1.Clinical characteristics of bacterial pneumonia with normal procalcitonin and C-reactive protein in infants and tod-dlers
Yujue ZHANG ; Lei ZHANG ; Lanping ZHANG
Journal of Clinical Pediatrics 2016;(2):101-104
Objective To study clinical characteristics of bacterial pneumonia with normal procalcitonin (PCT) and C-reactive protein (CRP) in infants and toddlers. Methods Retrospective analysis of clinical data of infants and toddlers with bacterial pneumonia was performed from January 1, 2013 to March 30, 2015. Of them, there were 92 cases with normal PCT and CRP (case groupe) and 95 cases with signiifcantly higher PCT and CRP (control group). Results The median age was 9.25 months in the case group, which was signiifcantly younger than that in the control group (16.55 months) (P<0.05). The median of the course before admission was 5.17 days in the case group, which was signiifcantly longer than that in the control group (3.5 days) (P<0.05). The proportions of fever, dyspnea, and hypoxemia were signiifcantly lower in the case group than those in the control group (P<0.05). Administration of antibiotics before admission was found in 83.69%of cases in the cases group, which was higher than that in the control group (P<0.05). The most common pathogens in the case group was Haemophilus inlfuenza, while Streptococcus pneumonia was the most common in the control group. Conclusion The possibility of bacterial infection cannot be ruled out in pneumonia with normal CRP and PCT in infants and toddlers.
2.Climate suitable rank distribution of artemisinin content of Artemisia annua in China.
Xiaobo ZHANG ; Lanping GUO ; Luqi HUANG
Acta Pharmaceutica Sinica 2011;46(4):472-8
At the urgent request of Artemisia annua (ART) planting, the paper gets artemisinin content (ARTC) of ART in China from literatures. The paper analyses the relationships between ARTC and ecological factors by statistical analytical methods. The paper also analyses the climate suitable rank distribution of ARTC in China by ArcGIS. The results display that first, ARTC is significantly different in China, that ART from the south regions ARTC is higher. Greatest north parts of China have not suitable climate for the growing of ART and the ARTC is lower than 0.2%, when ART grows above the 34th degree of northern latitude. ARTC is higher and ART grows well, when ART grows under the 34 degrees N and grows at the areas between 100 degrees E and 120 degrees E. Second, subtropical zone is the best suitable climate zone for the growing of ART. ART grows well and ARTC is higher than 0.5%, when ART grows in the subtropical zone. Third, temperature, sunshine duration and rainfall are the main ecological factors that affect the growth of ART and the accumulation of ARTC. That the year temperature between 13.9 degrees C and 22 degrees C, sunshine duration between 853 h and 1507 h, rainfall between 814 mm and 1518 mm, is the best climate for the accumulation of ARTC. Temperature between 13 degrees C and 29 degrees C, rainfall between 600 mm and 1300 mm is the best climate for the growth of ART. Fourth, in northwest of Guangxi, eastern of Sichuan, Guizhou and Yunnan provinces, south Chongqing and west Hunan Province, there are suitable climate for the growth of Artemisia and for the accumulating of ARTC. There are also some suitable climate areas for the growing of artemisia in the south of Hubei, Anhui and Jiangsu provinces.
3.Observation on the Treatment of Hepatitis E of Cholestasis Type with Rude Rhubarb Combined with Danshen Root
Renmin ZHANG ; Lanping WANG ; Shuhui LIU
International Journal of Traditional Chinese Medicine 2009;31(5):404-405
Objective To observe the therapeutic effect of rude Rhubarb combined with Danshen root treating Cholestatic hepatitis E. Methods 60 cases of cholestatic hepatitis E were randomly recurited into a treatment group and a control group, with 30 cases in each group. The control group was administrated with liver protection therapy, symptomatic treatment and supportive care. Based on therapies of the control group, the treatment group was taken with Rhubarb 3 g orally, twice daily, and intravenously dropped with Danshen root injection 20ml, once daily. Results The total effective rate of the treatment group and the control group was 93.3% and 66.7% respectively, showing significant differance(P<0.01 ). The value of TBil and DBil in the treatment group was statistically improved compared with the control group (P<0.01) . besides the hospitalized time of the treatment group was 46±9 days and hospitalization expense was 6630±1032 RMB, demonstrating a significant difference compared with the control group. Conclusion Rude Rhubarb combined with Danshen root can treat Cholestatic hepatitis E by improving the symptoms and reducing serum bilirubin level. Besides this method also shortens therapeutic time and reduces hospitalization costs.
