1.Epithelial-Myoepithelial carcinoma of the lacrimal gland - Case report and review of literature
Mara Augustine S. Galang ; Gary John V. Mercado ; Armida L. Suller Pansacola ; Jose M. Carnate Jr.
Philippine Journal of Ophthalmology 2023;48(2):91-96
Objective:
To describe the clinicopathologic features and outcome of a patient with epithelial-myoepithelial carcinoma of the lacrimal gland who underwent modified lateral orbitotomy with en toto removal of the lesion and adjuvant radiotherapy.
Methods:
This is a case report.
Results:
A 31-year-old Filipino male seafarer presented with a 2-month history of an enlarging left superotemporal orbital mass and inferonasal displacement of the globe. Magnetic resonance imaging revealed a superotemporal extraconal mass within the lacrimal sac fossa with evidence of osseous infiltration of the superolateral orbital rim. Modified lateral orbitotomy was performed with en toto removal of the lesion and the clinically infiltrated adjacent lateral bony margin. Histopathologic diagnosis of epithelial-myoepithelial carcinoma of the lacrimal gland was made based on the classic and distinct biphasic morphology and was confirmed with immunohistochemistry studies (cytokeratin-7, S-100, and p63). Systemic surveillance using positron emission tomography and computed tomography scan with contrast revealed no evidence of regional or distant metastasis. Adjuvant radiotherapy of the orbital area was performed for increased local control. Twelve months postoperatively, the patient showed no evidence of tumor recurrence.
Conclusion
Epithelial-myoepithelial carcinoma of the lacrimal gland is a rare condition, and this is the first documented case from the Philippines. Accurate diagnosis is necessary for appropriate treatment. It should be included in the differential diagnosis of infiltrative lesions in the lacrimal gland fossa.
Lacrimal Apparatus
2.Cyst Between the Levator Aponeurosis and the Palpebral Conjunctiva.
Hyo Kwang PARK ; Wha Sun CHUNG
Journal of the Korean Ophthalmological Society 1995;36(1):125-129
Cysts of accessory lacrimal gland are rare. They are generally retension cysts that result from obstruction of the excretory duct and are found between the palpebral conjunctiva and the levator aponeurosis. We experienced three cases of subconjunctival cyst in the upper fornix. Histopathological examination showed the cysts lined by two layers and occasionally one layer of epithelium. These cysts seem to be originated from Krause's gland, considering their anatomical location and histopathological findings.
Conjunctiva*
;
Epithelium
;
Lacrimal Apparatus
3.Primary Adenocarcinoma of the Lacrimal Gland.
Sang Oon BAEK ; Yoon Jae LEE ; Suk Ho MOON ; Young Jin KIM ; Young Joon JUN
Archives of Plastic Surgery 2012;39(5):578-580
No abstract available.
Adenocarcinoma
;
Lacrimal Apparatus
4.Primary Adenocarcinoma of the Lacrimal Gland.
Sang Oon BAEK ; Yoon Jae LEE ; Suk Ho MOON ; Young Jin KIM ; Young Joon JUN
Archives of Plastic Surgery 2012;39(5):578-580
No abstract available.
Adenocarcinoma
;
Lacrimal Apparatus
5.One Case of Ectopic Lacrimal Gland in the Orbit.
Jin Soo KANG ; Ho Kyun CHO ; Kyung Hwen SHYN
Journal of the Korean Ophthalmological Society 1989;30(6):1007-1011
The medical literature contains few reports of ectopic lacrimal gland. Ectopic lacrimal gland has been observed in the eye and in various sites in the ocular adnexa. The authors had experienced one case of ectopic lacrimal gland in the super olateral side of orbit. The authors report this case with the review of literatures.
Lacrimal Apparatus*
;
Orbit*
6.What Lurks Beneath: Lacrimal Gland Adenocarcinoma Dedifferentiation to Sarcomatoid Carcinoma
Farrah-Hani Imran ; Muthukumaran Guhan ; Enda Kelly ; Jegan Thanabalan ; Farizal Fadzil ; Faridah Hanum
Journal of Surgical Academia 2015;5(2):70-74
This was a case of a young lady presenting with 10 year history of a mass in the right eye. It was found to be an
adenocarcinoma of the lacrimal gland from histopathological biopsy. She underwent wide excision, orbital
exenteration and reconstruction with a free rectus abdominis flap. Unfortunately, she had a tumour recurrence which
was not controlled by radiotherapy and a second excision. The behavior of the tumour was aggressive, resulting in
widespread metastases. She passed away within a year of her presentation. Of note, the histopathology report from
the second excision turned out to be sarcomatoid carcinoma. This is described in the literature as dedifferentiation, or
high grade transformation (HGT). Occurrence of dedifferentiation in salivary gland tumours is well-established, but
not as well-described in lacrimal gland tumours. In this case, there was a severely delayed presentation of a lacrimal
gland adenocarcinoma in a young person, which underwent dedifferentiation into a sarcomatoid carcinoma. This
phenomena is associated with aggressive tumour biology behavior and poor prognosis, despite surgery and
radiotherapy.
