1.Work Flow Design of Medical Equipment Preventive Maintenance
Chinese Medical Equipment Journal 1989;0(02):-
As a kind of initiative maintenance,preventive maintenance mainly aims at prolonging service life of medical equipment,extending their fault-free time and lowering the whole life expense.It is an important measure that preventive maintenance be strengthened in keeping the safe and highly efficient operation of medial equipment for maximum social and economic benefit.The work flow design of medical equipment preventive maintenance is introduced including the plan,execution and check,giving guidance to medical equipment preventive maintenance.[Chinese Medical Equipment Journal,2008,29(2):71,73]
2.Neuroprotective mechanism of erythropoietin on neonatal brain injury
International Journal of Pediatrics 2014;41(1):18-21
Brain injury is a significant cause leading to death of neonates with a considerable variety of complications.Up to now researches have found the neuroprotective actions of erythropoietin (EPO) originally identified as erythropoiesis on neonatal brain injury.EPO has been reported to induce a broad effect in the brain directed to protect and repair neurons damage which are likely to contribute to the improvement in long-term neurological functional outcomes.EPO may provide a new approach for promoting survival and growth in nerve cells and hold great promise for the future treatments of neonatal brain injury.EPO and EPO receptor distribute in defferent parts of brain in fetus and newborns.A fundamental mechanism of EPO-induced neuroprotection is its ability to inhibit apoptosis that EPO and EPO receptor have been shown to modulate three cellular signal transduction pathways.The other neuroprotection mechanisms of EPO-induced include anti-infammatory,neurotrophy,anti-oxidation,angiogenesis,promoting neurogenesis and anti-epilepsy.
3.The Experience of Zhang Yu-zhu Treating Bi-syndrome
Journal of Zhejiang Chinese Medical University 2014;(11):1280-1282
Objective]To summarize the clinical experience of Zhang Yu-zhu to treat Bi-Syndrome. [Methods] Summarized the academic view and clinical experience of Zhang yu-zhu to treat Bi-syndrome,including etiology and pathogenesis,therapeutic principle and the formulas of Zhang Yu-zhu. Summarize the compatibility and modified formulas,and proven cases attached. [Result] The cause of Bi-syndrome was divided into two types: one was external pathogen,which was caused by wind,cold and wet. The other was internal pathogen,including spleen and kidney deficiency,the unbalance of Ying qi and Wei qi and insecurity of the interstices. When diagnosing and treating Bi-syndrome ,he emphasized combining Chinese and western medicine and syndrome differentiation. [Conclusion]Zhang Yu-zhu's treatment of Bi-syndrome has evident effect.
4.CHANGES OF INSULIN-COUNTERACTING HORMONES DURING THE PERIOD OF KETOSIS IN TYPE I DIABETES
Chinese Journal of Endocrinology and Metabolism 1985;0(02):-
The concentration of plasma glucose, glucagon (GG), ACTH, cortisol (F), growth hormone (GH), prolactin (PRL), TSH, T3, T4, urinary catechola'mine (CA) and 3-methoxy-4-hydroxymandelic acid (VMA) were measured during the period of diabetic ketosis and 10 days after correction of ketosis in 10 male patients with type I diabetes (IDDM). It was showed that the levels of plasma GG, ACTH, F, and urinary CA were remarkably increased during the ketosis (P
5.The research on immune function in chinese heroin addicts.
