1.The comparision of in vitro antibacterial activities of two drugs for ophthalmia neonatorum prophylaxis
Cai LIN ; Dong LUO ; Lühua ZHONG
Chinese Pharmaceutical Journal 1999;(2):111-
OBJECTIVE:To eualuate in vitro antibacterial activities of silver nitrate and povidone-iodine for preventing ophthalmia neonatorum. METHODS:Minimal inhibitory concentration(MIC) and mininmal bactericidal concentration (MBC) were deter-mined by double broth dilution method. RESULTS:For Stapanrens Streppnenmonia and N gonorhveae,the MIC50 of silver nitrate were<4~8μg.ml-1 and its MIC90 were 8~32μg.ml-1.The MIC50 of povidone-iodine were64~256μg.ml-1 and its MBC90were 512 μg.ml-1. CONCLUSION: Silver nitrate and povidone-iodine exhibited activities against common pathogens of ophthalmia neonatorum isolates.Silver nitrate was more active than povidone-iodine.
2.Variation of gross tumor volume and clinical target volume definition for lung cancer
Jun LIANG ; Minghui LI ; Dongfu CHEN ; Jima Lü ; Guangfei OU ; Zhouguang HUI ; Guishan FU ; Zhong ZHANG ; Rong ZHENG ; Jianrong DAI ; Lühua WANG
Chinese Journal of Radiation Oncology 2011;20(4):282-285
Objective To study the variation of gross tumor volume (GTV) and clinical target volume (CTV) definition for lung cancer between different doctors.Methods Ten lung cancer patients with PET-CT simulation were selected from January 2008 to December 2009.GTV and CTV of these patients were defined by four professors or associate professors of radiotherapy independently.Results The mean ratios of largest to smallest GTV and CTV were 1.66 and 1.65, respectively.The mean coefficients of variation for GTV and CTV were 0.20 and 0.17, respectively.System errors of CTV definition in three dimension were less than 5 mm, which was the largest in inferior and superior (0.48 cm,0.37 cm,0.32 cm;F=0.40,0.60,0.15,P=0.755,0.618,0.928).Conclusions The variation of GTV and CTV definition for lung cancer between different doctors exist.The mean ratios of largest to smallest GTV and CTV were less than 1.7.The variation was in hilar and mediastinum lymphanode regions.System error of CTV definition was the largest (<5 mm) in cranio-caudal direction.