[bjective]To summarize Professor YU Xinwei 's experience in treating Hashimoto's thyroiditis. [Methods]The article discusses the essentials of clinical dialectical experience of Professor YU Xinwei in the diagnosis and treatment on Hashimoto's thyroiditis.The article also illustrates and analyses a medical record. [Result]Professor YU considers that treatments of Hashimoto thyroiditis should start from the liver spleen and kidney,combine Chinese traditional and western medicine,medicate stagedly and reasonably,while paying attention to female patients.[Conclusion]Professor YU Xinwei distinguishes characteristics in therapy and the rich experience,simultaneously the clinical efficacy is obvious.

To investigate the correlation between cerebral infarction and carotid atherosclerosis.Methods:Bilateral carotid atherosclerotic plaques,intima-media thickness (IMT),and stiffness coefficient (β) in 60 patients with cerebral infarction were detected by high-frequency color Doppler imaging,and they were compared with the control group (n=60).Results:The detection rate of plaque in the cerebral infarction group was significantly higher than that in the control group (90% vs 28%,P<0.005); the constituent ratio of soft plaques in the cerebral infarction group was significantly higher than that in the control group (P <0.01),and the constituent ratio of flat and hard plaques was significantly lower than that in the control group (P<0.005); IMT and β values in the cerebral infarction group were significantly higher than those in the control group (P<0.01).Furthermore,IMT had significant positive correlation with β values (P<0.01).Conclusions:Carotid atherosclerosis is closely correlated with cerebral infarction.

Objective To observe the efficacy of Buyanghuanwu herbal decoctions on microalbuminur in noninsulin-dependent diabetes mellitus. Methods Sixty-six patients with noninsulin-dependent diabetes mellitus patients with 30～300 mg/24 h microalbuminur were randomly divided into the treated group (treated with Buyanghuanwu herbal decoctions) and the control group (treated with injection of Huangqi). The clinical efficacy was observed and levels of blood-fat, hemorheology and microalbuminur were determined. Results The levels of blood-fat, hemorbeology and microalbnminur were decreased in treated group. Comparison between the two groups showed significant difference (P

Objective To observe the clinical efficacy of Cardiotonic Pill and Monopril in treating congestive heart failure disease. Methods Seventy-eight patients with congestive heart failure were randomly divided into two groups. The control group received routine treatment (Monopril), and the treated group were given Cardiotonic Pill besides routine treatment. The symptoms, physical signs and the parameter and classify of cardiac function were evaluated in all patients. Results The symptoms and physical signs after treatment were better than before. The cardiac function were improved. Comparison between the two groups showed difference (P

AIM:To observe the effects of Tianma Gouteng Decoction on mRNA expression of L-Type Calcium Channel ?1 C subunit (CaL-?1C) and plasma membrane calcium-ATPase (PMCA1) in vascular smooth muscle cells of spontaneously hypertensive rat (SHR). METHODS:Twelve-week-old SHRs were assigned randomly to 5 groups:group A (treated with Tianma Gouteng Decoction),group B (treated with Tianma Gouteng Decoction excluded concha haliotidis),group C (treated with Nifedipine),group D (treated with concha haliotidis),group E (treated with normal sodium,NS),each group consisted of 9 rats was adminstrated,once a day for 4 weeks and mRNA expression of CaL-?1C and PMCA1 was measured with RT-PCR half-fix-quantify method. RESULTS:After 4-week-treatment,both Tianma Gouteng Decoction,Tianma Gouteng Decoction excluded concha haliotidis and Nifedipine could regulate downward mRNA expression of CaL-?1C in vascular smooth muscle cells and regulate upward mRNA expression of PMCA1 in vascular smooth muscle cells,concha haliotidis has no effect on mRNA expression of CaL-?1C and PMCA1. CONCLUSION:Tianma Gouteng Decoction can regulate downward expression of CaL-?1C,and regulate upward expression of PMCA1 at the same time,and meliorate the Ca 2+ overload in vascular smooth muscle cells with hypertension.

Objective To investigate the literature research focus of Chinese Pediatric Emergency Medicine.Methods The papers published in Chinese Pediatric Emergency Medicine from 2006 to 2011 and indexed by wanfang database served as the basic data sources.Four thousands and fifty-four keywords were collected from 1194 literature.Keyword frequency statistics and the co-occurrence analysis were made by using bibliographic item co-occurrence matrix builder,and cluster analysis was made using SPSS 11.5 software.Results Newborns,premature,hand,foot and mouth disease,mechanical ventilation,sepsis,congenital heart disease was the top 10 high-frequency keywords.Cluster analysis diagram showed the research focus from articles published in Chinese Pediatric Emergency Medicine for the past six years,which included:(1) hand,foot and mouth disease; (2) prognostic factors for septic shock; (3) acute lung injury and acute respiratory distress syndrome; (4) neonatal asphyxia induced hypoxic-ischemic encephalopathy; (5) the disease of premature infants ; (6) the treatment of congenital heart disease complicated with severe pneumonia and heart failure; (7) the pathogens and drug resistance analysis of pediatric intensive care unit-acquired infection; (8) sepsis.Conclusion The main study law and direction of Chinese Pediatric Emergency Medicine in the past six years are proved by keyword co-words cluster analysis.

