The authors report a case of Von hippel Lindau disease in a 20 years old patients with presenting signs: diminution of visual acuity, intracramial hypertension with a left cerebollar syndrome and existence of an retinal angioma on the right side and papilla oedema on the left side. A scanning examination revealed a cystic tumor with a solid little mass. Angiography showed a capillary nodus coressponding to the mass lesion, with feeding arteries coming from the anterio superior cerebellar artery. Removal of the cyst and the tumor was successful. Pathological examination: Hemangi oblastoma. Negative ultrasound examination of the kidney, pancreas.
Hippel-Lindau Disease ; Case Reports [Publication Type]

Objective To investigate the clinical application value and feasibility in the dynamic ECG moni-toring in the diagnosis on patients with sleep apnea syndrome complicated with arrhythmia .Methods A total of 80 cases of sleep apnea syndrome confirmed by polysomnography diagnosis were randomly divided into the two groups,40 cases in each group .The patients in the control group were received routine ECG monitoring ,the observa-tion group were underwent dynamic ECG monitoring ,the arrhythmia detection rate in the two groups were compared . Results The ventricular premature beat ,atrial premature beat,ventricular in patients with Beckoning tachycardia , paroxysmal ventricular tachycardia , paroxysmal atrial tachycardia , first degree atrioventricular block , second degree atrioventricular block,premature atrial arrhythmia with sinoatrial block detected in the control group were 6 cases, 7 cases,9 cases,6 cases,5 cases,1 cases,1 cases,5 cases,respectively.However,21 cases,19 cases,25 cases, 16 cases,19 cases,7 cases,8 cases,14 cases were confirmed in the observation group ,the positive detection rate in cardiac arrhythmias in the observation group were significantly higher than that in the control group (χ2 =19.700, 17.000,13.700,21.200,22.600,53.000,50.500,26.100,all P<0.05).Conclusion Dynamic electrocardiogram can improve the positive rate of arrhythmia ,and have important clinical value in the diagnosis and treatment of sleep apnea syndrome complicated with cardiac arrhythmias ,which is worthy of clinical application .

ObjectiveTo discuss the influence of health education to the pregnant women and their relatives on patients' satisfaction degree in grass-root hospitals. Methods200 pregnant women in our hospsital were divided into the experimental group and the control group, the experimental group was given systematic health education, while the control group only received the traditional reception. Then a survey was carried out in the two groups and the satisfaction degree of maternal women and their relatives with medical workers was compared. ResultsThe satisfaction degree Of maternal women and their relatives in the experimental group was higher than that of the control group. ConclusionsHealth education in gy-necology and obstetrics department and carrying out nursing with humanity can improve satisfaction degree of maternal women and their relatives to medical staffs.

Objective: To explore the pharmaceutical care mode for drug treatment and interactions through participating in the treatment of patients using cyclosporine A combined with anti-tuberculosis ( TB) drugs. Methods: The clinical questions were pro-posed and refined, the literature evidence was retrieved in the electronic databases, the questions were answered and the procedure and mode of pharmaceutical care for the similar clinical problems was established. Results:For the patients with cyclosporine A treatment, strong anti-TB drugs should be chosen to ensure the effectiveness and decrease the drug interactions, and the concentration monitoring of cyclosporine A should be paid more attention. Conclusion: Clinical pharmacists can implement the pharmaceutical care for the pa-tients with immunosuppression and TB infection through developing anti-TB regimen, avoiding the drug interactions, improving the drug safety and so on.

Objective To observe the clinical effects of estradiol valerate and drospirenone applying in missed abortion and curettage before and after operation.Methods 160 patients with missed abortion parallel curet-tage were chosen,who were randomly divided into the observation group and control group by the number table meth-od.Two groups of patients were oral misoprostol 400 g before uterine curettage 1 h,and then were treated with ultra-sonic curettage after filling the bladder and postoperative routine use of antibiotics for 3 D.3 D before the curettage, observation group were treated with oral estradiol valerate 4 mg for 3 D,2times a day..After curettage of the day, drospirenone orally was given for 1 tablet every night,used in conjunction a cycle for 3weeks.The control group before and after curettage were given without estradiol valerate and drospirenone.Operation time,bleeding volume,postopera-tive bleeding time and bleeding volume,the time of the first menstrual cycle,endometrial repair and postoperative complications were observed in the two groups.Results In the control group,operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time,endometrial thickness,postoperative complication rate were (6.05 ±0.49)min,(50.88 ±9.18)mL,(36.51 ±1.95)d,(4.08 ±0.56)mm and 15.0%;the data of the observation group were (4.46 ±0.45)min,(35.63 ±8.24)mL,of (29.28 ±1.57)d,(6.11 ±0.76)mm and 3.8%.The operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time, endometrial thickness,postoperative complication rate differences of the two groups were statistically significant(t =-11.264,-16.643,-24.93,19.151,χ2 =5.959,all P <0.05).Conclusion Giving estradiol valerate and flexor buspirone before and after missed abortion and curettage,can effectively improve the short -term and long -term complications of uterine curettage,and improve the clinical efficacy of dilatation and curettage.

