Objective To understand the epidemiological feature of rotavirus and humancaliciviruses in Miyun county of Bei-jing and provide theoretical basis for prevention and control.Methods Stool specimens were collected from 240 diarrhea pa-tients in 3 hospitals from April 2011 to March 2012.Enzyme linked immunosorbent assay (ELISA)and reverse transcrip-tion-polymerase chain reaction (RT-PCR)were used to detect rotavirus and humancaliciviruses respectively.Data was statis-tically analyzed.Results The positive rate of rotavirus was present in 10.3%.Positive cases mainly fell in age group 0~5. More male diarrhea patients than female were infected by humancaliciviruses (P<0.05).The positive rate of humancalicivir-uses was present 8.8%.Positive cases mainly fell in age group 19~40.Conclusion The humancaliciviruses susceptible pop-ulations were middle-aged youth and male in Miyun,the infection peak of humancaliciviruses is in autumn.The main infection of rotavirus population was babies.