1.S-100 protein-positive langerhans cells and prognosis in patients with gastric carcinoma.
Hong Gee LYU ; Young Joo LEE ; Dong Kun KIM ; Min Chul LEE ; Young E PARK ; Chang Sig CHOI
Journal of the Korean Surgical Society 1992;42(2):165-170
No abstract available.
Humans
;
Langerhans Cells*
;
Prognosis*
2.Quantiative Study of Epidermal Langerhans Cell in Vitiligo.
Yoon Kee PARK ; Seung Kyung HANN
Korean Journal of Dermatology 1987;25(4):500-505
Report. about numeric change of LC between vitiliginous skin(VS) and adjacent normal appering skin (ANAS) are hard to find, Epidermal Langerhans Cell (LC) dersities in VS and ANAS were studied in 18 patient with generalized vitiligo. Adenosine triphosphatase(ATPase) stain was used to characterize LC. Epidermal LC densities were calculated by means of an eye piece reticule and expressed per mm. The results were as follows; 1. The was significant body site variation of LC densities in ANAS and the range of densities of LC per mm were from 668+165 to 1,241 _3 and the mean density of LC per mm was 944+258. 3. The LC densities of VS was similar to that of ANAS(p: not significant). In conclusion quantiative change of epidermal LC in vitiligo doesn't seem to have significant relation with pathogenesis of vitiligo.
Adenosine
;
Humans
;
Langerhans Cells
;
Skin
;
Vitiligo*
3.Systemic Cytotoxic Drugs Depletes Epidermal Langerhans Cells in Guinea Pigs.
Jin Wou KIM ; Jeung Kyu KIM ; Won HOUH
Annals of Dermatology 1989;1(1):10-15
No abstract available.
Animals
;
Guinea Pigs*
;
Guinea*
;
Langerhans Cells*
4.The effect of free oxygen radical scavengers on the expression of ATPase of mouse epidermal langerhans cells after UVB irradiation.
Seong Jin JEON ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1991;29(5):574-582
No abstract available.
Adenosine Triphosphatases*
;
Animals
;
Langerhans Cells*
;
Mice*
;
Oxygen*
5.The effect on the recovery of epidermal langerhans cells in C3H mice after single and fractionated exposure of ultraviolet B irradiation.
Sang Wahn KOO ; Seung Kyung HANN ; Yoon Kee PARK ; Moo Yon CHO
Korean Journal of Dermatology 1991;29(4):459-465
No abstract available.
Animals
;
Langerhans Cells*
;
Mice
;
Mice, Inbred C3H*
6.Langerhans cell histiocytosis of the mandible: two case reports and literature review
Dae Seok HWANG ; Jun Sang LEE ; Uk Kyu KIM ; Hae Ryoun PARK ; Mi Heon RYU ; Ji Hye LEE ; Yun Hoa JUNG ; Gyoo Cheon KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2019;45(3):167-172
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the proliferation of dendritic cells resulting in local or systemic symptoms. The clinical symptoms of patients with Langerhans cell histiocytosis depend on the site and the degree of involvement. This article describes two case histories of unifocal bony Langerhans cell histiocytosis with mandibular involvement and further discusses the appropriate management of such via a review of the literature.
Dendritic Cells
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Histiocytosis, Langerhans-Cell
;
Humans
;
Mandible
7.Recurrent Indeterminate Dendritic Cell Tumor of the Skin
Jin Woo JOO ; Taek CHUNG ; Yoon Ah CHO ; Sang Kyum KIM
Journal of Pathology and Translational Medicine 2018;52(4):243-247
Indeterminate dendritic cell tumor (IDCT) is a dendritic cell tumor that displays histologic features similar to those of Langerhans cells. The origin of the indeterminate cells may represent precursors of Langerhans cells or skin dendritic cells. IDCT is extremely rare, and tumor progression and predictive factors are not well known. Here, we report a case of a 61-year-old man who presented with a papule on his back and was finally diagnosed with IDCT based on histology and immunohistochemistry. The tumor recurred three months after surgical excision.