Objective]To research the impact of Danxi’s medical science on Kampo medicine system and summarize its development in Japan,for providing ideas for the research of Chinese medicine. [Method]Learning Zhu Danxi related books and Kampo medicine literature, analyse the impact of Danxi ’s medical science on each genre of Japan Kampo medicine,explain the role of Danxi ’s medical science in the formation and development in Japan Kampo medicine system,and ummarize its development path in Japan.[Result]The development of Danxi ’s medical science in Japan experienced ups and downs, combined with local realities,and derived more Japanese-oriented medical theories. [Conclusion]Danxi ’s medical science not only for the formation of Japanese Kampo medicine system plays an important role, but also has a profound impact on Japan's three Kampo medical genre.Its development track is worth thinking and summarizing.

Objective:To improve the CT bulb tube cooling rate and the testing method of the CT bulb tube temperature, and provide more stable platform for better bulb tube protection and longer life-span. Methods: The designed specified cold air machine could transfer the dry cold wind into machine rack, which can lower the ambient temperature of the machine rack and increase the air flow inside the machine rack and promote the efficiency of the heat exchange of the bulb tube oil cooling circuit. Results:the design of this system’s joint is light and handy, which could collect the instantaneous temperature change of the bulb tube, and carry out simple man-machine interaction monitoring. Conclusion:According to the bulb tube oil-way temperature and ambient temperature and relative humidity, the computer can dynamically adjust the refrigerating capacity and operation/cease of the air cooler. Then it can constitute the closed control loop, and accelerate the efficiency of the bulb tube’s heat dissipation, and promote the heat capacity of the bulb tube equivalently.

AIM: Through detecting bone marrow angiogenic mediators and inhibitors in aplastic anemia(AA) patients,the value of angionesis in AA pathogenesis was elucidated.METHODS: The patients were divided into severe AA group(SAA,8 patients),non severe AA group(NSAA,10 patients),and normal control group(7 persons),5 patients were observed before treating(group beginning) and getting improvement(group improving).The angiogenic mediators vascular endothelial growth factor(VEGF) and bFGF were detected by ELISA,angiogenic inhibitors IFN? and TSP were detected by ELISA and flow cytometry,respectively.RESULTS: The levels of VEGF were lower in SAA group and NSAA group than those in control group significantly(P

Objective To analyze the clinical characteristics of narcolepsy in children with obesity,and to e-valuate the impact of obesity on narcoleptic children clinically. Methods Forty cases first diagnosed as narcolepsy were recruited in the study who to see doctors at the Department of Neurology,Children's Hospital of Capital Institute of Pediatrics,from July 2012 to January 2015. According to diagnostic criteria for obesity by the body mass index(BMI) growth curve for the Chinese children and adolescents,they were divided into the obese group and the nonobese group. The general clinical data of 2 groups were analyzed,and the related metabolic indexes and the whole night polysomnog-raphy(PSG)of 2 groups were studied. Results In this group,male versus female 3: 1,obesity was found in 21 cases (52. 5% )and nonobesity was found in 19 cases(47. 5% )from the samples. The mean BMI of all patients was (21. 55 ± 3. 11)kg/ m2 . The average BMI of the obese group was(23. 09 ± 2. 46)kg/ m2 ,and BMI of the non - obese group was(19. 85 ± 2. 89)kg/ m2 . Obese children were younger at the onset of disease and by the time of diagnosis age [(7. 94 ± 2. 22)years old,(8. 76 ± 2. 36)years old]than nonobese children[(10. 75 ± 3. 10)years old,(12. 51 ± 2. 88)years old]. The fasting blood glucose and blood lipid in all patients were normal,and there was no significant difference between 2 groups. The total sleep time,sleep efficiency and the ratio of rapid eye movement(REM)phase of the obese group[(397. 45 ± 53. 76)min,(68. 70 ± 8. 90)% ,(18. 37 ± 4. 39)% ]were significantly lower than those of the non - obese group[(449. 95 ± 86. 49)min,(76. 58 ± 13. 60)% ,(22. 19 ± 6. 34)% ]. According to the sleep structure,the percentage of stageⅠnon rapid eye movement(NREM)sleep in the obese group[(20. 90 ± 6. 38)% ] was more than that in non - obese group[(16. 26 ± 4. 22)% ]. There was no difference between the percentage of stageⅡNREM sleep in the obese group[(42. 59 ± 5. 52)% ]and the non - obese group[(38. 54 ± 8. 74)% ]. Stage Ⅲ + Ⅳ(slow wave sleep)NREM sleep ratio in the obese group[(18. 14 ± 6. 97)% ]was significantly lower than that in the non - obese group[(22. 60 ± 5. 69)% ]. Conclusions Obesity is one of the most common comorbids in narcolepsy, which affects more than 50% of narcoleptic children,mostly younger at disease onset. The narcolepsy children with obe-sity has total sleep time decreased,sleep efficiency reduced and sleep structure disorder is more obvious. To improve the realization of obesity in narcolepsy children and early treatment is the key to the success of the therapy.