Objective:To observe the therapeutic effects of treating traumatic gonarthromeningitis with acupuncture combined Chinese herbs.Methods:Seventy Patients were randomly divided into two groups,with 35 cases in each group.The treatment group was treated with Chinese herbal medicine,acupuncture and cupping therapy.The control group was treated with Diclofenac Sodium Tablets,Corydalis Analgesic Tablets and Vitamin C Tablets.Results:The total effective rate of the treatment group was higher than that of the control group.There was a statistically significant difference between the two groups(P＜0.05).Conclusion:The combined therapy with acupuncture and Chinese herbal medicine has a remarkable therapeutic efrect on treating traumatic gonarthromeningitis.

Objective To analyze the clinical curative effect of retroperitoneoscopy combined with inguen small incision surgery in treatment of urothelium carcinoma.Methods Ninety-eight urothelium carcinoma patients were divided into observation group (56 cases) and control group (42 cases) according to the surgery method.The patients in observation group were treated with retroperitoneoscopy combined with inguen small incision surgery,and the patients in control group were treated with open surgery.The operation time,intraoperative bleeding volume,postoperative drainage volume,postoperative gastrointestinal function recovery time,postoperative ambulation time,drainage tube removal time,hospitalization time,incision fat liquefaction,incision hernia,incision prolapse,incision pain and discomfort,postoperative analgesia,postoperative 3 months incision satisfaction and postoperative 36 months tumor recurrence were observed.Results The operation time,intraoperative bleeding volume,postoperative gastrointestinal function recovery time,postoperative ambulation time and hospitalization time in observation group were significantly lower than those in control group:(135.23 ±32.18) min vs.(177.58 ±57.29) min,(119.33 ±35.02) ml vs.(161.29 ± 72.06) ml,(2.03 ± 0.73) d vs.(2.79 ± 0.79) d,(20.68 ± 9.75) h vs.(32.41 ± 11.12) h,(8.51 ± 0.93) d vs.(9.81 ± 2.21) d,and there were statistical differences (P ＜ 0.05 or ＜ 0.01).There were no statistical differences in postoperative drainage volume and drainage tube removal time between 2 groups (P ＞ 0.05).The rates of incision fat liquefaction,incision hernia,incision prolapse,incision pain and discomfort and postoperative analgesia in observation group were significantly lower than those in control group:1.79％ (1/56) vs.26.19％ (11/42),0 vs.11.90％ (5/42),0 vs.7.14％ (3/42),1.79％ (1/56) vs.11.90％ (5/42),1.79％ (1/56)vs.11.90％ (5/42),the rate of postoperative 3 months incision satisfaction in observation group (92.86％,52/56) was significantly higher than that in control group (78.57％,33/42),and there were statistical differences (P ＜ 0.01 or ＜ 0.05).The rate of tumor recurrence in observation group (14.29％,8/56) was significantly lower than that in control group (47.62％,20/42),and there was statistical difference (P ＜ 0.01).Conclusions Retroperitoneoscopy combined with inguen small incision surgery in treatment of urothelium carcinoma can significantly reduce the patients' treatment and recovery time,improve the beauty of incision and patients' satisfaction degree,and reduce the postoperative tumor recurrence rate.

The effective therapy of limited stage-small cell lung cancer( LS-SCLC) is combined chemotherapy and thoracic radiotherapy(TRT). Early thoracic irradiation is better than later one. Start of any treatment and end of radiotherapy less than 30 days is associated with improved survival in LS-SCLC patients. Concurrent chemoradiotherapy results in longer survival time than sequential and alternating chemoradiotherapy. There are no clear answers on optimal irradiation dose. Hyperfractinated irradiation may have therapeutic benefit compared with conventional irradiation.

Parenteral nutrition (PN) is one of the important measures to cure premature babies and critically ill infants.In recent years,with the improvement of rescue techniques in the perinatal period,a growing number of preterm infants alive,very low birth weight and low birth weight infants gradually become an important part of the neonatal disease.The gastrointestinal development of these premature babies are not mature or combined with other diseases,in a long period of time after birth need partial or complete PN support.Due to the use of PN,provides the children with survival and greatly reduce the case fatality rate,but the cause of parenteral nutrition associated cholestasis would become one of the main complications of premature infants,seriously affect the patient's quality of life.In this paper,the treatment of premature parenteral nutrition associated cholestasis status is summarized.

Three active components were isolated from the metabolite of Pseudomonas sp.20~(#)-5 by using organic solvent extraction,silica gel column chromatogram and C-18 reverse phase chromatogram in HPLC.Two of them were identified as phenazine-1-carboxylic acid and 3-n-heptyl-3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-dione respectively.