4.The allergen analysis and nursing of abnormal rhinitis
Yuemei KAI ; Lanping SHI ; Yang ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2005;0(02):-
Objective To find out the common allergen of abnormal rhinitis in Shenzhen.Methods To take in process of allergopharma skin prick test(ASPT) for 855 dubitable patients with abnormal rhinitis to determine the main allergen.Results 578 patients in the 855 dubitable patients of abnormal rhinitis were positive(67.6%).These allergens were mostly inhalant.Among the 578 patients,51 cases were caused by single allergen;527 cases caused by more than two kinds of allergens;520 cases(90%) were positive in dermatophagoides pteronyssinus;488(84.4%) cases were positive in dermatophagoides farinae.Conclusion According to the common allergen of abnormal rhinitis in Shenzhen,and education to patients underwent ASPT can improve the accuracy of the test,lighten the symptom of abnormal rhinitis and raise the cure rate.
5.Effect of traditional Chinese medicine fumigation and intermediate frequency electrotherapy on cervical spondylosis: 69 cases report
Kezhi MIN ; Xiaohua LIU ; Lanping ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2000;6(2):76-77
观察现代熏蒸仪(中药熏蒸治疗)、中频电疗等治疗颈椎病的疗效。A、B、C三个治疗组共 69例患者。A组:中药熏蒸加中频电疗;B组:颈椎牵引加红外线;C组:中频电疗加红外线。比较A组和B组显效率:经统计学处理,0.01
6.Treatment of concave temporal area by fat granule auto-transplantation
Ping LIU ; Yi LIU ; Xiaoping ZHANG ; Limei MA ; Lanping ZHANG
Chinese Journal of Medical Aesthetics and Cosmetology 2009;15(1):17-19
Objective To summarize the clinical experience of fat granule injection for auto-trans-plantation in the treatment of concave temporal area. Methods The fat granule was extracted with injec-tor and injected into temporal area after washing and purging, but it might be necessany for patient to be injected extra 20 % fat autograft due to his absorptive effect. Results Satisfactory results were obtained in all patients. Transplantation was carried out one time in 139 cases, two times in 9 cases, and three times in 4 cases. 6 - 28 ml fat granule was injected in one site at each time. Conclusion Fat granule injec-tion for auto-transplantation is a safe and ideal method to treat concave temporal area.
7.Multi-factorial analytical study on real-time three-dimensional echocardiographic examination and image processing in children
Guozhen CHEN ; Kun SUN ; Lanping WU ; Yuqi ZHANG
Journal of Clinical Pediatrics 2010;(2):101-105
Objective To evaluate the importance of factors affecting efficiency of image display quality of realtime three-dimensional echocardiography (RT-3DE) and establish an optimized method for RT-3DE examination and image processing in children. Methods Based on corresponding cardiac acoustic characteristics in children, 87 healthy children (46 boys, 41 girls, mean 36.2 ± 44.2 months) were selected. Three aspects of seven factors were selected, including acquisition windows, gain, compress, post process, smoothing, frequency fusion and 3D vision for RT-3DE examination and analysis using orthogonal test design method. The principal effectiveness analysis of orthngonal test design method and its table L_(18)3~7 were used. The efficiency rate of 3D image display quality was used as the inspection index for orthogonal test. Results According to the average deviation orders of the seven factors, the maximal average deviation was gain. The aspects with maximal average deviation of each factor were at via-subcostal and via-apical acoustic windows, 90 of gain, 60 of compress, E of post process, 5 of smoothing, F3 of frequency fusion and A to B of 3D vision, respectively. Conclusions The optimized method for RT-3DE examination and image processing could be achieved by setting acquisition windows, gain, compress, post process, etc. It is helpful to promote clinical application of RT-3DE and benefits the design of multi-parameter presetting of ultrasound system to optimize RT-3DE examination in children.
