Objective To learn the psychological health state,life events and coping styles of teachers.Methods 376 teachers were assessed with Symptom checklist (SCL-90),Life event scale (LES) and Coping questionnaire (CQ).Results The analysis showed non-native teachers score of SCL-90(150.74±44.57),somatization(1.69±0.58),obsessive-compulsive(1.84±0.58),depression(1.77±0.60),anxiety(1.63±0.55),hostility(1.68±0.61) and psychoticism(1.54±0.48) factor were higher than the native(P＜0.01).The concerned analyses showed non-native teachers score of SCL-90 was significantly positively related to LES score factor (P＜0.01).Teacher score of SCL-90 was significantly negatively related to settle problem factor of CQ(P＜0.01),and other factors of CQ was significantly positively.Conclusion The poor psychological health state and live emergency events of the non-native teachers should be pay more attention.

Objective To learn the psychological health state,life events and coping styles of the non-native policemen.Methods Symptom checklist (SCL-90),Life event scale (LES) and Coping questionnaire (CQ) was tested to native policemen(n=238) and non-native policeman(n=136).Results Score of SCL-90 (159.68±50.46) ,depression(1.79±0.62) ,photic anxiety(1.54±0.63) ,addition items(1.82±0.59) factors in non-native policemen were higher than that in the native policemen,and there was significant deference(P＜0.05).The concerned analyses showed non-native policemen score of SCL-90 was significantly positively related to LES total score and sub-scale factor (P＜0.01,P＜0.05).The non-native policemen score of SCL-90 was significantly negatively related to settle problem factor of CQ (P ＜ 0.01),and other factors of CQ was significantly positively(P ＜0.O1).Conclusion The poor psychological health state and live emergency events of the non-native policemen should be pay more attention.

The article reviewed the situation of warming kidney and strengthen spleen treatment for ulcerative colitis (UC) in recent 15 years from three aspects: Yang deficiency in spleen and kidney syndrome is one of the most important syndromes in UC; common prescriptions, medicine and efficacy of warming kidney and strengthening spleen treatment for treating UC; the mechanism of the treatment for UC is related to immunity enhancement, inhibition of gastrointestinal smooth muscle, promoting gastrointestinal function, antibiosis, improving plant nerve function, and release of enzymes. It also proposed the problems about warming kidney and strengthening spleen treatment for UC, and prospect for relevant problems.

Objective To investigate the status of clinical nursing teaching in the department of infection.Method To investigated the teachers and nursing students in the department of infection with a self-designed questionnaire.Results The evaluation from students to the teachers are:overall satisfaction score is(4?90±0?04),the lowest points are the advanced nursing of common diseases and the teaching attitude.While the evaluations from teachers are:overall satisfaction score is(4?45+0?04),the lowest are communication with patients and their families,conducting basic nursing operation and familiarity of common drugs.Conclusions To enhance teaching quality of clinical nursing teaching in the department of infection,it is efficient by improving the quality of teachers and their teaching methods,consolidating students’knowledge,and exercising their skills?

Objective To understand the relationship between the requirement and the consumption of the health management, and provide the theoretical basis for the developing of China health management. Methods It took the survey to understand the relationship among 152 medical staffs from the six counties surrounding with Shi Jiazhuang downtown. Results 85.5%of medical staffs always and almost accept health advisory and provide health guidance. There are not the direct relationship between the requirement and the consumption(x2 = 9.39,P＞0.05 ). Health advice and guidance are not translated into the concepts of investment on the health management and disease prevention (x2 = 1.69, P＞0.05 ). The medical staffs don't realize it is important to invest on the health. Conclusions Related industries should strengthen the training on the health management, publicize this profession, promote the development of health management services and improve the national health quality.[ Key words] Health promotion ; Needs assessment; Economics

