1.Humanism Care For Uremia Patients
Chinese Medical Ethics 1995;0(04):-
Humanism care meets the need of the development of the whole society, the need of transformation of modern medicine pattern it is also the great need for uremia patients who thirst for health.Uremia patients with psychological distress will be greatly improved through following aspects: enhancing quality of medical staff,making more communications with patients and providing health education to them.In a word,humanism care for uremia patients will make them feel more love and improve their living states.
2.Relation of hepatitis C virus level and genotypes to response to interferon treatment
Kun LI ; Lihui WANG ; Jun YE
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Objective To investigate the relationship between HCV genotype and its level and the response to interferon (IFN).Methods HCV genotypes were detected by type-specific primes modified PCR assay.HCV-RNA levels were determined by branched DNA(bDNA) singnal PCR amplification fluorescence assay.The patients with chronic hepatitis C virus infection treated with IFN ? were divided into different groups according to genotypes or levels of HCV.Result Patients with pre-treatment HCV levels10 9 eq?L -1 showed partial responses (28 6%) or no responsces (28 6%).Stasistical analysis showed significant difference (P
4.The effect of low molecular heparin and Galectin-3on the cell migration and proliferation of vascular endothelial cells
Yang DING ; Shengyun WAN ; Kun YE
Acta Universitatis Medicinalis Anhui 2017;52(5):651-655
Objective To explore the effect of the association of low molecular heparin and Galectin-3 on the cell migration and cell proliferation of vascular endothelial cell from mesenchymal stem cells.Methods Depending on the administration, this study was divided into four groups: low molecular weight heparin group, adding 20 mg/L low molecular weight heparin into the cells;Galectin-3 group, adding 5 mg/L Galectin-3 into the cells;combination group, adding 20 mg/L low molecular weight heparin and 5 μg/ml of Galectin-3 into the cells;control group, equal volume of PBS buffer into the cells.The proliferation of vascular endothelial cell was to be detected by EdU incorporation,the cell growth cycle of vascular endothelial cell was to be detected by flow cytometry,and the cell migration of vascular endothelial cell was to be detected by scrath test.Then to investigate the effect of different conditions on the migration and proliferation of vascular endothelial cell.Results The OD490 of MWH group, Galectin-3 group, combined group and control group were (0.285±0.018), (0.297±0.041), (0.351±0.016), and (0.233±0.005) respectively, which indicates that the combined group could increase the cell proliferation significantly(P<0.05).Cultured for 24 hours, the cell migration rate was(42.02±7.62), (45.82±3.96), (68.53±11.22),and (34.21±3.99), suggesting that combined group have the largest cell migration(P<0.05).Conclusion The association of low molecular heparin and Galectin-3 could improve the cell migration and cell proliferation of vascular endothelial cell from esenchymal stemcells significantly.
5.Application status and evaluation of transilluminated powered phlebectomy in varicose vein surgery
Kun YE ; Huagang ZHU ; Kangmin YU
International Journal of Surgery 2011;38(6):402-404
Varicose veins is the main clinical manifestations of the chronic venous insufficiency.TIPP transilluminated powered phlebectomy,a new minimally invasive surgery,received much attention while surgical techniques aimed at treating varicose vein were constantly updated.In this article,TIPP in the varicose vein surgery is reviewed from its history,operating techniques and advantages,and TIPP's future is being prospected.
6.Co-integration relation between residents’ health and economic development in China
Chunlei HAN ; Zhi YE ; Kun HAN ; Gaizhen JIA ; Dahua LIU
Chinese Journal of Health Policy 2015;8(12):67-71
Objective:This paper aims to explore the relationship between the residents’ health and economic de-velopment to provide a scientific basis which will promote the coordinated economy and health development. Methods:Adopting the entropy method, we could calculate the comprehensive health evaluation index. In combining the co-inte-gration and error correction models, we could analyze the long-term and short-term relationships between our country residents’ level of health since 2000 and the national macro-economic development information. The Granger causality test served as a good method used in testing the casual relationships. Results: The health and economic development has a co-integration relationship which is -0. 6216 in the short-term correction. The economic development extent is the Granger cause of residents’ health status. Conclusion:There is not only a long-term equilibrium, but also a short-term relationship between the residents’ health and economic development in our country. The economic growth pro-motes residents’ health status while the promotion of residents’ health to economic growth is not obvious.
