ObjectiveTo investigate the effect of nitric oxide(NO) in preventing postoperative adhesion formation in rats .MethodsForty rats were randomly assigned to 2 different treatment groups.All animal models of postoperative adhesion formation were made in a standard manner. 0.9% NaCl and L-arginine were administered into intraperitoneal cavity before closure and during 3 consecutive days after surgery. On the 3 rd postoperative day,blood was collected to evaluate NO levels and the inserted abdominal walls were removed to assess pathology in some rats.On the 14 th postoperative day,the remaining rats were sacrificed by ether overdose before relaparotomy,and the extent of adhesion formation were assessed.ResultsMore severe adhesions developed in 0.9% NaCl control group(mean score of adhesions 3.7?0.7) than L-arginine group(mean score of adhesions 0.9?1.1)( P

Objective To analyze the growth and development condition of the children with cerebral palsy,and to investigate the influence of puberty on their adult height.Methods 56 children with cerebral palsy were selected as research subjects.34 healthy children were selected as control group.Their height and weight were measured,the development condition of their sexual character was checked,and then standard deviation of height and weight,height age and bone age were calculated,adult height and target height were predicted and analyzed.Results The standard deviation of height and weight in cerebral palsy group was (-1.29 ± 1.39) and (-0.77 ±1.20) respectively,which was lower than that of the normal control group[(0.40 ±0.95),(0.38 ± 1.01)] (t =-6.270,-4.6 7 6,all P ＜ 0.0 5).In preadolescent cerebral palsy group,the chronobiological age was bigger than their height age and bone age,the difference was significant (t =6.381,7.939,all P ＜ 0.05),but there was no significant difference between height age and bone age (P ＞ 0.05),there existed no significant difference between predicted adult height and target height(P ＞ 0.05).In adolescem cerebral palsy group,the chronobiological age and bone age were larger than their height age,which indicated significant difference (t =3.438,-3.759,all P ＜ 0.05),but there was no significant difference between the chronobiological age and bone age (P ＞ 0.05),the predicted adult height was lower than target height,the difference was significant (t =-5.204,P ＜ 0.05).Conclusion The growth and development of children with cerebral palsy would usually fall behind the normal children,but showed similarity in terms of starting age and process of puberty.After puberty,their bone age would increase dramatically,their predicted adult height would fall behind target height distinctly.

Objective:To understand the fever rate, disease distribution, fever degree and fever related factors of the patients in the same period of oral and maxillofacial tumor repair and reconstruction.Method:A retrospective analysis was performed on 153 patients who underwent radical treatment of oral and maxillofacial tumors from January 2018 to December 2018 in the affiliated stomatological hospital of sun yat-sen university. The patients were divided into fever group and non fever group, and their fever influencing factors were analyzed.Result:Among the 153 patients, 97 (63.40%) had fever symptoms.It’s mainly moderate fever. The incidence of fever was the highest in gingival cancer and oropharyngeal cancer.The results of univariate analysis showed that there were statistically significant differences in serum albumin, tracheotomy and infection between the two groups ( χ2= 7.74, 7.48, 8.58, P<0.01 or 0.05).Logistic multivariate regression analysis showed that infection and tracheotomy were independent influencing factors for postoperative fever in patients with oral and maxillofacial tumor repair and reconstruction (or = 4.74, 2.47, P < 0.05). Conclusion:Patients with oral and maxillofacial tumors undergoing radical treatment and simultaneous repair and reconstruction are more likely to have fever after surgery. Tracheotomy patients and patients with infection need to be paid more attention. They need to be strengthened tracheotomy care and actively prevent infection, so as to reduce the postoperative fever rate, and make the patients with oral malignant tumors repaired and reconstructed at the same time go through the perioperative period smoothly.

Objective: To understand the incidence and influencing factors of postoperative constipation in patients with malignant tumors who undergo oral and maxillofacial surgery and construct a constipation risk prediction model to provide a reference for the prevention and treatment of postoperative constipation. Methods: The data of 191 patients who underwent oral and maxillofacial malignant tumor surgery at the Affiliated Stomatological Hospital of Sun Yat sen University from June 2019 to June 2020 were analyzed retrospectively. The independent influencing factors were selected via univariate analysis and logistic multivariate regression analysis, a risk prediction nomogram was established, and the prediction model was evaluated by the area under the ROC curve. Both internal and external use the C index to verify the accuracy of the model. Results : Among 191 patients, 52 (27.23%) had postoperative constipation. Univariate analysis showed that a preoperative secret history of defecation, total energy intake, tracheotomy, smoking, drinking, operation duration, bleeding volume, bed time, eating homogenate diet, sex, surgical repair method, use of probiotics, T-stage of cancer and food intake may be the influencing factors of postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). Multivariate analysis showed that repair method, bed time and sex were independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors (P<0.05). The repair method was a fibular myocutaneous flap with a long bed time, and male patients were prone to constipation after surgery. The c-index values in the training group and the verification group were 0.882 and 0.953, respectively. The area under the ROC curve of the training group was 0.909 (95%CI: 0.850-0.968), and the area under the ROC curve of the verification group was 0.893 (95%CI: 0.787-0.999). The nomogram showed good discrimination ability. Conclusion The repair method, bed time and sex are independent risk factors for postoperative constipation in patients with oral and maxillofacial malignant tumors. The risk prediction model has good discrimination ability.