1.Effects of function-oriented training on the balance of stroke survivors and their ability in the activities of daily living
Minya ZHOU ; Kunqiang YU ; Lixiu WU ; Shufang LIN ; Ruhui LIN
Chinese Journal of Physical Medicine and Rehabilitation 2021;43(4):327-331
Objective:To observe any effect of function-oriented training on the balance of recovering stroke survivors and on their ability in the activities of daily living.Methods:Sixty stroke survivors in recovery were randomly divided into an observation group ( n=30) and a control group ( n=30). The control group received routine rehabilitation training, while the observation group underwent function-oriented training for 6 weeks. Before and after the intervention, both groups were evaluated using the Berg balance scale (BBS), the Fugl-Meyer lower extremity assessment (FMA-L), the timed up-and-go test (TUGT) and the modified Barthel index (MBI). Results:After the treatment, significant improvement was observed in all of the measurements in both groups. The improvements in the average BBS, FMA-L and MBI scores and in the TUGT times of the observation group were significantly better than those of the control group.Conclusion:Function-oriented training can improve the balance and the ability in the activities of daily living of stroke survivors more effectively than the routine therapy.
2.Effects of Electroacupuncture on Learning and Memory and Expression of Brain-derived Neurotrophic Factor and p75 Neurotrophin Receptor in Rats with Cerebral Ischemia-reperfusion
Xiaojie LI ; Ruhui LIN ; Jing TAO ; Congkuai ZHAO ; Kunqiang YU ; Chunyan LI ; Hongwei PENG ; Lidian CHEN
Chinese Journal of Rehabilitation Theory and Practice 2015;21(9):1020-1024
Objective To observe the effects of electroacupuncture on learning and memory, and discuss the therapeutic mechanism. Methods 45 Sprague-Dawley rats were randomly divided into sham group (n=15), model group (n=15) and electroacupuncture group (n= 15). The latter 2 groups were modeled with middle cerebral artery occlusion for 1.5 h and reperfusion. The rats of electroacupuncture group received electroacupuncture at Shenting (DU24) and Baihui (DU20) for 7 days. Learning and memory ability was tested with Morris water maze. Neurologic impairment was assessed with Longa's score. Their hippocampus were observed under HE staining and the level of brain-derived neurotrophic factor (BDNF) and p75 neurotrophin receptor (p75NTR) protein were determined with Western blotting. Results Compared with the model group, the latency of water maze decreased and the times crossing the platform increased in electroacupuncture group (P<0.05), while the Longa's score significantly reduced (P<0.05), and the lesion of nerve cells were alleviated, with the decrease of p75NTR and increase of BDNF in the ischemic hippocampus (P<0.01). Conclusion Electroacupuncture can improve the learning and memory of cerebral ischemia-reperfusion rats, which may relate with up-regulating BDNF and down-regulating p75NTR in hippocampus.
3.Relationship between Injury Sites, Pathological Types and Attention in Post Stroke Cognitive Impairment
Feiwen LIU ; Jia HUANG ; Jiao LIU ; Qin WANG ; Zhengkun LIN ; Kunqiang YU ; Haiyan SONG ; Xiaofeng LIANG ; Guohua ZHENG ; Jing TAO ; Lidian CHEN
Chinese Journal of Rehabilitation Theory and Practice 2016;22(4):443-447
Objective To study the relationship between injury site (right or left) or pathological type (hemorrhage or infarct) and atten-tion impairment in post stroke cognitive impairment (PSCI). Methods June, 2014 to June 2015, 49 patients with PSCI were assessed with Test of Attentional Performance (TAP) within 1 week of admission. The reaction time and the numbers of correct response were recorded. Results The reaction time of alertness (with or without alarm) was shorter in the patients with left infarction (Z=-2.32, t=-3.76, P<0.05), and the correct number of auditory was more (Z=2.42, P<0.05) than those with right infarction. The reaction time of incompatibility test and Go/Nogo test was shorter in patients with left hemorrhage than those with right hemorrhage (Z>2.32, t=-3.10, P<0.05). Conclusion A trend of lateralization was found in patients with PSCI, rather than in the pathology.