Objective To evaluate the clearance effect of hemodiafihration(HDF) and hemopeffusion combined with hemodialysis( HP + HD) on serum calcium,phosphorus and parathyroid hormone in patients with uremia.Methods Fifty-eight uremia patients treated with maintenance hemodialysis in our hospital from May 2009 to October 2010 were randomly divided into two groups:HDF group (n =29)and HP + HD group (n =29).Patients in HP + HD group underwent HD conventional treatment 5 times and HP + HD.treatment once every two weeks,while those in HDF group underwent HD treatment 5 times and HDF treatment once every two weeks.All subjects were treated for 12 weeks.Serum calcium,phosphorus and parathyroid hormone were detected and analyzed before and after the treatment.Results After therapy,the serum calcium ( [ 2.41 ± 0.32 ] mmol/L v.s.[ 2.22 ± 0.35 ] mmol/L,t =5.47,P ＜ 0.01 ),phosphorus( [ 1.98 ± 0.34 ] mmol/L v.s.[ 1.70 ± 0.31 ] mmol/L,t=8.13,P ＜0.01)and parathyroid hormone( [645.19 ± 184.52] ng/L v.s.[296.79 ± 103.54]ng/L,t =6.54,P ＜ 0.01 ) levels of HP + HD group decreased significantly.Similarly,the serum calcium ( [ 2.43 ± 0.33 ] mmol/ L v.s.[ 2.32 ± 0.37] mmol/L,t =6.72,P ＜ 0.01 ),phosphorus ( [ 1.97 ± 0.36 ] mmol/L v.s.[ 1.83 ± 0.35 ] mmol/L,t =6.47,P ＜ 0.01 ) and parathyroid hormone ( [ 639.47 ± 208.73 ] ng/L v.s.[ 409.91 ± 152.72 ] ng/L,t =5.27,P ＜ 0.01 ) levels of HDF group also decreased significantly.Comparison of the two blood purification methods indicated that the clearance effect of HP + HD on serum calcium,phosphorus and parathyroid hormone was significantly better than HDF( t =4.24 and t =7.24,P ＜ 0.01 ).Conclusion Both HDF and HD + HP could clear serum calcium,phosphorus and parathyroid hormone effectively,while the clearance effect of HD +HP is better than HDF.

OBJECTIVE:To prepare compound rifampicin auristilla and to establish a method for its quality control.METHODS:The content of rifampicin was determined by HPLC and the sample was stored under the temperature of(6?2)℃for6months.RESULTS:The linear range for rifampicin was6～60?g/ml,the average recovery was100.33%(RSD=1.23%).The appearance,pH value and contents of the preparation were in conformity with the requirements after storage for6months.CONCLUSION:This preparation method of compound rifampicin auristilla is simple and cheap,and its quality is controllable.

OBJECTIVE:To optimize the preparation technology of Baicalein sustained release microspheres.METHODS:The microspheres containing baicalein were prepared using solvent evaporation technique.Multiple linear regression equation and quadratic polynomial equation were fitted respectively with the mass ratio of the matrix materials,sodium dodecyl sulfate(SDS)concentration in water phase and drug content as independent variables,and with the accumulative drug release percentage at 2,12 and 24 h(Y1,Y2,Y3)as dependent variables.RESULTS:The baicalein sustained release microspheres prepared in accordance with the above technology were spherical and even.The optimized technical conditions were as follows:the drug content was 25%;the ratio of the matrix materials was 3.5;SDS concentration was 0.08%;Y1,Y2 and Y3 were 21.05%,55.70% and 87.75%,respectively.All the three equations fitted using quadratic polynomial equations achieved good fitting results.CONCLUSION:Central composite design is convenient to use and it has satisfactory predictability thus deserving popularization.

This report presents two cases of unilateral acute labyrinth loss resulted from injury,each showing delay in compensation possibly due to long-term administration of diazepam.The recent literature of the effects of the drugs onyestibular compensation is reviewed.The vestibular"suppressants"property of diazepam delays compensation when used on a long-term basis.However,it might be useful in controlling vege- tative symptoms and thereby possibly facilitate compensation when used on a short- tern basis.

