In order to assess the influence of habitual alcohol consumption on hepatic and pancreatic function, and on the disposal of carbohydrate and lipid, determination of serum hepatic and pancreatic enzyme levels, and serum glucose, insulin and triglyceride on oral glucose challenge was made in relation with the amount of consumed alcohol.
1. GOT, GPT and γ-GTP levels increased correlated with daily alcohol consumption, and γ-GTP was the most sensitive marker for alcohol consumption.
2. Habitual alcohol consumption reduced serum amylase and increased elastase 1 and trypsin, while the excursion of these enzyme levels remained within normal range. Because people with elastase 1 or trypsin levels beyond normal range was found more frequently than with amylase, the former two pancreatic enzymes might be better marker of alcoholic pancreatic injury than the latter one.
3. Alcohol dependency in daily caloric requirement elevated serum glucose and triglyceride in fasting and 2 hours after glucose challenge. Hyperinsulinemia after glucose challenge might indicate that moderate daily alcohol consumption induces insulin resistance resulting in deteriorated glucose disposal.

The future of Japanese agriculture depends a great deal on the young adult. In this study, preventive health strategies for young people living in a farming area are discussed. The following is a summary of the conclusions we have arrived at.
1. There is much to be desired in their eating habits. Hence, the necessity of drawing up adequate guidelines and educational programs.
2. Young men must be dissuaded from smoking cigarettes and drinking a lot.
3. There is too much stress in living and working environments.
4. Overworking must be avoided.
5. Individuals must realize the importance of protecting and promoting their own health.

Epidemiological investigations were made on carcinoembryonic antigen (CEA) levels in 3, 259 rural inhabitants and 3, 200 urban inhabitants. Abonormally high CEA levels were found in 12.0% of male rural inhabitants and 6.8% of male urban inhabitants. For women, the percentage was 2.4% in rural areas and 1.6% in urban areas. Correlations between high CEA levels and age were noted in men. However, cigarette smokers had higher CEA levels than non-smokers in both rural and urban areas irrespective of age. Smokers' CEA levels were higher rural areas than in urban areas. These disparites in CEA levels between rural and urban inhabitants were studied, but remain unaccounted for.

A 41-year-old woman liked farm chemical-free (pesticid-free) vegetables. She was admitted for severe upper abdominal pain. Biliary ascariasis was suspected upon abdominal ultrasonographic examination. ERC (Endoscopic Retrograde Cholangiography) was performed and a linear filling defect was shown in the bile duct. We diagnosed her case as biliary ascariasis. And then, we removed a worm from the bile duct using stone extracer basket forceps. After this, she was given pyrantel pamoate.Abdominal ultrasonographic examination was helpful in diagnostic screening for biliary ascariasis. ERC and basket forceps were useful in removing the parasite.
Biliary ; Ascariasis ; success ; Manufactured aid ; Endoscopic retrograde cholangiography

At institutions in 9 areas of all over Japan, epidemiological and clinical surveys and investigations have been performed on the relationship between alcohol drinking and health for inhabitants in agricultural and fishing villages. The ethanol cutaneous patch test showed about 40% ALDH2 defficiency in these subjects. There were remarkable defferences in the drinking behavior between these positive and negative 2 groups. Various factors affecting the drinking behavior of subjects are there congenital diathesis, sexual difference, natural and social differences as well as age and occupation. By drinking, various abnomalities have been observed in various indexes such as medical examinations namely, hepatic functions (γ-GTP, GOT, GTP, etc), lipids (HDL-C, TG, etc), circulating functions (blood pressure, pulse, etc), metabolisms (uric acid, blood sugar, etc), and pancreatic functions. Most of them are risk factors in adult diseases. Accordingly, through collective education for drinking, its effect can be observed earlier and it will be very important to educate individuals for health control.