Dendritic Cells
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Humans
;
Immunohistochemistry
;
Langerhans Cells
;
Middle Aged
;
Recurrence
;
Skin
8.Intracranial Langerhans Cell Histiocytosis Presenting with Dysarthria and Gait Disturbance.
Chang Gon YOU ; Eun Jae LEE ; Ho Sung RYU ; Ji Hye HWANG ; Bo Mi KIM ; Sun Ju CHUNG
Journal of the Korean Neurological Association 2011;29(4):332-334
Langerhans cell histiocytosis (LCH) is a rare disease of the monocyte-macrophage system involving clonal proliferation of Langerhans cells. Central nervous system (CNS) involvement of LCH occurs in 10-57% of all LCH cases. This disease is known to present in two ways in the CNS: intracranial tumorous lesions or intracranial nontumorous lesions (neurodegeneration). We report here an LCH patient who developed gait disturbance and dysarthria due to neurodegenerative lesions associated with LCH.
Central Nervous System
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Dysarthria
;
Gait
;
Histiocytosis, Langerhans-Cell
;
Humans
;
Langerhans Cells
;
Rare Diseases
9.Isolated Thymic Langerhans Cell Histiocytosis.
Young Hee JUNG ; Seong Uk HWANG ; Ji Kyoung PARK ; Moo Young OH ; Soon Yong LEE
Korean Journal of Pediatric Hematology-Oncology 2004;11(1):74-79
Langerhans cell histiocytosis is a rare disease in which the Langerhans cells proliferate abnormally, like a cancer, and involve various tissues and organs, such as skin, bone, lung, lymph node, liver and spleen. Especially, in the younger age, it usually involves more organs and tissues, sometimes including the thymus. But isolated involvement of thymus is very rare. We report an 11-month-old-girl with an isolated thymic involvement of Langerhans cell histiocytosis with a brief review of related literatures.
Histiocytosis, Langerhans-Cell*
;
Langerhans Cells
;
Liver
;
Lung
;
Lymph Nodes
;
Rare Diseases
;
Skin
;
Spleen
;
Thymus Gland
10.Pathological Characteristics of 20 Cases of Langerhans Cell Histiocytosis and Specificity of Immunohistochemical Stain of Langerin (CD207).
Youngjoon RYU ; Hyunjoo LEE ; Sangho LEE ; Hoiseon JEONG ; Bongkyung SHIN ; Aeree KIM ; Hankyeom KIM ; Insun KIM
Korean Journal of Pathology 2009;43(2):113-119
BACKGROUND: Langerhans cell histiocytosis (LCH) is a well-known neoplastic disorder of Langerhans cells which has characteristic findings, however, LCH has not been adequately studied in Korea. METHODS: We analyzed the clinicopathologic features of 20 patients with LCH who were diagnosed between 1997 and 2006 at the Korea University Guro and Anam Hospitals. RESULTS: The M:F ratio was 3:1 and the age ranged from 2-60 years (mean, 23.8 years [4 in 1st decade, 6 in 2nd decade, 2 in 3rd decade, 5 in 4th decade and 3> or =40 years of age). The cases were classified as unifocal unisystemic in 13 patients, multifocal unisystemic in 4 patients, and multifocal multisystemic in 3 patients. The bone was the most commonly involved organ (14), followed by lymph node (5), lung (2), skin (2) and ureter (1). The Langerhans cells were immunohistochemically stained with Langerin, CD1a, S-100 protein, and CD68. Langerin and CD1a were specific for Langerhans cells. CONCLUSIONS: The distribution of the involved organs in patients with LCH was similar to the distribution in Western countries, but lymph node involvement was more frequent, whereas lung involvement was less common. Langerin is considered to be a specific marker for Langerhans cells.
Histiocytosis, Langerhans-Cell
;
Humans
;
Korea
;
Langerhans Cells
;
Lung
;
Lymph Nodes
;
S100 Proteins
;
Sensitivity and Specificity*
;
Skin
;
Ureter