The authors report a case of Von hippel Lindau disease in a 20 years old patients with presenting signs: diminution of visual acuity, intracramial hypertension with a left cerebollar syndrome and existence of an retinal angioma on the right side and papilla oedema on the left side. A scanning examination revealed a cystic tumor with a solid little mass. Angiography showed a capillary nodus coressponding to the mass lesion, with feeding arteries coming from the anterio superior cerebellar artery. Removal of the cyst and the tumor was successful. Pathological examination: Hemangi oblastoma. Negative ultrasound examination of the kidney, pancreas.
Hippel-Lindau Disease ; Case Reports [Publication Type]

Anal Canal ; surgery ; Humans ; Postoperative Complications ; Rectal Neoplasms ; surgery

Objective To observe the clinical effects of estradiol valerate and drospirenone applying in missed abortion and curettage before and after operation.Methods 160 patients with missed abortion parallel curet-tage were chosen,who were randomly divided into the observation group and control group by the number table meth-od.Two groups of patients were oral misoprostol 400 g before uterine curettage 1 h,and then were treated with ultra-sonic curettage after filling the bladder and postoperative routine use of antibiotics for 3 D.3 D before the curettage, observation group were treated with oral estradiol valerate 4 mg for 3 D,2times a day..After curettage of the day, drospirenone orally was given for 1 tablet every night,used in conjunction a cycle for 3weeks.The control group before and after curettage were given without estradiol valerate and drospirenone.Operation time,bleeding volume,postopera-tive bleeding time and bleeding volume,the time of the first menstrual cycle,endometrial repair and postoperative complications were observed in the two groups.Results In the control group,operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time,endometrial thickness,postoperative complication rate were (6.05 ±0.49)min,(50.88 ±9.18)mL,(36.51 ±1.95)d,(4.08 ±0.56)mm and 15.0%;the data of the observation group were (4.46 ±0.45)min,(35.63 ±8.24)mL,of (29.28 ±1.57)d,(6.11 ±0.76)mm and 3.8%.The operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time, endometrial thickness,postoperative complication rate differences of the two groups were statistically significant(t =-11.264,-16.643,-24.93,19.151,χ2 =5.959,all P <0.05).Conclusion Giving estradiol valerate and flexor buspirone before and after missed abortion and curettage,can effectively improve the short -term and long -term complications of uterine curettage,and improve the clinical efficacy of dilatation and curettage.

As a connecting bridge between innate immunity and specific immunity,the Toll-like receptors (TLRs) play a significant role in inflammation,cellular signal transduction,and cell apoptosis.TLRs are also essential factors participating in immune regulation and immune escape in the pathogenesis and development of malignant tumors.A large number of clinical and experimental research have shown that the abnormal expression of TLRs can be detected in adenocarcinoma,such as lung cancer,breast cancer and colon caner.In recent years,the relationship between gynecologic malignant tumor and TLRs has received great interest.This article will review and summarize research progress of TLRs in ovarian cancer,cervical cancer,and endometrial neoplasia.

Objective To investigate the clinical effectiveness of peripherally inserted central catheters(PICC) and peripheral intravenous catheters(PIV) in tumor chemotherapy. Methods A total of 180 patients with intravenous chemotherapy were randomly divided into two groups. 108 patients in the PICC group, 72 patients in the PIV group. The holding time and complications were observed and compared. Results The rate of complication in the PICC group were much lower than the PIV group, however was much longer than the PIV group in holding time. But there was no statistical difference in the positive culture rate of bacteria of two groups. Conclusions It is very safe to use PICC which can reduce the rate of complication of catheters and venipuncture times and is worthy of spreading in practice.

It is a popular practice for Chinas academia to regard SCI(Science Citation Index)and its IF(Impact Factor)as fundamental indexes for research competency evaluatiop.This article however holds that SCI and IF are but quantitative measurements for evaluating periodicals,and whether it is scientific to evaluate research results with such indexes as they are remains to be jusfified.It also suggests that practitioners in research organizations fully comprehend the meaning of SCI and IF,and use them correctly,so as to guide researchers to contribute their works to proper publishers.

OBJECTIVE:To investigate effect of valsanan on heart function in patients with chronic heart failure(CHF).METHODS:A total of 113 CHF patients were assigned into 2 groups.Both group received routine therapy and observation group were additionally treated with valsanan.Clinical efficacies of 2 groups before and after treatment were observed in terms of cardiac function classification,LVIDD,SV,CO,LVEF and 6 min walking test.RESULTS:In observation group,the incidence of improvement of the cardiac function was higher than in control group(P

Sixty patients with malignant stenosis, esophagus and anastomotic stoma fistula were selected from Jiangsu General Hospital of Armed Police Forces between January 1995 and June 2008, including 46 males and 14 females, aged 36-77 years. Following pathologic diagnosis, 50 patients had squamous cell carcinoma, 8 had adenocarcinoma, and 2 had adeno-squamous carcinoma. Of 60 patients, 33 had esophageal carcinoma stenosis and esophagus-gastric cardia carcinoma stenosis, 20 had esophageal carcinoma stenosis combined with fistula, 7 had esophageal-stomach anastomosis combined with thoracic cavity fistula; in addition, there were 22 cases of first onset of fistula and 5 of multiple fistula. All patients were treated by esophagus memory Ni-Ti alloy coated stent implantation. Of 58 patients with successful implantation, 21 developed stent blockage due to dysphagia, and were alleviated after foreign body removal; 3 developed stent dislocation (removal and re-implanted); 7 developed restenosis due to tumor tissue ingrowth 3 months after implantation. Of 5 patients with multiple fistula, 3 were re-implanted to form invagination of 2 stents, which succeeded in blocking the fistula. Of 33 patients with esophageal carcinoma stenosis and esophagus-gastric cardia carcinoma stenosis, 26 underwent radiotherapy with or without chemotherapy (mean survival time: 24 months). Twenty patients with esophageal carcinoma stenosis combined with fistula survived for 6 months averagely. Seven patients with esophageal-stomach anastomosis combined with thoracic cavity fistula survived for 3 months averagely. Of 60 patients, 42 felt retrosternal pain, and 2 patients’ stents were extracted due to severe pain; 20 patients developed esophageal reflux. No bleeding, perforation or septicemia occurred. The results indicate that memory Ni-Ti alloy stent is effective in treating malignant stenosis, esophagus and anastomotic stoma fistula, showing good biocompatibility.

Objective To study the applied value of unified image enhancement(IE) and tissue equalization(TE) that the two kinds post-processing functions in the diagnosis of patella fracture. Methods The images of knee joint anterior-posterior position of fifty patella fracture patients were taken. The acquired images were processed with IE and TE, and then the im- ages were divided into pre-treatment group and post-treatment group. Results The post-treatment group of patella imaging have markedly improved, and the statistics analysis have significance difference(P

Recent studies have showed that adrenal insufficiency are common in some status of critically ill children,like systemic inflammatory response syndrome,sepsis,shock,et al.The frequency of adrenal crisis was also higher than expectation.The currrent glucocorticoid replacement therapies are inclined to lower dose [ hydrocortisone 20 ～ 25 mg/( m2· d) ].The adrenal function could be evaluated with the free cortisol index and calculated free cortisol.A new method,temperature-controlled centrifugal ultrafiltration with chemiluminescence immunoassay,has been used to detect the free cotisol,which has improved the clinical practicality.