The immune status in 26 typhoid fever patients has been studied. They are 15 males, 112 females from 16 to 30 years old. This study reveals that: during the fever period of the disease, pronounced disturbances in immune, homeostasis are observed, which are manifested by lymphopenia, with a considerable rise of natural killer (NK) and active rosette forming cells (Ea). At the period of convalescence, the parameters decreased to normal value, except a mild increase of immunoglobulin (IgM, IgG)
Typhoid Fever ; Autoimmunity

79 serum samples of tetanus patients admitted to The Institute for research on Clinical Medicine and Tropical Diseases from November 1996 to May 1997 were analysed by technique of inoculation in mice. The results showed that: 1) Free circulating tetanus toxin was detected in 19% of cases with 5.1% of cases with 5.1% of cases of low toxin concentration and 13.9% of cases of high toxin concentration. All them are negative after 5 days of ATS injection (Anti Tetanus Serum) with 6000-9000 IU (M.I). 2) The presence of free circulating tetanus toxin in the blood was not related to infectious condition of the wound (P>0.05). 3) Mortality in the group with positive free tetanus toxin (60%) are higher significantly (p<0.01) than the negative one (20.3%). So, free circulating tetanus toxin in the blood had a severe prognostic value in tetanus patients. 4) Using ATS was necessary for the treatment of tetanus patients. 5) Serum antitoxin concentration in most of tetanus patients (90%) was lower than the 'protective level' (<0.01IU/ml).
Tetanus ; Bood

79 sera of tetanus patients (Institute for Clinical Research in Tropical Diseases 1966, 1967, 1996 to 1997 were investigated for circulating toxin, using the mouse inoculation technique). Results: free circulating tetanus toxin was detected in 19,0% cases, among them 5,1% had low toxic concentration and 13,9% had high toxic concentration. The presence of free circulating tetanus toxin in the blood was not related to the infectious condition of the wound at admission. The mortality in the group with positive free circulating tetanus toxic was higher 60% than this in the negative one. So the presence of free circulating tetanus toxin in the blood had a prognostic value in tetanus patients. The use of tetanus antitoxin was necessary in the treatment of tetanus patients to neutralize free circulating tetanus toxin.
Tetanus ; Bood

A cross sectional retrospective study was conducted on 290 patients aged 19- 78 years old at Hung Vuong Hospital from July 2000 to July 2003, with PAP's smear, colposcopy and biopsy. Result showed that non benignant smear accosted for 16,9% non benignant colposcopy 28,6%, non benignant biopsy 35,2%. In comparing with the number of patients submited to consultation, the rate of smear 78,04% among then 0,13% were detected with any pathology and the rate of colposcopy 20,91% and 0,98% with any pathology
Vaginal Smears ; diagnosis ; colposcopy ; Biopsy ; Uterine Cervical Diseases

A randomized controlled trial was carried out on two groups of patients who were received either Flagystatine (nystatin 1000000 UI/metronidazol 500 mg) or Neo Penotran (miconazol 100mg/metronidazol 500 mg), twice a day for 7 days. Gynecological and microbiological assessments were carried out before treatment and 14 days after the first visit. In Flagystatine and Neo Penotran groups, clinical cure rates were 42% and 77.9% respectively; microbiological cure rates were 68.2% and 72.1%. In Neo Penotran group, functional symptoms were reduced more than organic symptom (84.8% and 79.1%, respectively). This difference was not so remarkable in Flagystatine group (64.8% and 65.95, respectively). Side effects of Neo Penotran were insignificant. Neo Penotran therapy without supportive treatment had higher efficacy in vaginitis at dosage of two pill a day in 7 days. The drug showed effects in both of function symptoms and organic symptoms, in clinical and paraclinical
Vaginitis ; Therapeutics

Fetal chromosomal anomalies can be of number or of structure, on autosomal or on sex chromosomes. Prevalence of anomalies was approximately 1/150 of live births. However, some chromosomal anomalies did not show abnormal phenotypes. Abnormality of chromosomes was a main cause of spontaneous abortion and stillbirth, especially early abortion. Most of anomalies happened during gametogenesis of parent having normal chromosomes. The others were inherited by abnormalities from parent who had abnormal genotype but normal phenotype. Chromosomal anomalies are diagnosed by recognizing abnormal chromosome. Diagnosis was recommended when abnormal ultrasound was detected or when there were abnormality in history of mother and family. Chromosomal anomalies increased also with maternal age
Chromosome Disorders ; Pregnancy

Report one case of pregnant woman aged 29 years old, with history of spontaneous abortion 1 year ago, without other medical condition. In this gestation, the last menstruation was on September, 26th 2004, and expected delivery time on July, 3rd 2005, weight gain was normal, and fetus was normal clinically. Ultrasonographic finding showed polyhydramnios and syndactyly on the right hand. Amniotic paracentesis for FISH test result revealed trisomy 18 disorder. This pregnant woman was indicated gestative cessation. Baby was born after 31st of pregnancy, Apgar’s score: 3/4, weight of 1100g, with syndactyly on the right hand, abnormal heels and face (low-set ears, micrognathia), and dead after 3 days
Trisomy ; Prenatal Diagnosis ; Case Reports

54 patients with acute viral hepatitis of which hepatic coma (8), uncompensate cirrhosis (17) and liver cancer (14) participated to a study have shown that the serum gamma glutamyl transpeptidase ((-GT) activity was slightly increased in patients with viral hepatitis coma and uncompensate cirrhosis. This was a bad sign the (-GT was highly increased in patients with liver cancer. The average serum (-GT activity was increased about 3 times in the acute viral hepatitis. But diagnostic value of (-GT was lower than this of SGPT
Liver Diseases ; Serum ; gamma-Glutamyltransferase ; Hepatic Encephalopathy

54 patients with acute viral hepatitis (8 of those having hepatic coma), 17 patients with unrecovered cirrhosis and 14 patients with hepatoma who were admitted in Bach Mai Hospital form March 1996 to May 1997 were involved in this study. Results showed that serum -GT level is often normally or lightly increased in fulminant hepatic failure and in unrecovered cirrhosis. This suggests that monitoring serum -GT may help to prognosticate for patient with acute viral hepatitis of cirrhosis. Serum -GT activity increases in hepatoma, so the estimation of this enzyme may help to diagnose the disease. Serum -GT activity increases in acute viral hepatitis but is less significance than serum transaminase (SGPT) in diagnosing the disease.
Liver Diseases ; Serum ; gamma-Glutamyltransferase

A study on 73 patients including 27 patients with hepatitis A, 33 patients with hepatitis B and 13 patients with hepatitis C in the Institute of Clinical Medicine and Tropical Disease during 1990, 1993, 1994 has shown that most of patients with hepatitis were ages of under 40, especially under 30. The rate of hepatitis A was less than this hepatitis B; male patients were more than female patients. The common symptoms in stage before jaundice were fever, tired and anorexia. The common symptoms in stage of hepatitis jaundice were mucosal jaundice, anorexia and hepatomegaly, SGOT and SGPT were highly increased, and rate of proshombin in hepatitis B lower than this in hepatitis A and E, the blood total bilirubin in hepatitis B was highly increased.
Hepacivirus ; Hepatitis ; Lymphocytes