8.Left Ventricular Twist in Patients with Atrial Septal Defect by Speckle Tracking Imaging
Mengxuan WANG ; Guozhen CHEN ; Yuqi ZHANG ; Lanping WU ; Chun ZHAO
Chinese Journal of Medical Imaging 2017;25(7):516-519,524
Purpose To evaluate features of the left ventricular twist in patients with atrial septal defect (ASD) using speckle tracking imaging (STI) in order to guide clinical application.Materials and Methods Fifty-eight patients with ASD confirmed by ardiac ultrasound in Shanghai Children's Medical Center from October 2015 to January 2016 were enrolled in this study as case group,which were further divided into group ASD-A with 30 cases and group ASD-B with 28 cases according to the volume of right ventricular.The volume of right ventricular was significantly increased in the group ASD-A,but the volume of right ventricular was not significantly increased in the group ASD-B.At the same time,30 normal children with matched age and sex were chosen as control group.The parameters of left ventricular twist motion in each group were measured and compared by using STI.Results In group ASD-A,The basal and apical part of 6 children rotated counterclockwise.Compared with those in the control group,the basal rotation angle and apical rotation angle of left ventricular in group ASD-A were significantly higher (P<0.01),and the peak twist and torison of left ventricular in group ASD-A were also higher (P<0.05).Compared with those in the control group,only the apical rotation angle in group ASD-B was higher (P<0.05),but the rest parameters of the left ventricular twist motion in group ASD-B were not statistically significantly higher (P>0.05).Conclusion The significant increase in the volume of right heart load in ASD impacts on the basal and apical rotation of left ventricular.
9.Study on the noninvasive estimation of pulmonary vascular resistance by color M-mode echocardiography assisted with computer
Yuqi ZHANG ; Baoying YE ; Kun SUN ; Sun CHEN ; Zhifang ZHANG ; Rong SHEN ; Lanping WU ; Wei GAO
Chinese Journal of Ultrasonography 2008;17(6):465-468
Objective To determine the feasibility and accuracy of velocity propagation within main pulmonary artery(VP)from color M-mode Doppler imaging using custom software on a personal computer for noninvasive estimation of PVR.Methods Color M-mode imaging of pulmonary flow was obtained and then transferred to computer,the velocity propagation of pulmonary flow was automatically obtained.Comparative studies among Doppler echocardiography,personal computer and cardiac catheterization for predicting PVR had been done in 20 children with congenital heart disease and 20 normal children.Results Velocity propagations of children with congenital heart disease were significant lower than those of normal children obtained by color Mmode echocardiography[(38.38±18.89)cm/s VS(80.34±15.65)cms,P<0.01),and correlated well with invasive PVR measurements(r=-0.69,P<0.01).The correlation and repeatability of VP obtained by the custom software were better than VP obtained by Doppler echocardiography(r=-0.78,P<0.01).A VP cutoff value obtained by the custom software of 35.910 had a sensitivity of 92.9% and a specificity of 100% to within pulmonary artery obtained by color M-mode echocardiography using custom software on a personal computer.
10.Evaluation of the structure of tricuspid valve with three dimensional echocardiography in hypoplastic right ventricle
Sun CHEN ; Kun SUN ; Shubao CHEN ; Yuqi ZHANG ; Zhifang ZHANG ; Lanping WU
Chinese Journal of Ultrasonography 2009;18(7):571-574
Objective To reveal the character of tricuspid valve in hypoplastic right ventricular heart syndrome (HPRVHS) using 3-dimensional echocardiography(3DE). Methods Twenty eight patients with HPRVHS were included in the study, and they were divided into two groups according the degree of tricuspid regurgitation. Eighteen normal children were included as the control. Volume of right ventricle(VRV), area of tricuspid annulus(TVA),proportion of the leaflets and the distance from tips of leaflets to the nearest papillary muscle were measured with 3DE. These data was standardized by body surface area. Results The volume of right ventricle in HPRVHS was significantly less than that in normal group. The area of tricuspid annulus was significantly correlated with volume of right ventricle(r = 0. 90, P < 0. 0001). In the tricuspid regurgitation group, the proportion of area of anterior leaflet to area of tricuspid annulus was significantly higher than non-regurgitation group and normal group(P <0. 0001). Respectively,the proportion of the area of posterior leaflet to the area of tricuspid annulus in regurgitation group was significantly less than normal and non-regurgitation group. The distance from tips of leaflets was significantly shorter in HPRVHS than in normal group. Furthermore, the distance from the tip of septal leaflet to the nearest papillary muscle was shorter in regurgitation group than non-regurgitation group ( P = 0. 0023). Conclusions 3DE could be applied for evaluating the pathologic change of tricuspid valve in congenital heart disease. In HPRVHS, hypoplastic of posterior leaflet and shortness of the cords of septal leaflet could be the cause of tricuspid regurgitation.