Objective:To study the quality standard for Xinkang capsules. Methods:Panacis quinquefolii Radix, Chuanxiong Rhizoma and Ophiopogonis Radix were identified by TLC. The content of puerarin in Xinkang capsules was determined by HPLC. Results:The spots in TLC were clear. The linear range of puerarin was 108-648 μ g(r = 0. 999 9). The average recovery of puerarin was 97. 33%(RSD = 0. 4%). Conclusion: The method is simple, repeatable and accurate, which can be used in the quality control of Xinkang capsules.

Many tumorigenesis in human are closely linked to the functional loss of P53. The tumor-suppressive functions of P53 are abrogated by mutations, but in 50% of all tumors it remains wild type. In these cases, loss of P53 tumor-suppressive function mainly results from the abnormal methylation of 5' CpG islands of tumor suppressor genes such as INK4a, ARF and ASPP. Restoring to normal methylation state of these genes might provide a new strategy for tumor therapy.

Recently,radiation-inducible gene therapy is one of new researchs in tumor therapy.In one side,the method associate radiation therapy with gene therapy,acting as synergistic effect;another side,radiation is targeting and inducible,implementing spatial and temporal control of gene expression.Related researchs have gained advances.This paper concisely reviews the status quo and the prospective applications.

Objective To study the effect of TanshinoneⅡA(TSN) on vascular smooth muscle cells(VSMCs) induced by high glucose and its relationship with MAPK signal pathway.Methods After the establishment of the model of diabetic rats,the aortic of rats was isolated and cultured.DNA synthesis was analyzed by ELISA of BrdU.The activity of MAPK was measured by liquid scintillation counting.Results TSN inhibited the proliferation and DNA synthesis of vascular smooth muscle cells from diabetic rats in dose-dependent manner.TSN at the dosage of 0.5 mg/L significantly decreased the activity of MAPK as well as of U0126.Conclusion The effect of TSN on the proliferation and DNA synthesis of vascular smooth muscle cells from diabetic rats is potentially mediated by inhibition of MAPK.

Many tumorigenesis in human are closely linked to the functional loss of P53. The tumor-suppressive functions of P53 are abrogated by mutations,but in 50% of all tumors it remains wild type. In these cases,loss of P53 tumor-suppressive function mainly results from the abnormal methylation of 5' CpG islands of tumor suppressor genes such as INK4a,ARF and ASPP. Restoring to normal methylation state of these genes might provide a new strategy for tumor therapy.

Ethyl pyruvate ( EP) is a stable lipophilic ester derivative of pyruvate with many pharmacological actions confirmed by researches , the anti-tumor effects of EP has attracted the attention of many domestic and foreign scholars .EP exerts antitumor activi-ty through several ways , such as inhibiting proliferation , inducing apoptosis , inhibiting angiogenesis , blocking cell cycle .This paper briefly reviews the rencent findings of antitumor function of EP .

A retest of 30 deaf children(58 ears) being trained in our centre who used hearing aids for at least half a year showed that two children(2 ears) suffered from hearing loss. To inquire into the cause of hearing loss, we analysed the frequency,range,gain,SSPL 90. volume control of the hearing aids worn by the children as well as the auditory training habits if the deaf children's parents and teachers,compared the children's hearing before and after using the hearing aids and pointed out the possible reasons that caused the children's hearing loss. Here.We sum up the aspects that should be paid attention to when testing and selecting hearing aids for deaf children.

AIM: To instruct the self-care ability of patients underwent the kidney transplant with Orem self-nursing theory. METHODS: A total of 118 patients received kidney transplant were recruited from the Ruikang Hospital Affiliated to Guangxi College of Traditional Chinese Medicine and the Yiyang Municipal People's Hospital from January 2003 to June 2006, with all the patients' informed consents. The subjects were divided into two groups:①Orem self-nursing theory group (n =68): Taking the Orem self-nursing theory as the instruction, the self-care ability and self-care defect of patients were appraised. They were treated with different nursing systems and healthy educations, participated in designing the nursing plan and activity.②Control group (n =50): The patient of this group received usual care. The self-care ability of patients in the two groups were evaluated 1, 3, 6 months after the kidney transplant, grading Ⅰ as completely recovery to routine work; Ⅱ as semi-recovery to routine work and daily life was revived. Both Ⅰ and Ⅱ grades indicated the good quality of life (QOL). RESULTS: All the 118 postoperative patients were involved in the result analysis.①None of Orem self-nursing theory group appeared the complication.②The good and excellent rate of QOL in patients of Orem self-nursing theory group was significantly higher 3 months postoperation than 1 month postoperation (59%, 13%, P

OBJECTIVE:To optimize?-cyclodextrin inclusion process in the inclusion of volatile oil compounds of peppermint,biond magnolia flower and agastache rugosa in biyuanling granules.METHODS:Orthogonal experiment was performed,the inclusion process was evaluated with inclusion rate of volatile oil,recovery rate of inclusion compound,extract ratio of inclusion compound as indexes.RESULTS:The optimized inclusion condition was as follows,the ratio of volatile oil to?-cyclodextrin was1∶8(ml/g)with10min ultrasound time and20℃ultrasound water temperature.CONCLUSIONS:The optimized method was simple and efficient,and suitable for industrialized production.

Objective To evaluate the effect and safety of point injection and em bedding therapy on postoperative pain of hemorrhoid patients. Me thods Totally 105 hemorrhoid patients were rand omized into a treatment group (54 cases) and a control group (51 cases). The tre atment group was treated by point injec tion and embedding therapy at Changqiang point (GV 1) under the local anesthesia . The control group was treated by Indometacin Suppository after operation. On the fir st, second, four th and seventh day of the treatment, the pain occurrence, pain severity, and com prehensive effect scores were recorded for the evaluation of therapeutic effect and safety. Results On all interview periods, the compr ehensive effect score, pain occurrence, pain severity, patient satisfaction, occurrence of untoward eff ect, complications, and analgesics combination in the treatment group were all superior to those in the control group (P