1.Osteometric Assessment of Coracoid Process of Scapula-Clinical Implications
Journal of Surgical Academia 2018;8(2):3-10
The coracoid process is a bony projection arising from the antero-lateral aspect of the scapula. The variation in the height and length of the coracoid process are responsible for altered size and shape of the space between the coracoacromial arch and the rotator cuff. The study was conducted on sixty-four dry adult human scapulae of unknown age and sex with a view to elucidate the morphological and osteometric details. The length of coracoid process on right side was 41.01±3.55 mm and it was found to be 40.88±3.83 mm on left sided. The breadth of coracoid process was observed as 13.93±1.13 mm and 13.25±1.26 mm on right and left side respectively and the difference between the two sides was statistically significant (p=0.026). Thickness of the coracoid process was 8.59±1.32 mm and 8.01±1.16 mm in right and left sided scapulae. The acromiocoracoid distance was found to be 38.48±4.03 mm on right side and 35.51±3.83 mm on left sided scapulae and the difference between to the two sides showed high statistically significance (p=0.004). Mean coracoglenoid distance was noted 26.23±3.05 mm and 24.94±2.75 mm on right and left sided scapulae respectively. Values of the thickness of coracoid process recorded in the present study are at appreciable variance with the result of previous study. The coracoid process constitutes an important component of the scapular glenoid construct and is involved in many surgical interventions on the glenohumeral joint. Comprehension of standard morphometric details of the coracoid process is vital in traumatic cases, surgical interventions and replacement surgeries in the shoulder region.
Coracoid
;
process
;
scapula
;
osteometric
;
clinical
2.Emphysematous pyelonephritis in a diabetic leading to renaldestruction: pathological aspects of a rare case
Archana Shetty ; Vijaya C ; Geethamani V ; Savitha Anil Kumar
The Malaysian Journal of Pathology 2013;35(1):103-106
Emphysematous pyelonephritis is a severe, potentially fatal necrotizing pyelonephritis with a
variable clinical presentation, ranging from mild abdominal pain to septic shock. The majority
of cases occur in diabetics with poor glycemic control, while a small percentage may be due to
urinary tract obstruction. We present a case of a 57 year old male patient, diabetic on treatment,
presenting with left fl ank pain and poor stream of urine since one week. Laboratory tests revealed
that the patient had electrolyte imbalance, ketoacidosis and high blood sugar. Urine culture was
positive for Escherichia coli with a signifi cant colony count. Radiological examination gave a
diagnosis of Left Type 1 Emphysematous Pyelonephritis. Inspite of giving vigorous resuscitation
and antibiotics with nephrostomy, the patient had to undergo nephrectomy due to extensive renal
parenchymal destruction.
The nephrectomy specimen was studied in detail to know the histopathological fi ndings in a case
of diabetic patient with emphysematous pyelonephritis. We present this case not only because of
it being a rare complication of diabetes, but also to focus on the histopathological fi ndings of the
same, documentation of which is limited in literature.
3.Giant Cell Tumour of the Distal Ulna: A Rare Presentation
Ruben Jaya Kumar ; Vijayachandran V ; Dinesh Ernest ; Thirumal Manickam
Malaysian Orthopaedic Journal 2011;5(2):44-46
Giant-cell tumour (GCT) of bone, a primary yet locally
aggressive benign tumour, commonly affects patients
between the ages of 20 and 40 years, with the peak incidence occurring in the third decade. Women are affected slightly more than men. The distal end of the ulna is an extremely uncommon site for primary bone tumours in general and giant cell tumours in particular. Wide resection of the distal ulna is the recommended treatment for GCT in such locations. Radio-ulna convergence and dorsal displacement of the ulna stump are known complications following ulna resection proximal to the insertion of the pronator quadratus.
This leads to reduction in grip power and forearm rotatory
motion. Stabilization of the ulna stump with extensor carpi
ulnaris (ECU) tendon after wide resection of the tumour has
been described in the literature. We report a case of GCT of distal end of ulna treated with wide resection and
stabilization with ECU tendon.
4.Quantification of 17-desacetyl norgestimate in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and its application to bioequivalence study
Saxena Ashish ; Gupta Kumar Arun ; Kumar Praveen V. ; Nainar Sundaramoorthi M. ; Bob Manoj ; Kasibhatta Ravisekhar
Journal of Pharmaceutical Analysis 2015;(2):93-100
A rapid and sensitive ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was developed and validated for the estimation of 17-desacetyl norgestimate in human plasma using solid-phase extraction technique. 17-desacetyl norgestimate D6 was used as the internal standard. Simple gradient chromatographic conditions and mass spectrometric detection enabled accurate and precise measurement of 17-desacetyl norgestimate at sub-picogram levels. The proposed method was validated for a linear range of 20–5000 pg/mL with a correlation coefficient Z 0.9988. The intra-run and inter-run precision and accuracy were within 10%. The overall recoveries for 17-desacetyl norgestimate and 17-desacetyl norgestimate D6 were 96.30%and 93.90%, respectively. The total run time was 4.5 min. The developed method was applied for the determination of the pharmacokinetic parameters of 17-desacetyl norgestimate following a single oral administration of a norgestimate and ethinyl estradiol 0.250 mg/0.035 mg tablets in 35 healthy female volunteers.
