1.Autologous dendritic cell transplantation as an adjuvant treatment in pleomorphic lung carcinoma.
Chung Francisco S. ; Tan-Liu Nelia S. ; Ladrera Guia Imelda Elena R. ; Habaluyas Ramoncito S. ; Yuson Ernesto DJ. ; Danguilan Joselito J. ; Bernal Samuel D. ; Rubio Juanito A. ; Barzaga Maria Teresa A.
Acta Medica Philippina 2013;47(4):72-75
We embarked on autologous dendric cells (DC) transplantation as an adjuvant therapy with chemotherapy in a pleomorphic lung carcinoma patient. DC were isolated from PBMC and primed with the autologous tumor lysate. No adverse event was noted in DC transplantation. DC administration also correlated with immunomodulation, as evidenced by an approximately 5-fold increase in serum interferon gamma after 2 months. The utility of autologous DC transplantation may offer a clinical benefit with virtually no adverse event.
Human ; Male ; Adult ; Interferon-gamma ; Leukocytes, Mononuclear ; Immunomodulation ; Neoplasms ; Transplantation, Autologous ; Combined Modality Therapy
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