As one of the "three key virtues" of Confucianism,wisdom played a significant role in the thousands of years of traditional Chinese culture.The nature of medical skills is humanity.However,as the great development of medical technology in modern society,tension and conflicts also arise in the current physician-patient relationship.Under this circumstance,this paper explores the origin of Confucian wisdom and its connection with modern physician-patient relationship,and comes up with suggestions for constructing a modern harmonious physician-patient relationship.