As a summary of the research progress of chemical modification of lead compounds by saccharides and their derivatives, this article studies the linkage style of saccharides with lead compounds and bioactivity changes of the modified lead compounds. The result shows that the modified lead compounds can decrease the toxicity and side effect efficiently, and enhance the pharmacal effect. Therefore, it is a promising research project to modify lead compounds by saccharides.

The Study prepared the microcapsule of Famotiding-chitosan, examined the relationships between several effect factors and the quality of the microcapsule, and as well as determined the best preparation technology of Famotidine-chitosan microcapsule.

Objective:To study the morphological characteristics of the mental canal and its relation to the mandibular canal and incisor nerve canal.Methods:The anterior parts of the mandibular canal, the mental canal and the origin of the incisor nerve canal were dissected and measured directly on 13 cases of Chinese wet mandible specimens fixed with formalin. The mandibular canal, the mental canal and the incisor nerve canal of another 21 sides of decalcified mandibles were dissected and measured. Results:The anterior terminal part of the mandibular canal divided into mental canal and incisor nerve canal. Most of the mental canal bended backward, upward and outward then opened to the mental foramen. Mental canal's length was (5.61?1.07) mm averagely and its diameter (2.53? 0.47) mm. The horizontal distance from the anterior border of mental foramen to the anterior end of mandibular canal was (2.82?1.29) mm. The vertical distance from the inferior border of mental foramen to the superior border of mandibular canal was (3.83?1.43) mm. The angle between mental canal and mandibular canal was (63.57?13.71)?. Mental canal contained mental nerve and mental blood vessels. Conclusions:The anterior end of mandibular canal extends and becomes mental canal then opens to the mental foramen.

Objective To develop a new method for correction of the deformity of the complete bilateral cleft lip with short pre-lip. Methods Two specimens with the complete bilateral cleft lip was chosen to investigate the arterial supply to the pre-lip. The arteries were observed by radiography when the specimen was infused with lead oxide. 16 patients with the complete bilateral cleft lip and shortage in the length of pre-lip were enrolled in this study. Taking advantage of the unique character of arterial supply of complete bilateral cleft lip, those with short pre-lip were corrected. Photos of them were taken when preand post-operation for further measurement. And more than 1 year following-up was conducted to judge if the results were good enough or not. 30 babies were chosen as a control group to confirm the results of surgury objectively. Results Post nasal septal arteries were found to supply the pre-lip of the bilateral complete cleft lip. Appearance of 16 patients was good after surgery or 1 years later. There was no statistical significant difference between the patients and control group in the measurement data but nasal-lip angle. Conclusion It is an effective way to correct deformity of the bilateral cleft lip with short pre-lip by taking advantage of post nasal septal arterie's flap.

OBJECTIVETo study relationship between facial nerve root and its surrounding vessels.

METHODS49 sides facial nerve root and its surrounding vessel were dissected and observed.

RESULTSFacial nerve root and its surrounding vessels forming compression was found to be 24.5% (12/49), creating contact was found to be 14.3% (7/49). The main vessels compressed or (and) contacted facial nerve root were anterioinferior cerebellar artery (68.4%), posterioinferior cerebellar artery (4.1%), malformed vertebral artery (4.1%) and anterioinferior cerebellar vein.

CONCLUSIONSFacial nerve root compressed by offending vesselsare was mainly cause of hemifacial spasm.

Adult ; Blood Vessels ; anatomy & histology ; innervation ; physiopathology ; Facial Nerve ; anatomy & histology ; blood supply ; physiopathology ; Hemifacial Spasm ; physiopathology ; Humans