engue fever is a vector-borne infectious disease caused by dengue virus and transmitted by Aedes mosquitoes. Affected by globalization, urbanization, and climate change, the prevalence of dengue fever is expanding globally, and the number of infections is still increasing continuously, making its prevention and control situation increasingly severe. In preventing and controlling dengue fever, the control of vector Aedes mosquitoes remains the most effective method. Aedes mosquito control should take into account the combination of conventional control and emergency control, the overall coordination and complementation of comprehensive environmental control, biological control, chemical control, and other control means, and the adoption of sustainable control strategies and measures in accordance with the local conditions; in addition, scientific research and international cooperation should be strengthened in the monitoring, diagnosis and treatment of dengue infections, and the development of vaccines and specific drugs, to add more effective options for the prevention and control of dengue fever. Currently, the prevention and control of dengue fever still faces many challenges, such as the continued geographical expansion of dengue prevalence, the widespread resistance of Aedes mosquito populations to insecticides, and an increase in severe cases caused by antibody-dependent enhancement. This article reviews the global and domestic dengue epidemic and control situations, as well as future challenges and strategies, providing evidence for dengue fever prevention and control.