【Objective】To observe the dynamic changes of flavonoids contents of Citrus grandis(L.)Osbeck var.tomentosa Hort..【Methods】The total flavonoid content was determined by spectral photometric analysis and naringin content by HPLC,and the fingerprints of Citrus grandis(L.)Osbeck var.tomentosa Hort.were studied by HPLC.【Results】With the increase of the fruit age,total flavonoid contents in the peel and the leaves of Citrus grandis(L.)Osbeck var.tomentosa Hort.decreased obviously.Fingerprints results showed that at the early fruit age the rhoifolin content in the peel increased with the fruit age and began to decrease 62 days later,while the rhoifolin content in the leaves showed no changes.【Conclusion】In terms of active components contents and economic value,the optimal collecting time for Citrus grandis(L.)Osbeck var.tomentosa Hort.is:young fruit,34 days,and immature fruit,55 days.

Objective To assess the influence of different processing technique on the quality of Exocarpium citri grandis.Methods The RP-HPLC method was adopted to determine the naringin content in Exocarpium citri grandis.The chromatographic conditions were: Kromasil ODS column(250 mm?4.6 mm),mobile phase being methanol-water-acetic acid(35∶61∶4),flow rate 1.0 mL/min,detection wavelength at 283nm and column temperature at 25 ℃.Results There were obvious differences in the naringin content of Exocarpium citri grandis which was processed by different methods: the naringin content processed by electro static drying method was much higher than that by bake drying method, natural drying method and vacuum drying method.Conclusion The electro static drying method is the best way for drying Exocarpium citri grandis.

Objective To explore the impact of the different antiepileptic drugs on cognitive function in patients with epilepsy.Methods There are 280 cases of patients with epilepsy from Department of Neurology in our hospital out-patient and hospitalization, while 32 cases are the normal control group. The patients were randomly divided into groups of topiramate, carbamazepine and sodium valproate group and topiramate plus valproate combined therapy group. Wechsler Memory Scale was used by the patients before and after treatment to assess cognitive function, and compared with the normal group. Results Carbamazepine monotherapy group and the valproate group were no significant difference in areas of cognitive function belong to the normal level; Topiramate monotherapy group cognitive function was significantly lower than normal, the joint drug group was the most of the lower level of cognitive function. Conclusion Carbamazepine and valproate monotherapy were applied had the minor cognitive impairment, combination therapy of epilepsy in patients had severe cognitive impairment.

OBJECTIVE To investigate theradiosensitization of combined inhibition of signal transducer and activator of transcription 3(STAT3) and hypoxia-inducible factor-1α(HIF-1α)on laryngeal squamous carcinoma of xenograft mice and its underlying mechanisms.METHODS Xenograft mice were divided into 5 groups randomly: control group(A), irradiation group(B), irradiation and AG490 group(C), irradiation and PX478 group(D), irradiation combined AG490 and PX478 group(E). The size of xenograft tumor was measured and calculated. The expression of Ki67 and HIF-1α was detected by immunohistochemical method. Western blot was used to detect the expression of PARP1.RESULTS The size of xenograft tumor in group E was smaller compared with that in group C and group D. There were significantly difference between them respectively (t=12.367,11.598,P=0.000). The expression of HIF-1α in group E was lower than that in group C and group D respectively, and there were significantly difference respectively(t=5.422, 3.000,P<0.05). Ki67 index in group E was lower compared with that in group C and group D respectively and there were significantly difference respectively (t=4.479, 4.352,P<0.05). The level of cleaved PARP-1 in group E was higher than that in group C and group D respectively and there were significantly difference respectively (t=5.507, 7.102,P<0.05). CONCLUSION Combined inhibition of STAT3 and HIF-1α can increase the radiosensitivity of human laryngeal squamous carcinoma in the xenograft mice.

Phyllanthus emblica L.and Terminalia chebula Retz.were the most common Tibetan medicines.The combination of Phyllanthus emblica L.,Terminalia chebula Retz.and Term inalia bellirica (Gaertn.) Roxb.was known as Triphala,which was the basis of the most frequently-used prescriptions.The present study summarized and made a further comparison between Phyllanthus emblica L.and Terminalia chebula Retz.over chemical constituents and pharmacological activities,which provided evidence for their clinical use and the basic theory.