyngeal carcinoma (6 patients), followed by gastrointestinal tumours (3
patients), breast cancer (2 patients) and lymphoproliferative disorders (2 patients) and lung cancer
(1 patient). Of these 14 patients, malignancies were detected in 10 patients within the first year, and
2 patients within the second year after diagnosis of DM. Two patients had malignancies diagnosed
within 6 months prior to the diagnosis of DM. Malignancy accounts for 64.7% of the 17 mortalities
recorded. The proportion of Malay patients with paraneoplastic dermatomyositis with respect to the
total number of Malay new clinic attendees over the past 13 years is 7 in 10,000 persons whereas in
Chinese patients, the proportion is 15 in 10,000 persons.
Conclusion: Malignancy is found in about a third of all patients, with Chinese predisposition seen.
This could explain why nasopharyngeal carcinoma is most prevalent in our centre.
2.A study on the Korean dental education system
Bo Young PARK ; Won il BHANG ; Jihyun LEE ; Jung Joon IHM ; Ho Beom KWON
Journal of Korean Academy of Oral Health 2019;43(2):83-91
OBJECTIVES: This study aimed to propose criteria for evaluating the validity of dental education systems in Korea and suggest future directions for their improvement. METHODS: We looked into dental educational institutions and derived criteria for analysis and comparison of dental education systems in Korea. Using analytical methods, we compared the strengths and weaknesses of each education system, and suggested core areas of improvement. RESULTS: Considering the demands placed on the Korean dental education sector, it is desirable to have an integrated education system that includes the preliminary and main courses, comprehensive training linking the basic medicine and clinical practice, and complete career guidance. CONCLUSIONS: A good dental education system is one that meets the educational goals set by a dental school. If the goal is to train a student to be a good dental practitioner, a 2+4 or 4+4 system is recommended, while a 3+4 model is more suitable when the objective is to train students to be researchers.
Education
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Education, Continuing
;
Education, Dental
;
Humans
;
Korea
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Schools, Dental
3.Characteristics of Defecation Function Related Quality of Life According to Cancer Location in Colorectal Cancer Survivors
Okimitsu OYAMA ; Dong-Hyuk PARK ; Mi-Kyung LEE ; Ji-yong BYEON ; Eun Byeol LEE ; Jae-Youn CHUNG ; Hye Jeong JUNG ; Jisu PARK ; Taeil KIM ; Sun Ha JEE ; Nam Kyu KIM ; Justin Y JEON
Asian Oncology Nursing 2022;22(4):225-234
Purpose:
The purpose of this study is to explore defecation functions related quality of life (QoL) according to the location of cancer in colorectal cancer survivors.
Methods:
A total of 120 colorectal cancer survivors (67 colon vs. 53 rectum, mean age: 55.3±10.3 years, 46.7% male) who completed treatment were recruited from a tertiary hospital. QoL and defecation function related QoL were surveyed using the European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) and EORTC QLQ- colorectal cancer specific core (CR29) questionnaire. Physical activity (PA) levels of participants were surveyed using a global PA questionnaire.
Results:
There was no statistical difference in general QoL according to the location of cancer, but significant differences were observed in defecation function related QoL. When cancer location is closer to the anus, survivors experience more defecation dysfunction, negatively associated with QoL (Hemicolectomy: 67.71±14.07, anterior resection: 92.22±15.18, lower anterior resection: 151.85±17.20, and ultra-low anterior resection: 263.73±42.69).
Conclusion
When location of cancer is closer to the anus, colorectal survivors experience significantly more defecation dysfunction and poorer QoL. Strategies to reduce defecation dysfunction according to the location of cancer among colorectal cancer patients should be developed.
4.Dynamic Fixation versus Static Screw Fixation for Syndesmosis Injuries in Pronation External Rotation Ankle Fractures: A Retrospective Case Control Study
Lim CM ; Choi SW ; Kim BS ; Lee SJ ; Kang HS
Malaysian Orthopaedic Journal 2023;17(No.3):48-58
Introduction: The current standard treatment for ankle
syndesmosis injury is static screw fixation. Dynamic fixation
was developed to restore the dynamic function of the
syndesmosis. The purpose of this study was to determine that
which of static screw fixation and dynamic fixation is better
for treatment of ankle syndesmosis injury in pronationexternal rotation fractures.
Materials and methods: Thirty patients were treated with
dynamic fixation (DF group) and 28 patients with static
screw fixation (SF group). The primary outcome was
Olerud–Molander Ankle Outcome Score. The secondary
outcome were Visual Analogue Scale score and American
Orthopedic Foot and Ankle Society score, radiographic
outcomes, complications and cost effectiveness. To evaluate
the radiographic outcome, the tibiofibular clear space,
tibiofibular overlap, and medial clear space were compared
using the pre-operative and last follow-up plain radiographs.
To evaluate the cost effectiveness, the total hospital cost was
compared between the two groups
Results: There was no significant difference in primary
outcome. Moreover, there were no significant difference in
secondary outcome including Visual Analogue Scale score
and American Orthopedic Foot and Ankle Society score and
radiographic outcome. Two cases of reduction loss and four
cases of screw breakage were observed in the SF group. No
complication in the DF group was observed. Dynamic
fixation was more cost effective than static screw fixation
with respect to the total hospital cost.
Conclusion: Although dynamic fixation provided similar
clinical and radiologic outcome, dynamic fixation is more
cost effective with fewer complications than static screw
fixation in ankle syndesmosis injury of pronation-external
rotation fractures.