1.Humanism Care For Uremia Patients
Chinese Medical Ethics 1995;0(04):-
Humanism care meets the need of the development of the whole society, the need of transformation of modern medicine pattern it is also the great need for uremia patients who thirst for health.Uremia patients with psychological distress will be greatly improved through following aspects: enhancing quality of medical staff,making more communications with patients and providing health education to them.In a word,humanism care for uremia patients will make them feel more love and improve their living states.
2.The effect of low molecular heparin and Galectin-3on the cell migration and proliferation of vascular endothelial cells
Yang DING ; Shengyun WAN ; Kun YE
Acta Universitatis Medicinalis Anhui 2017;52(5):651-655
Objective To explore the effect of the association of low molecular heparin and Galectin-3 on the cell migration and cell proliferation of vascular endothelial cell from mesenchymal stem cells.Methods Depending on the administration, this study was divided into four groups: low molecular weight heparin group, adding 20 mg/L low molecular weight heparin into the cells;Galectin-3 group, adding 5 mg/L Galectin-3 into the cells;combination group, adding 20 mg/L low molecular weight heparin and 5 μg/ml of Galectin-3 into the cells;control group, equal volume of PBS buffer into the cells.The proliferation of vascular endothelial cell was to be detected by EdU incorporation,the cell growth cycle of vascular endothelial cell was to be detected by flow cytometry,and the cell migration of vascular endothelial cell was to be detected by scrath test.Then to investigate the effect of different conditions on the migration and proliferation of vascular endothelial cell.Results The OD490 of MWH group, Galectin-3 group, combined group and control group were (0.285±0.018), (0.297±0.041), (0.351±0.016), and (0.233±0.005) respectively, which indicates that the combined group could increase the cell proliferation significantly(P<0.05).Cultured for 24 hours, the cell migration rate was(42.02±7.62), (45.82±3.96), (68.53±11.22),and (34.21±3.99), suggesting that combined group have the largest cell migration(P<0.05).Conclusion The association of low molecular heparin and Galectin-3 could improve the cell migration and cell proliferation of vascular endothelial cell from esenchymal stemcells significantly.
4.Relation of hepatitis C virus level and genotypes to response to interferon treatment
Kun LI ; Lihui WANG ; Jun YE
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Objective To investigate the relationship between HCV genotype and its level and the response to interferon (IFN).Methods HCV genotypes were detected by type-specific primes modified PCR assay.HCV-RNA levels were determined by branched DNA(bDNA) singnal PCR amplification fluorescence assay.The patients with chronic hepatitis C virus infection treated with IFN ? were divided into different groups according to genotypes or levels of HCV.Result Patients with pre-treatment HCV levels10 9 eq?L -1 showed partial responses (28 6%) or no responsces (28 6%).Stasistical analysis showed significant difference (P
5.Application status and evaluation of transilluminated powered phlebectomy in varicose vein surgery
Kun YE ; Huagang ZHU ; Kangmin YU
International Journal of Surgery 2011;38(6):402-404
Varicose veins is the main clinical manifestations of the chronic venous insufficiency.TIPP transilluminated powered phlebectomy,a new minimally invasive surgery,received much attention while surgical techniques aimed at treating varicose vein were constantly updated.In this article,TIPP in the varicose vein surgery is reviewed from its history,operating techniques and advantages,and TIPP's future is being prospected.
6.Programming and rebuild of network system in hospital information construction
Ye LUO ; Yutu TIAN ; Kun JIANG ; Haibo TU
Chinese Medical Equipment Journal 2004;0(08):-
Objective To construct a safe,stable and credible system for the running of network system and improve its application effect.Method Starting with the information system construction in Xijing hospital,the existent network system was programmed and rebuilt by establishing a assistant switch core and constructing multi-center redundancy link.Conclusion The rebuilt information system of Xijing hospital attains the anticipated effect,and shows rationality and practicability in use.What's more,combined with actual experience,the rebuild of hospital network system was summarized and suggestions were given.
