No abstract available.
Child* ; Humans ; Mass Screening* ; Seoul*

This article describes the activity of the "Medical termonology practical committee (MTPC) of Korean Medical Association (KMA). In 2001, MTPC of KMA published the 4th edition of "English-Korean, Korean-English Medical terminology" which contains about 5,000 medical terms. The MTPC will continue reviewing the vocabularies. Obsolete terms will be discarded, new terms will be added, and the remainder will be revised by through-going revision of vocabulary. Our aim is to reflect the current usage of medical terms in the form of easily understandable Korean terms.
Vocabulary

Objective To investigate the sensitivity and specificity of different assays for detection of Chlamydia trachomatis . Methods Chlamydia trachomatis was determined in samples of cervical secretions from 213 patients with nongonococcal urethritis or genitourinary tract infection by direct immunofluorescence assay (DFA ) ,gold-immunochromatographic assay (ICA ) and real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) .Results Comparing the positive rates of Chlamydia trachoma-tis detected by adopting the DAF ,FQ-PCR and the ICA methods showed the statistical difference (P<0 .05) .The sensitivity and specificity of Chlamydia trachomatis detected by DFA ,ICA and FQ-PCR were 95 .1% ,60 .2% ,97 .3% and 93 .2% ,99 .2% , 99 .3% ,respectively .The sensitivity of the DFA and FQ-PCR methods was higher than that of the ICA method ,difference was sta-tistically significant(P<0 .05) ,The specificity of the ICA and FQ-PCR methods was higher than that of the DFA method ,differ-ence was statistically significant (P<0 .05) .Conclusion The FQ-PCR method has higher sensitivity and higher specificity for the detection of Chlamydia trachomatis and can provide the reliable basis for clinically diagnosing the infection of Chlamydia trachom-atis .The primary medical units is suitable to adopt the ICA method for detecting Chlamydia trachomatis .

Objective To study the etiology of surgical infection and antibiotic resistance of infective bacteria,so as to provide evidence for clinical treatment.Method The composition and antibiotic resistance in surgical specimens of pathogenic bacteria from January 2008 to December 2010 was analyzed retrospectively.Results A total of 321 pathogens isolated,Gram-negative bacteria 201,accounting for 62.6％,Gram-positive cocci 114,accounting for 35.5％,Fungus 6,accounting for 1.9％.Escherichia coli 116(36.1％),Klebsiella pneumoniae 24(7.5％),Staphylococcus aureus 34(10.6％),Pseudomonas aeruginosa 18(5.6％),Enterococcus faecalis 16(5.0％).Staphylococcus species of Staphylococci methicillinresistant Staphylococcus atureus(MRS),Coagulase-negative staphylococci MRS and ultra wide-spectrum beta-lactamases(ESBLs)detection rate was 52.9％(18/34),83.7％(36/43)and 35.0％(49/140),respectively.The resistance rates of Gram-negative bacilli to piperacillin/tazobactam,ceftazidime,amikacin,imipenem and meropenem were below 20％,Gram-positive cocci,staphylococci to new compound sulfamethoxazole,minocycline,rifampin,vancomycin,teicoplanin and fusidic acid resistance rates were less than 40％,various pathogens had varies resistance.Conclusions Specimens of surgical infection pathogens widely distribute in different drug-resistant bacteria,some strains of multi-drug resistant infection,causing clinical failure of empirical therapy,clinical laboratory susceptibility results should be based on the rational use of antibiotics,to avoid the overuse of antibiotics.

Objective To evaluate the clinical efficacy of lamivudine in the treatment of pulmonary tuberculosis patients with chronic hepatitis B.Methods 98 pulmonary tuberculosis patients with chronic hepatitis B were divided into two groups.49 patients in the control group were given conventional treatment,and 49 patients in the observation group received lamivudine on the basis of conventional treatment.The clinical efficacy and adverse reactions of two groups were compared.Results During treatment,the liver dysfunction rate of the observation group was 10.20％,which was significantly lower than 18.37％ of the control group(x2 =4.21,P ＜ 0.05).After treatment,the relevant indicators of liver function and HBV-DNA in the observation group were significantly lower than those in the control group(t =10.72,10.11,7.68,all P＜0.05).Conclusion Lamivudine in the treatment of pulmonary tuberculosis patients with chronic hepatitis B has significant effect,which is beneficial to the patients' early recovery,and it is worthy of extensive promotion and application.

