1.Outpatient diagnostic hysteroscopy: analysis of 429 cases
Wong Yuen-kwan ALICE ; Wong KIN-SUN ; Lok YEE-HA ; Kwok Chi-wai AARON ; Tang Chang-hung LAWRENCE
Chinese Medical Journal 1998;111(8):728-730
Objective To evaluate the diagnostic accuracy of outpatient hysteroscopy.Methods Outpatient CO2 hysteroscopy using video-camera for monitoring was performed on 429 patients from November 1995 to December 1996. The indications included post-menopausal bleeding (32.2%), menorrhagia (25.4%), irregular bleeding (24.7%), intermenstrual spotting (10.2%) and others (7.5%).Results Hysteroscopy was successfully performed on 420 (97.9%) patients. Although no anaesthetics were used, only two (0.47%) patients complained of severe pain during the procedure. Twenty-one (4.9%) patients had poor view due to submucosal fibroid or bloody view. There were no operative complications. Normal uterine cavity was found in 36.8% and atrophic endometrium in 34.7% of patients. The pathologies included submucosal fibroid (10.7%), endometrial polyp (5.8%) and fibroid polyp (2.8%). Five (1.2%) out of 429 patients were confirmed histologically to have endometrial carcinoma. No malignant lesions were missed. A total of 372 (86.7%) patients had histological confirmation of hysteroscopic findings. In 57 (13.2%) patients, the histological results did not correlate with the hysteroscopic findings.Conclusions Outpatient hysteroscopy and suction curettage is a safe, cost-effective and acceptable procedure.
2.External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke.
Ge TIAN ; Li XIONG ; Wenhua LIN ; Jinghao HAN ; Xiangyan CHEN ; Thomas Wai Hong LEUNG ; Yannie Oi Yan SOO ; Lawrence Ka Sing WONG
Journal of Clinical Neurology 2016;12(3):308-315
BACKGROUND AND PURPOSE: External counterpulsation (ECP) is a noninvasive method used to enhance cerebral perfusion by elevating the blood pressure in ischemic stroke. However, the response of the beat-to-beat blood pressure variability (BPV) in ischemic stroke patients during ECP remains unknown. METHODS: We enrolled recent ischemic stroke patients and healthy controls. Changes in the blood flow velocities in bilateral middle cerebral arteries and the continuous beat-to-beat blood pressure before, during, and after ECP were monitored. Power spectral analysis revealed that the BPV included oscillations at very low frequency (VLF; <0.04 Hz), low frequency (LF; 0.04-0.15 Hz), and high frequency (HF; 0.15-0.40 Hz), and the total power spectral density (TP; <0.40 Hz) and LF/HF ratio were calculated. RESULTS: We found that ECP significantly increased the systolic and diastolic blood pressures in both stroke patients and controls. ECP decreased markedly the systolic and diastolic BPVs at VLF and LF and the TP, and the diastolic BPV at HF when compared with baseline. The decreases in diastolic and systolic BPV reached 37.56% and 23.20%, respectively, at VLF, 21.15% and 12.19% at LF, 8.76% and 16.59% at HF, and 31.92% and 23.62% for the total TP in stroke patients, which did not differ from those in healthy controls. The change in flow velocity on the contralateral side was positively correlated with the total TP systolic BPV change induced by ECP (r=0.312, p=0.035). CONCLUSIONS: ECP reduces the beat-to-beat BPV when increasing the blood pressure and cerebral blood flow velocity in ischemic stroke patients. ECP might be able to improve the clinical outcome by decreasing the beat-to-beat BPV in stroke patients, and this should be explored further in future studies.
Blood Flow Velocity
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Blood Pressure*
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Cerebrovascular Circulation*
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Counterpulsation*
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Humans
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Methods
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Middle Cerebral Artery
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Perfusion
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Stroke*
3.A moral price for medicine.
Gabriel WONG ; Lawrence TAN ; Philip YAP
Singapore medical journal 2015;56(7):363-365
4.Complication of acute stroke: A study in ten Asian countries
Jose C Navarro ; Ester Bitanga ; Nijasri Suwanwela ; Hui Meng Chang ; Shan Jin Ryu ; Yi Ning Huang ; Lawrence Wong ; Deepak Arjundas ; Bhim Sen Singhal ; Sang Bok Lee ; Byung Woo Yoon ; N Venketasubramanian ; Hou Chang Chiu ; Niphon Poungvarin ; Kay Sin Tan ; Sardar Mohd Alam ; Duc Hinh Le
Neurology Asia 2008;13(1):33-39
Background and Objective: There is a paucity of studies looking into the frequency of complications
after stroke among Asians. We sought to determine the frequency and rate of complications among
Asians after acute stroke. Methods: Consecutive patients with acute stroke among 10 participating Asian
countries were included in the study. The frequency and timing of pre-determined complications, and
their relation to area of admission were noted. Results: Of the 1,153 patients included in the study, 423
(41.9%) developed complications within the first 2 weeks of stroke. Recurrent stroke, chest infections
and urinary tract infections were most commonly encountered, and were most frequent within the
first week of stroke onset. A lower rate of complications was noted among patients admitted at an
organized stroke unit.
Conclusion: There is a similar rate of frequency and timing of complications after acute stroke among
Asians as compared with other populations.