Adenocarcinoma
;
Lacrimal Apparatus
7.High-grade Mucoepidermoid Carcinoma of the Lacrimal Gland.
Korean Journal of Ophthalmology 2018;32(5):426-427
No abstract available.
Carcinoma, Mucoepidermoid*
;
Lacrimal Apparatus*
8.Cytopuncture microbiopsy during transcanalicular endoscopic lacrimal duct recanalization: A novel approach
Reynaldo M. Javate ; Rolando A. Lopez
Philippine Journal of Ophthalmology 2023;48(2):97-101
Objective:
To describe the cytopuncture microbiopsy (CM) technique performed during transcanalicular endoscopic lacrimal duct recanalization (TELDR) in patients with primary acquired nasolacrimal duct obstruction (PANDO) as an alternative to open biopsy, the standard method used in collecting specimen.
Methods:
This is a noncomparative, interventional case series with histopathologic correlation. Patients diagnosed with complete PANDO who underwent TELDR with balloon dacryoplasty and silicone intubation with CM at University of Santo Tomas Hospital from October 2014 to January 2017 were included.
Results:
Twenty (20) tissue specimens from the lacrimal sac and nasolacrimal duct were obtained from 18 patients. There were 16 females and 2 males included in the study. Mean age was 57.5 years. All specimens revealed few clusters of benign epithelial cells with few degenerated mononuclear cells and lymphocytes, and singly scattered lymphocytes that are set in fibrinous background. Tissue cytology studies were negative for malignant cells.
Conclusion
CM is a minimally invasive procedure that offers an alternative to open biopsy technique that can be done routinely during TELDR.
Dacryocystorhinostomy
;
Lacrimal Apparatus Diseases
9.Correspondence among the Canaliculus Irrigation Test, Dacryocystography and Jones Test in the Epiphora Patients.
Chang Ho KIM ; Helen LEW ; Young Soo YUN
Journal of the Korean Ophthalmological Society 2007;48(8):1017-1022
PURPOSE: The correspondence between the canaliculus irrigation test, dacryocystography, and Jones test in patients with epiphora was investigated. METHODS: The study included 494 eyes of 359 patients who complained of epiphora and underwent both canaliculus irrigation test and dacryocystography from May 2001 to March 2006. Sixty-eight eyes from 34 patients diagnosed with functional lacrimal duct obstruction took Jones tests. Factors such as age, sex, duration of epiphora, and site of obstruction were analyzed in terms of correspondence of the tests. RESULTS: Between the canaliculus irrigation test and dacryocystography, correspondent rate was 55%. Correspondence had no relation to patient age, sex, duration of epiphora, or site of obstruction. Between Jones test and dacryocystography, the correspondent rate was 47%. Factors affecting the correspondences were not significantly found. CONCLUSIONS: A canaliculus irrigation test can give useful information with high correspondence rate of dacryocystography in the case of 'not pass' or 'pass without regurgitation'. Therefore dacryocystography should be utilized in "pass with regurgitation" cases by canaliculus irrigation test.
Humans
;
Lacrimal Apparatus Diseases*
;
Lacrimal Duct Obstruction
10.Nasolacrimal Ostium after External Dacryocystorhinostomy.
Journal of the Korean Ophthalmological Society 2006;47(3):343-348
PURPOSE: To evaluate the internal ostium and lacrimal sac change after external dacryocystorhinostomy (DCR) using digital subtraction dacryocystography (DCG). METHODS: Between May 2003 and July 2004, digital subtraction DCG was performed to assess the ostium and lacrimal sac 6 months after external DCR in 48 patients (n=50 eyes). RESULTS: The lacrimal sac had reformed in 45 (90%) eyes. Mean ostium size was 2.4 mm (0.5~6.1 mm) and these were located at the inferior part of the reformed sac in 39 eyes (78%). Patients with a fistula-type internal ostium, of which the lacrimal sac had not reformed, often complained of epiphora (p=0.005). CONCLUSIONS: Digital subtraction DCG showed successful anatomic changes in the distal lacrimal pathway and confirmed that the internal ostium contracts into a relatively small ostium after DCR. A fistula-type internal ostium may explain the pathophysiology of functional failure after successful DCR.
Dacryocystorhinostomy*
;
Humans
;
Lacrimal Apparatus Diseases