7.Analysis of Drug Use in 34 Hospitals from Chongqing Area during 2012-2014
Ye YU ; Yu ZENG ; Shurong JIN ; Lei DU ; Kun HUANG
China Pharmacy 2016;27(17):2329-2332,2333
OBJECTIVE:To provide reference for drug production,parchase and use in local governments,health care depart-ment,hospitals,manufacturers and sales enterprises,etc. METHODS:By consumption sum sorting method,the information of 14 categories and key types in 34 hospitals from Chongqing area during 2012-2014 were analyzed statistically such as sales,produc-tion manufacturers. RESULTS:The consumption sum of 34 hospitals from Chongqing area increased by 15%-17% during 2012-2014. The consumption sum and proportion of anti-infective drugs showed a downward trend,decreasing by 3.28%. Those of respi-ratory system drugs and anti-tumor drugs had the largest increase,with increasing rate of 79.01% and 69.39%,respectively. Do-mestic drugs accounted for about 73% market share,and sales of imported drugs increased more than domestic and joint-stock drugs,increasing by 40.17%. Among 6 Chongqing pharmaceutical manufacturers on the top 100 consumption sum shortlist,total consumption sum of 3 manufacturers had increased;the consumption sum of top 10 foreign pharmaceutical manufactures increased year by year. CONCLUSIONS:The consumption sum of drugs is increasing in Chongqing area. Anti-infective drugs accounted for less than 16%,which is the achievements of clinical application of antibiotics special rectification activities for 3 years. Both respi-ratory system disease and malignant tumor have high incidence in Chongqing area. Domestic drugs still are main types in hospital. Foreign manufacturers develop well in China,but Chongqing pharmaceutical manufacturers show unsatisfactory development pros-pect.
8.Correlation between Serum Apolipoprotein M Expression and Disease Activity in Patients with SLE
Xiaoyan CAO ; Kun FU ; Qing YE ; Fengxia LI
Journal of Modern Laboratory Medicine 2017;32(1):138-140,143
Objective To study the level of serum apolipoprotein M and its disease activity index in patients with SLE.Meth-ods 65 cases of systemic lupus erythematosus patients in Shiyan City Renmin Hospital from January 2013 to December 2015 were selected.In addition,female workers 20 people as control group.Tested the level of serum lipids,Apo,CRP and ESR.Compared the expression level with Apo M and Apo A1 ,and Apo B and the degree of disease activity.Results Activi-ty group and Apo A1 ,HDL,TC,remission group,Apo and M were lower than the control group,the difference was statisti-cally significant (P<0.01).Active group,remission group LDL and Apo B was higher than the control group,and the difference was statistically significant (P<0.01).Active group and remission group TG was higher than the control group, but no significant significant differences (F=0.061,P=0.937).Apo A1 and total cholesterol,high density lipoprotein, smooth protein was positively correlated (P<0.05),and ESR was negatively correlated with the 24h urinary protein (P<0.05).Apo B was positively correlated with triglyceride,total cholesterol,and low density lipoprotein (P<0.05).Apo M and triglyceride,total cholesterol,low density lipoprotein cholesterol,high density lipoprotein,albumin was significantly posi-tively correlated,and ESR was negatively correlated with anti ds-DNA antibody (P<0.05).Conclusion The level of Apo M was significantly lower in SLE patients which showed a significant positive correlation with triglyceride,total cholesterol, low density lipoprotein,high density lipoprotein and albumin.And showed a negatively correlated with anti ds-DNA antibody and ESR.Disease activity index of Apo M is larger.
9.Some Advice on Experimental Teaching Reformation of Food Testing
Jinrui XU ; Weiyun YE ; Kun HU ; Xiaoyong WU
Chinese Journal of Medical Education Research 2003;0(03):-
Food Testing was the experimental and applied basic courses for Prevent Medicine.According as the problems in teaching,some advice on teaching content,teaching method,and laboratory construction and management was discussed in order to cultivate the innovative specialties and develop the students' experimental ability.
10.The application of concept center method on the teaching of physical and chemical analysis of food
Xiaoyong WU ; Weiyun YE ; Yongqing GAO ; Kun HU ; Jinrui XU
Chinese Journal of Medical Education Research 2003;0(02):-
Physical and Chemical Analysis of Food is one of the important courses of hygiene quarantine speciality,food science and engineering speciality,food quality and safety speciality,and so on. The application of concept center method on the teaching of the course was discussed in the article. The prolegomenon of the course and the eleventh chapter of the course--Determination of Gene Modified Food had been worked as two examples.