Chinese Journal of Immunology 1985;0(03):-
In this article,We determined the basic immune function level in 30 herion addicts.The re-sults showed that herion had evidoutly injuring effect on fluid immunity and cellular imunity;The content of Serum IgA、IgG、IgM in heroin addicts was lower than that in control sespcidllythe IgA (P0.05);The cellularimmune function suffered notable damage:Compared wich controls,in heroin addicts T—lym-phocytes transormation rate,LTT、CD_3、CD_4 evidentlydecreased in heroin addicts (P
6.Protective Action of Tea Polyphenol on HepG2 Cells
China Pharmacy 2001;0(09):-
OBJECTIVE:To study the protective action of tea phlyphenol(TP)on HepG2cells injury and the possible mechanism.METHODS:Different concentrations of TP were added into HepG2cell culture fluid,which was then added with H 2 O 2 and CCl 4 to form2kinds of injury models,cell survival rate was figured out by detecting the optical density value and changes of AST activities were monitored.RESULTS:As compared with model group,different concentrations of TP increa_ sed the survival rate of the injured HepG2cells,and reduced the activities of AST(P
7.Expression of complement regulatory proteins C_1-INH and CD46 in nasal mucosa of allergic rhinitis rats
Academic Journal of Second Military Medical University 2000;0(10):-
Objective:To determine the expression of complement regulatory proteins(CRPs) C_1-INH,MCP(CD46) in the nasal mucosa of allergic rhinitis rats and to study the role of CRPs in the pathogenesis of allergic rhinitis.Methods: Nine healthy SD rats were sensitized and intranasally challenged with ovalbumin and Al(OH)_3(as supplement) to establish allergic rhinitis models and another 9 SD rats treated with saline were taken as control.The nasal mucosa in respiratory area of both groups was obtained.Then Western blotting was performed to investigate the expression levels of C_1-INH and CD46.Results: Western blotting showed that both C_1-INH and CD46 had been detected in rat nasal mucosa.Expression level of CD46 in the nasal mucosa of allergic rhinitis was significantly higher than that in control rats(P
8.Expression of E-selectin in colorectal neoplasm and its role in the metastasis of blood line
Journal of Chongqing Medical University 2007;0(07):-
Objective: To investigate the level of cell adhesion molecule E-selectin in colorectal neoplasm and its relations with metastasis in the blood line. Methods:E-selectin expression in colorectal carcinoma and normal colorectal tissue were detected with immunohisochemical technique. The change of shift ability of human colorectal neoplasm cell line was analyzed. Results: The expressing rate of E-selectin was 57.5%,obviously higher than 6.67% in the normal colorectal tissue(P
9.The therapeutic effects comparison between one and two hemoperfusion in treatment of chronic hepatitis with hyperbilirubinemia
Journal of Chongqing Medical University 1986;0(04):-
Objective:To investigate the clinical efficacy between one and two hemoperfusion in treatment of chronic hepatitis with hyperbilirubinemia.Methods:The clinical data of 68 chronic hepatitis patients with hyperbilirubinemia were reviewed restropectively.27 patients were treated with one hemoperfusion(HP1)and 41 patients were treated with two hemoperfusion(HP2).The liver function,prothrombin time activity,biochemical indicators before and after hemoperfusion in the two groups were compared and analyzed.Results:After two hemoperfusion treatment.,Compared with HP1,the levels of bilirubin and transaminase were decreased significantly(P0.05).Conclusions:Two hemoperfusion treatment can more effectively make bilirubin and transaminase removed from patients of chronic hepatitis with hyperbilirubinemia,so two hemoperfusion was safe and effective treatment for patients with hyperbilirubinemia.
10.Progress in CRELD1 gene on atrioventricular septal defect
International Journal of Pediatrics 2011;38(1):36-37,40
Congenital heart disease(CHD) is a series of birth defect that can actually or potentially impact heart function , occurring 4‰~ 12‰ of live birth. Atrioventricular septal defect (AVSD) is a frequently CHD affecting the atrioventricular valves and septa. AVSD refers to a clinical spectrum of defects ranging from a complete AVSD to cleft mitral valve. AVSD occurs most frequently in Trisomy 21 syndrome. Research shows that the development defect of endocardial cushion caused by heredity and environment during different period of heart development leads to all kinds of AVSD. CRELD1 is the first identified gene associated with morbidity of AVSD.The research on this gene has important significance to find out the pathogenesis of AVSD and provide better prevention and cure methods.