Hightiter anti-idiotypic antibodies(Ab_2)sera and two monoclonal anti-idiotypic antibodies (McAb_2)were repared by immunizating syngeneic BALB/c mice wth a complex of 7A_4 monoclonalantibody(McAb_1)against the a eterminant of the Hepatitis B Surface antiger(HBsAg)。Both Ab_2sera and McAb_2 recognize the idiotype of aratope n 7A_4McAb_1.Ab_2 sera contain the antibodiesbinding specially to anti-HBs from other species(guinea pig、onkey、rabbit and goat)and the twoMcAb_2 can not bind to these anti-HBs.Therefore it is thought that the two McAb_ re noninternalimage(Ab_2?)anti-idiotypic antibodies,this study proves that the McAb_1 against he eterminantof the HBsAg are different in their paratope,The McAb_2 can be used to stinguish the parotope onthe McAb_1 as a biological probe.

40 rabbits are used to study the effects of phaco-emulsification and extracap-sular lens removal or; corneal endothelial cells and corneal thickness.With the specular microscope, the preoperative cell morphology, cell density and thickness of cornea are revealed. The endothelial cell counts decrease 16% (at central) and 14% (at the periphery) after the surgery with phaco-emulsification and 25% (central) and 22% (periphery) with extracapsular lens removal. Corneal thickness increases in both groups. Scanning electron microscopy shows some alterations in morphology of endothelial cell injury significantly different in the 2 groups. According to these results the causes of corneal thickness increasing and mechanism of endothelial cell injury are approached and a new procedure preventing the cell injury and decreasing cornea edema in both groups is designed.

The paper introduces the bar code technology applying in medical reports management with the combination experience of Taizhou hospital, including relevant equipments and applying methods, statistics mode for bar code medical records circulation: medical records recovery subsystem, circulation management subsystem, query and return subsystem, bar code production subsystem, etc, as well as noted issues during the operation.

This article discussed the reform of library cataloguing induced by library standardization and automation from four aspects of expansion of cataloguing scope, the change of cataloguing methods, deep revealing of literature cataloguing, and the elevation of personnel quality.

Objective To investigate the psychological state and its correlation factors of family members of elderly cancer patients. Methods A total of 76 family members of elderly cancer patients were investigated with questionnaires with Zung's self-rating anxiety scale (SAS) and self-rating depression scale (SDS). Their psychological state and its correlation factors were analyzed. Results Incidence rate of anxiety of elderly cancer patients' family members was 52.63%, and incidence rate of depression was 46.05%. The mean standard score of SAS and SDS of elderly cancer patients' family members were both significantly higher than domestic norm. Difference of family member's gender, ways to pay health care fee, pain degree and disease condition led to different SAS and SDS score. Conclusions Family members of elderly cancer patients possessed different degree of psychological obstacle which related with multiple factors. Medical staff should not only think highly of patients' psychological state, but also their family members'. And meanwhile they should take corresponding strategy to reduce the incidence rate of anxiety and depression state in those family members.

Objective To study the effects of sucking sputum with face upwards and neck raised in order to supply a new method for sputmn sucking.Methods One hundred and twenty-three patients were randomly divided into the experimental group(n=61)and the control group(n-62).The experimental group adopted modified mode:cleaned up the sputum within the mouth and nasal cavities with the traditional manner firstly,then the patients lay down,the nurses raised the patients'neck softly with one hand,removing the pillows,while putting the hypothenar of the other one on his forehead,kept the airway open to suck sputum.The control group adopted common mode,but using the modified method when the common mode failed.Results There was significant difference in phlegm sucking effect between the two groups(P＜0.01).Besides,the first-time success rate d tube insertion,incidence of trachcotomy,mucosal injury and hemorrhage and satisfaction degree of patients'family were statistically different between the two groups(P＜0.01).Conclusion Sucking sputum with face upwards and neck raised waS superior to the traditional one.