OBJECTIVE:To evaluate the cost-effectiveness of imported and domestic cefoperazone/sulbactam sodium in treating lower respiratory infection.METHODS:60patients with lower respiratory infections were ascribed to receive im-ported or domestic cefoperazone/sulbactam sodium(2∶1)respectively,the curative effects of the drugs were monitored and evaluated by cost-effectiveness analysis.RESULTS:The costs of the two groups were3164.00yuan and828.80yuan,re-spectively(P0.05),respectively;The cost-effectiveness ratios were37.98and10.36,respectively;And the incremental cost-effectiveness ratio of the imported group vs.the domestic group was707.64.CONCLUSION:Domestic cefoperazone/sulbactam sodium is a more economical choice.

OBJECTIVE: To introduce the current application of drug eluting stents in clinical practice, and investigate the advanced study of sirolimus and paclitaxel eluting stents. DATA SOURCES: An online research of Medline database was undertaken to identify the articles about drug eluting stents published between January 1996 and December 2006, with the keywords of "drug eluting stents, sirolimus eluting stents, paclitaxel-eluting stents", and language was limited to English; Meanwhile, the Chinese articles were retrieved in the Wanfang database from January 2000 to December 2006 by inputting the keywords "drug eluting stents, sirolimus eluting stents, paclitaxel eluting stents". STUDY SELECTION: Over 200 literatures were screened out, and those related with the clinical application of drug eluting stents were collected, subjecting as patients. Randomized or nonrandomized study and control or uncontrol group were all involved. Randomized control large sampling study was preferred for the similar content. Finally 30 articles were included. DATA EXTRACTION: Among 30 selected articles, 5 papers briefly introduced the characteristics of drug eluting stents, 10 papers discussed the mechanism of preventing and treating restenosis by sirolimus eluting stents and paclitaxel eluting stents, 15 papers referred to the clinical application of eluting stents. DATA SYNTHESIS: Drug eluting stent can inhibit the inflammatory reaction and cellular proliferation, delay the vascular endothelization, distinctly reduce the in-stent restenosis after percutaneous coronary intervention, and obviously develop the indication of Percutaneous intervention by releasing one or several bioactive substance to blood and surrounding tissues. Currently it is conformed in randomized control clinical trials that sirolimus eluting stents and paclitaxel eluting stents can decrease in-stent restenosis in patients with simple coronary artery stenosis, but the application on those with complex bifurcation affection and acute myocardial infarction is unknown. In addition, the high cost and in-stent thrombogenesis are also in debates. CONCLUSION: Drug eluting stents will be widely applied to reduce the in-stent restenosis and cardiovascular adverse events due to the advancement of interventional technique, modification of interventional instrument and appearance of anti-proliferation drug, which is more specific and lower poisonous and side effects.

This paper deals with a preliminary experience of the selective external carotid angiography by retrocatheterism via the superficial temporal artery in 6 cases.The method and technique were completely described.The external carotid angiography in different ways was discusse.Authors believe that the external carotid angiography by retrocatherism via the superficial temporal artery is a simple and reliable method, the image being very clear and complicatins rare.The method is worth using in oral maxillofacial surgery.

In this paper,We report the treatment of ten cases of cavernous hemangioma of parotid gland in infancy.It is suggested that a surgical operation should be performed as early as pos- sible.The difficulties of the operation and the points for attention are discussed as well.

The paper reports 214 cases of the bening parotid tumors which were treated by the parotidectomy of preserving the facial nerves during 1970-1987. Superficial parotidectomy was done in 30 cases, and total parotidectomy in 184 cases. The result of the follow-up survey of 176 cases was gained. No permanent facial paralysis and recurrence occured after the parotidetomy.

This paper reports the experience of free autogenous tibial periosteum grafting for 9 pa- tients with cleft palate.No dehiscence appeared after the operation and the wound healed up well.The upper jaw occlusal film showed hyperosteogeny in two weeks after the operation. The surgical probabiity,surgical method and points for attention have been discussed.

CEA concentration in human serum, whole salive and parotid salive were determined by using radioimmunty analysis on the people who have been assayed and analysed.30 of them were normal, 9 had parotid disease but no tumor, 13 with benign parotid tumors and 16 with malignant parotid tumors.The integratve analysis were made by combining clinical features with pathological diagnoses.The results show that, in normal persons, CEA concentration in serum is

In this report,we present the measurement and observation of the main branches of ex- ternal carotid artery of 60 adults' head-neck specimens.In order to catheterize via superficial temporal artery (angiography or chemotherapy) and do arterial anastomosis,we meas- ured the angle between superficial temporal artery and external carotid artery as well as that between superficial temporal srtery and temporal bone malar process.We also measured the intimal girth of superflcial temporal artery.and calculated its internal diameter.The report is intended to offer a reference for clinical practice and Chinese constitution investigation.

A sclerosing stromal tumor of the ovary (SST) is an extremely rare benign solid ovarian tumor,which is derived from the ovarian stroma and is a distinct subtype of sex cord-stromal tumor.It can not just be diagnosed accurately by routine preoperative physic-chemical examinations and postoperative immunohistochemical examinations.Recently,the application of fine needle aspiration cytology (FNAC) has improved diagnostic accuracy,but the final diagnosis relies on pathological examination.Compared with the traditional way of oophorectomy and salpingo-oophorectomy,the laparoscopic removal of SST will improve future success of pregancy.Besides,SST is an obvious endemic problem.Therefore,an increase in preoperative diagnosis rate of SST can avoid casual extension of resection during surgery and protect patients' fertility.

Objective To explore the efficacy of different modes of fluid resuscitation (early or delayed use of norepinephrine) on lung injury of septic shock rat induced by LPS.Methods A total of 60 male Wistar rats were randomly (random number) divided into 4 groups:the normal control group (group A,n =15),septic shock control group (group B,n =15),conventional fluid resuscitation group (group C,n =15),fluid resuscitation with early using of norepinephrine group (group D,n =15).All rats were mechanically ventilated with the same parameters.In the group C,norepinephrine was used 30 min after fluid resuscitation.In the group D,norepinephrine was used at the beginning of fluid resuscitation.Vital signs,volume of fluid infused and dosage of norepinephrine were recorded.Rats were sacrificed 2 h later and blood samples were collected for blood gas analysis.The lung tissues and BALF were collected.Pathological changes of the lung tissues were observed under light microscope.The levels of MPO,SOD and MDA were detected.The levels of IL-6,IL-8 and TNF-α in BALF and in serum were detected by using ELISA.Results Compared with group C,the mean volume of fluid infusion to achieve target blood pressure was decreased,oxygenation index was improved and the level of blood lactic acid were decreased in group D (P ＜ 0.05).HE staining indicated that inflammatory cells were decreased,pulmonary edema and alveolar walls hyperemia were alleviated in group D in comparison with group C.Inflammatory cytokines (IL-6,IL-8 and TNF-α) in BALF and in serum were significantly decreased in group D compared with group C (P ＜0.05).Levels of MPO were decreased in group D compared with group B and group C.However,early using of norepinephrine had limited effect on the levels of SOD and MDA.Conclusions The current study demonstrated that fluid resuscitation with early use of norepinephrine exhibited a protective effect on lung injuries induced by LPS.