7.Sensitive surface-enhanced Raman spectroscopy detection of thiram based on hybrid substrate
Kun GUO ; Xin CHEN ; Lin YE ; Suhong CHEN
Military Medical Sciences 2015;(1):44-47
Objective To prepare hybrid substrate and apply it to detect thiram with surface-enhanced Raman spectros-copy( SERS) which provides unique molecular vibration information .Methods The Au substrate was prepared by deposi-tion of gold film on the silver substrate that had a rough surface .The Au substrate was treated with amination as a linker with the silver sol before the hybrid substrate was formed .With PATP as a probe molecule ,the Raman intensity of PATP on the Au substrate and the hybrid substrate was compared ,respectively .Results and Conclusion PATP had stronger Raman intensity on hybrid substrate than on the Au , and the detection limit was 10 -9 mol/L.This method can be used for quanti-tative detection on the hybrid substrate by SERS .
8.Programming and rebuild of network system in hospital information construction
Ye LUO ; Yutu TIAN ; Kun JIANG ; Haibo TU
Chinese Medical Equipment Journal 2004;0(08):-
Objective To construct a safe,stable and credible system for the running of network system and improve its application effect.Method Starting with the information system construction in Xijing hospital,the existent network system was programmed and rebuilt by establishing a assistant switch core and constructing multi-center redundancy link.Conclusion The rebuilt information system of Xijing hospital attains the anticipated effect,and shows rationality and practicability in use.What's more,combined with actual experience,the rebuild of hospital network system was summarized and suggestions were given.
9.Clinical features and drug selection in 54 patients with inflammatory bowel disease and comorbid autoimmune disease
Xianlan ZHU ; Gaoshuang LIU ; Ye ZHU ; Kun WANG ; Lianzhen YU
Chinese Journal of Digestion 2016;36(10):681-685
Objective To explore the differences in disease location,pathological feature,disease severity,extraintestinal manifestations and drug treatment between inflammatory bowel disease (IBD) patients with comorbid autoimmune disease (AD) and simple IBD patients.Methods From January 2009 to December 2014,the clinical data of 54 IBD patients with comorbid AD and at the same period 74 simple hospitalized IBD patients were retrospectively analyzed.According to IBD type and whether combined with AD,patients were divided into Crohn's disease (CD)+AD group (n=16),CD group (n=26),ulcerative colitis (UC)+AD group (n=38) and UC group (n=48).Chi square test was performed to compare the differences in disease severity,location,extraintestinal manifestations and drug treatment between IBD patients with and without AD.Results There was no statistically significant difference in location among four groups (all P>0.05).The most common concomitant AD of IBD was rheumatoid arthritis (20.4%,11/54) and ankylosing spondylitis (13.0%,7/54).The proportion of mild active patients of CD+ AD group was lower than that of CD group (2/16 vs 53.8% (14/26),x2 =7.180,P=0.007),while the proportion of severe active patients was significantly higher that of CD group (6/16 vs 0,x2 =8.519,P=0.004).There was no statistically significant difference in moderate active patients between the two groups (P=0.808).Main type of patients of UC+ AD group (76.3 %,29/38) and UC group (68.8 %,33/48) were moderate active patients.There was no statistically significant difference in disease stage and location (all P>0.05).The incidence of extraintestinal manifestations of IBD+AD group (55.6 %,30/ 54) was significantly higher than that of IBD group (9.5 %,7/74,x2 =32.279,P<0.01),and the main manifestation was arthritis (37.0% (20/54) vs 5.4% (4/74),x2=20.504,P<0.01).The rate of glucocorticoid and immunosuppressant application in IBD+AD group was higher than that of IBD group (40.7% (22/54) vs 17.6%(13/74),x2 =8.438,P=0.004;20.4%(11/54) vs 0,x2=14.000,P< 0.01).Conclusions The condition of patients with IBD and comorbid AD is more severe,and the incidence of extraintestinal manifestations is higher.Early treated with glucocorticoid and immunosuppressant could effectively achieve remission.