100?g/ml was(65.6?5.8)g/L and that of those patients with their VAP0.05).CONCLUSION:Blood concentration of VAP is affected by the plasma level of TP,too low TP level is likely to induce drug poison.

Objective To study the effects of sodium nitropnisside on early left ventricular remodeling after acute myocardial infarction (AMI). Methods 50 patients with ST segment elevating AMI who hadn' t been PCI or thrombolysis because of the delayed visiting time or poverty were randomly devided into two groups. Treatment group (n = 26) was treated with Sodium Nitropnisside on the basis of routine therapy and control group treated with Nitroglycerol and ACEI/ARB. In 4th week after AMI,left ventricular systolic volume index( LESVI) ,left ventricular diastolic volume index ( LEDAI), left ventricular ejection fraction ( LVEF) and left bventricular diastolic early and advanced stage engorging velocity ratio(E/A) were detected by ultrasonography. Results LESVI and LEDAI were significantly decreased and LVEF and E/A were significant increased after treated with Sodium Nitropnisside. There was significantly difference between two groups. Conclusion Sodium Nitropnisside could effectively prevent and treat patients with early left ventricular remodeling after AMI.

Purpose To explore the role of expression of MMP-9 and MMP-13 in non-small cell lung cancer ( NSCLC) , and to investi-gate their association with the clinicopathologic feactures and prognosis of NSCLC. Methods The expression of MMP-9 and MMP-13 was detected in 88 NSCLC tissues and 18 adjacent normal tissues by immunohistochemistry SP method. Results The expression of MMP-9 and MMP-13 was higher in NSCLC than that in adjacent normal tissues (P<0. 05), which was positively correlated with dif-ferentiation and lymph node metastasis (P<0. 05). The expression of MMP-9 was positively correlated with age (P<0. 05), which was positively correlated with the expression of MMP-13 in NSCLC ( P <0. 05 ) . The survival rates in positive expression group of MMP-9 and MMP-13 were significantly lower than that of the negative expression group by log-rank method comparing survival curves (P<0. 05). Cox model analysis showed that the tumor size, lymph node metastasis and MMP-13 positive expression were closely relat-ed with the prognosis of NSCLC (P<0. 05). Conclusion MMP-9 and MMP-13 both are associated with the metastasis, invasion and prognosis of NSCLC, and MMP-13 may mainly activate MMP-9 to participate the invasion and metastasis of NSCLC.

Objective To explore the in-patients' evaluation and the correlative requirement for the bachelor degree nursing students. Methods Investigated 10 patients by using the self-developed interview outline, and then summarized the key points of these talking. Results The evaluation from patients to bachelor degree nursing students had included 6 aspects: attitude, clinical nursing skills, knowing about the concrete condition of patients, the wide of nursing students' knowledge, the health education for patients and the ability of communication and cooperation. Conclusion Different have their own different emphasis when evaluate the nursing students, but the evaluation from patients were praiseful.

To compare the efficacy and side effects of bupivaeaine(Bup)at two concentrations and fentanyl for caudal analgesia in children. Method:One hundred-fifty children undergoing hernia repair procedures under caudal anesthesia, were randomly assigned to five groups. Group A: 1% lidocaine (Lid), group B: 10% Lid+0.1% Bup, group C: 1% Lid+0.25% Baeup, group D: 1%Lid+0.15%Bup with 2?g?kg~(-1) fentanyl, group E: 1%Lid+0. 25%Bup with 2?g?kg~(-1) fentanyl for caudal analgesia, The degree of pain(LPS), nausea and vomiting (NV) were as sessed at 4, 8, 12 and 24 h after operation. Result: The numbers of LPS

Objective To investigate the role of FHIT in NSCLC and the relativity between FHIT and cigarette.Methods 81 cases of NSCLC and 7 cases of the nomal lung tisses were examined for FHIT by immunochemical(S-P).Results The postive expression rates of FHIT were significantly lower than those in nomal lung tisses(P

0.05).TNF-? mRNA of intervenient group was significantly increased than that of control group(P

0.05),but the relative levels of the mRNA of TNF-? and leptin were significantly down-regulated(P

Objective To make out the effective method of emergency materials management. Methods According to the native regular emergency diseases and the orders of superior section make out a general method for emergency materials management. Results This general management method can effective solve the problems which have existed in the aspect of emergency materials management. Conclusion By using general management method could advance the quality of first aid.

Objective This study was designed to determine the expression ofgeneproducts of phosphatase and tensin homoligy deleted onehromoseten(PTEN)and DNA content in non small cell lung cancer(NSCLC)tissue and investigate their association with the invasion and metastasis of NSCLC.Methods The expression of PTEN were detected in 78 cases of lung cancer tissues by immunohistochemistry SP methods,DNA content in 30 cases of lung cancer tissues was examined by flow cytometry.Results The rate of total expression depletion of PTEN was 42.3%.The rates of PTEN expression depletion in lymph node metastasis group and no lymph node metastasis group were 52.1%and 26.7%respectively,with significantant difference(P＜0.05).The patients who had high expression of PTEN had a longer survival time.The range of the DNA index(DI)distribution ranged from 1.04 to 1.93,the DNA index and aneuploid tumor had a positive correlation with the lymph node metastasis,with the increased of TNM stage,the DI and the rate of DNA aneuploid increased(P＜0.05).Conclusions Expression of PTEN is associated strongly with lymph node metastasis of lung cancer,correlations exist between DNA content and TNM stage,lymph node metastasis.They are indications of metastasis potential and prognosis of lung cancer.