E. coli endotoxin was injected into 15 white male rabbits iv. and fever ensued one month and three months later after both testicles of these rabbits were excised. Then the comparison of the fever peak was made between the electric acupuncture experimental group and the control group one month later, which showed a markable statistical significance. Three months later, the comparison of the temperature response index was made between these two groups, which also showed a great statistical significance. The estradiol in the blood plasma showed a considerable increase after one month compar. ing with the preoperation, while the testosterone in the blood plasma showed a great decrease after three months. Thus, it is shown that the effect of electric acupuncture inhibition of the temperature Increase was related to sex hormone levels in the blood plasma.

The fever was induced by intraperitoneal injecting of refined E.Coli endotoxin(ET). The cAMP level and the activity of adenylate cyclase (AC) in differen brain areas of rat were assayed.Both cAMP and AC in hypothalamus were increased significantly at the peak of fever in comparing with the control group (P

Fourty rats were divided into four groups and the aseptic inflammation was induced by subcutaneous injection of cronton oil into the back of 30 rats. Body temperature were gradually rose up after injection. The highest temperature appeared on the second day, then run down in the following days, and went back to normal on the eighth day. Brain were dissected in 10 normal rats without fever(group 1), other 10 rats at the peak of fever(group 2), and another 10 rats in the recovery phase on the third day (group 3). Ten rats in group 4 were used for observing the whole process of temperature change from injection day to the eighth day without brain dissection. The results showed that at the peak of fever, the levels of both cAMP and AC activities in hypo. thalamus were increased (P

Sixteen hybrid dogs were randomly divided inio two groups: (1) HSG grouphemorrhagic shock pretreated with ginseng fruit saponin at 30 min before bleeding and(2) HS group, hemorrhagic shock pretreated with same volum of saline. The hemorrhagicshock was induced by bleeding from carotid artery. Mean arterial blood pressure of 5. 3 kPawas maintained for 4 hr. In there 2 group of animals, the survival rates average pressurebefore put to death, end hemorrhage were obviously all different (P

Fever was induced by ET in rabbits. The PGE_2 level in the plasma and cerebrospinal fluid (CSF) was measured at peak of fever in both electric acupuncture and control group. The results showed that when the body temperature of animals rose to the peak, the PGE_2 levels in the plasma and CSF were higher than that before fever. (P