With a high incidence, cancer pain is an unresolved clinical problem right now. Many randomized controlled studies have shown that intrathecal infusion of analgesic drugs is an effective way to relieve pain. Intrathecal drug infusion system provides cli-nicians with exact individualized treatment approach in the effective analgesia, but with minimum side effects. Patients who received in-trathecal analgesic therapy in the early stage would get more benefit. Before implanting intrathecal drug delivery devices, it is needed to test analgesic effect firstly, and the proper implementation of the test period is extremely important. This effectively maintaining time decides whether the patients need intrathecal analgesia system. However, there are many factors that may affect its application in clin-ic. This article focuses on the treatment principle, patient selection, testing, technical problems and complications when applying intra-thecal drug delivery devices.

?AlM: To observe the application effect of hyperbaric oxygen in the patients with optic atrophy and influence degree for the hemodynamic parameters.?METHODS: Fifty patients with optic atrophy in our hospital from January 2012 to January 2014 were objected, they were randomly divided into control group ( conventional optic atrophy treatment group ) and observation group ( conventional treatment and hyperbaric oxygen treatment group ) , each group was 25 cases. Statistical analysis of two group before and after treatment eyesight, vision acuity, visual field defect and ophthalmic artery, central retinal artery blood flow parameters were undergone.?RESULTS: The sight, visual field sensitivity and field vision defect of observation group were all better than those of control group at first, second and third course after the treatment, arteriae ophthalmica and arteriae centralis retinae EDV and PSV were all higher than those of control group, Pl and Rl were all lower than those of control group were all significant differences (P<0. 05).? CONCLUSlON: The application effect of hyperbaric oxygen in the patients with optic atrophy is better, and the influence of treatment method for the ocular hemodynamic parameters are more active.

microRNA(miRNA) ,a class of small noncoding RNAs,negatively regulates gene expression at post-transcriptional level, and is involved in many fundamental biological processes, including development,apoptosis and cell proliferation, p53 is a transcription factor that plays a critical role in the control of cell cycle and apoptosis. Aberrant expression of either miRNA or p53 intimately links to tumorigenesis. This article reviews recent advances in the study of inter-relatioship between miRNA and p53 in tumorigenesis.

Objective To reduce the hypokalemia caused by inner environment imbalance effectively in order to lower the death rate and improve the prognosis for patients with severe cranial injury.Methods Seventy-five patients with severe cranial injury who had hypokalemia were studied retrospoctively from October 10th,2003 to July 30th,2006.Results The waves of electrocardiogram and changes of illness condition was closely observed,the volume:of intake and output and kalium outcome was accurately recorded.Kalium was supplemented as early as possible.the amount was adjusted by the use of dehydratins agents and biochemical kalium.Only timely and effective monitoring and treatment could complications be reduced or prevented.Conclusions Severe cranial injury is one of the most severe trauma,timely monitoring and nursing measures are key point for rectification of hypokalemia for patients with severe cranial injury.

Objective:To explore the correlation between lipid metabolism and coronary atherosclerosis in advanced aged patients with coronary heart disease (CHD) .Methods:A total of 95 advanced aged patients ,who were suspec-ted CHD and received coronary angiography (CAG) in our hospital from Dec 2010 to Dec 2013 ,were selected .Ac-cording to CAG results ,the 95 patients were divided into CHD group (n=43) and non-CHD group (n=52) .Their clinical data were retrospectively analyzed ,and the correlations between blood lipids and coronary atherosclerosis were analyzed .Results:Compared with non-CHD group , the ratio of low density lipoprotein cholesterol to high density lipoprotein cholesterol (LDL-C/HDL-C) [ (2.01 ± 0.65) vs .(2.38 ± 0.92) , P=0.024] significantly rose in CHD group .In CHD group ,number of diseased coronary vessel was positively correlated with triglyceride (TG) level ,LDL-C/HDL-C ,TG/HDL-C and atherogenic index of plasma (AIP) , r=0.183~0.256 (P<0.05 all) ,and inversely correlated with HDL-C level (r= -0.243 ,P<0.05);coronary stenosis degree was positively correlated with LDL-C/HDL-C ,TG/HDL-C and AIP (r=0.225~0.331 ,P<0.05) ,and inversely correlated with HDL-C level (r= -0.261 ,P<0.05) .In CHD group ,total Gensini score was positively correlated with blood lipid indexes (r=0.068~0.201 ,P<0.05 or <0.01) and inversely correlated with HDL-C level (r= -0.138 ,P<0.01) .Con-clusion:Elevated plasma HDL-C level can delay progression of coronary heart disease in advanced aged patients with coronary heart disease .LDL-C/HDL-C and AIP are indexes evaluating severity and risk of coronary atherosclerosis in patients with coronary heart disease .