7.Adenoviral conjunctivo-corneal epithelitis: an unusual clinical presentation of epidemic keratoconjunctivitis study
Sudesh Kumar ARYA ; Badri Prasad BADHU ; Ritu AMATYA ; V G RAMACHANDRAN ; Poonam LAVAJU
International Eye Science 2009;9(8):1444-1447
Adenoviral keratoconjunctivitis is caused by adenovirus serotypes 8,19,37.Typical signs of adenoviral con-junctivitis include preauricular lymphadenopathy, conjunc-tival hyperemia, chemosis, subconjunctival hemorrhage and follicular conjunctival reaction. Corneal involvement in adenoviral keratoconjunctivitis is variable. Most patients have a diffuse, fine, superficial keratitis with focal, elevated, punctate epithelial lesions which become subepithelial opacities later. We had a 35 years old male who had unusual clinical presentation of adenoviral conjunctivitis in the form of conjunctivo-corneal epithelitis which has not been described in the literature.Patient was managed successfully by conserva-tive treatment alone. Conjunctivo-corneal epithelitis can be unusual clinical presentation of adenoviral kerato-conjunctivitis.
8.In vivo magnetic resonance imaging morphometry of the patella bone in South Indian population.
Reshma MUHAMED ; Vasudha V SARALAYA ; B V MURLIMANJU ; Ganesh Kumar CHETTIAR
Anatomy & Cell Biology 2017;50(2):99-103
Racial differences exist in the dimensions of structures and the commercially available prostheses are designed based on the Caucasians. In this context, the goal of the present investigation was to determine the gender wise measurements of patella bone in South Indians. The present study included axial magnetic resonance images of the knee joint from 140 South Indian adults (70 males, 70 females; aged between 20–70 years). The angle, width, thickness, lateral facet width, facet thickness, ratio of the lateral facet, the relative thickness and ratio of facet thickness were measured in the patella by using the digital ruler. The statistical analysis was performed by using the SPSS software. The dimensions exhibited statistically highly significant sexual dimorphism (P≤0.001). The mean value was higher in males than females except for the ratio of patellar lateral facet and patellar facet thickness ratio. It was observed that the males exhibit more variability than females in all the measurements of patella except patellar thickness, patellar facet thickness, patellar relative thickness, and patellar facet thickness ratio. The present study of the in vivo morphometry of patella bone from the South Indians can provide a population and gender specific database for the morphometric measurements of the patella. We believe that the data of the present study will be useful to the orthopaedician during the procedures like arthroplasty of the total knee, patellofemoral arthroplasty, resurfacing of patella, and designing the prosthetic implant.
Adult
;
Arthroplasty
;
Female
;
Humans
;
Knee
;
Knee Joint
;
Magnetic Resonance Imaging*
;
Male
;
Patella*
;
Patellofemoral Joint
;
Prostheses and Implants
;
Prosthesis Implantation
9.Ocular Manifestations of Venomous Snake Bite over a One-year Period in a Tertiary Care Hospital.
K V PRAVEEN KUMAR ; S PRAVEEN KUMAR ; Nirupama KASTURI ; Shashi AHUJA
Korean Journal of Ophthalmology 2015;29(4):256-262
PURPOSE: Ocular manifestations in snake-bite injuries are quite rare. However, the unusual presentations, diagnosis and their management can pose challenges when they present to the ophthalmologist. Early detection of these treatable conditions can prevent visual loss in these patients who are systemically unstable and are unaware of their ocular condition. To address this, a study was conducted with the aim of identifying the various ocular manifestations of snake bite in a tertiary care center. METHODS: This is a one-year institute-based prospective study report of 12 snake bite victims admitted to a tertiary hospital with ocular manifestations between June 2013 to June 2014, which provides data about the demographic characteristics, clinical profiles, ocular manifestations, and their outcomes. RESULTS: Twelve cases of snake bite with ocular manifestations were included of which six were viper bites, three were cobra bites and three were unknown bites. Six patients presented with bilateral acute angle closure glaucoma (50%), two patients had anterior uveitis (16.6%) of which one patient had concomitant optic neuritis. One patient had exudative retinal detachment (8.3%), one patient had thrombocytopenia with subconjunctival hemorrhage (8.3%) and two patients had external ophthalmoplegia (16.6%). CONCLUSIONS: Bilateral angle closure glaucoma was the most common ocular manifestation followed by anterior uveitis and external ophthalmoplegia. Snake bite can result in significant ocular morbidity in a majority of patients but spontaneous recovery with anti-snake venom, steroids and conservative management results in good visual prognosis.
Acute Disease
;
Adolescent
;
Adult
;
Animals
;
Antivenins/therapeutic use
;
*Elapidae
;
Female
;
Follow-Up Studies
;
Glaucoma, Angle-Closure/diagnosis/*etiology/therapy
;
Humans
;
Male
;
Middle Aged
;
Ophthalmoplegia/diagnosis/*etiology/therapy
;
Prospective Studies
;
Snake Bites/*complications/diagnosis/therapy
;
Snake Venoms/*poisoning
;
Tertiary Healthcare
;
Time Factors
;
Uveitis, Anterior/diagnosis/*etiology/therapy
;
*Viperidae
;
Young Adult
10.Acute kidney injury (AKI) with the use of antibiotic-impregnated bone cement in primary total knee arthroplasty.
Bernard P H LAU ; V Prem KUMAR
Annals of the Academy of Medicine, Singapore 2013;42(12):692-695
Acute Kidney Injury
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chemically induced
;
Aged
;
Anti-Bacterial Agents
;
administration & dosage
;
adverse effects
;
Arthroplasty, Replacement, Knee
;
Bone Cements
;
adverse effects
;
Drug-Related Side Effects and Adverse Reactions
;
complications
;
Female
;
Humans
;
Surgical Wound Infection
;
prevention & control
;
Treatment Outcome